ZNFX1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ZNFX1 , zinc finger NFX1-type containing 1, IMD91 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 2138982 HomoloGene: 10877 GeneCards: ZNFX1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Zinc finger NFX1-type containing 1 is a protein that in humans is encoded by the ZNFX1 gene. [5]
ZNFX1 deficiency in humans is associated with severe multisystem inflammatory disease. [6] Affected individuals may develop liver, lung or kidney failure, seizures and hemophagocytic lymphohistiocytosis (HLH) upon viral infections. Intermittent monocytosis is a hallmark laboratory finding in ZNFX1 deficiency. The disorder is thought to result from alterations in the half-life of the mRNA of interferon-stimulated genes (ISG) and is also associated with poorer clearance of viral infections in monocytes.
Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. It is associated with acrodermatitis enteropathica.
RoXaN also known as ZC3H7B, is a protein that in humans is encoded by the ZC3H7B gene. RoXaN is a protein that contains tetratricopeptide repeat and leucine-aspartate repeat as well as zinc finger domains. This protein also interacts with the rotavirus non-structural protein NSP3.
Zinc finger protein 35 is a protein that in humans is encoded by the ZNF35 gene.
Zinc finger and BTB domain containing 11 is a protein that in humans is encoded by the ZBTB11 gene.
Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.
Zinc finger, DHHC-type containing 14 is a protein that in humans is encoded by the ZDHHC14 gene.
Zinc finger protein 208 is a protein that in humans is encoded by the ZNF208 gene.
Zinc finger protein 426 is a protein that in humans is encoded by the ZNF426 gene.
Zinc finger CCCH-type containing 10 is a protein that in humans is encoded by the ZC3H10 gene.
Zinc finger DHHC-type containing 21 is a protein that in humans is encoded by the ZDHHC21 gene.
Zinc finger C2HC-type containing 1B is a protein that in humans is encoded by the ZC2HC1B gene.
Zinc finger C3H1-type containing is a protein that in humans is encoded by the ZFC3H1 gene.
Vascular endothelial zinc finger 1 is a protein that in humans is encoded by the VEZF1 gene.
Zinc finger SWIM-type containing 3 is a protein that in humans is encoded by the ZSWIM3 gene.
Zinc finger MYM-type containing 1 is a protein that in humans is encoded by the ZMYM1 gene.
Zinc finger BED-type containing 5 is a protein that in humans is encoded by the ZBED5 gene.
Zinc finger protein 142 is a protein that in humans is encoded by the ZNF142 gene.
Zinc finger protein 717 is a protein that in humans is encoded by the ZNF717 gene.
Tripartite motif containing 38 is a protein that in humans is encoded by the TRIM38 gene.
Zinc finger RANBP2-type containing 1 is a protein that in humans is encoded by the ZRANB1 gene.