Zinc finger protein 574

ZNF574
Identifiers
Aliases	ZNF574 , FP972, zinc finger protein 574
External IDs	MGI: 2442951; HomoloGene: 11238; GeneCards: ZNF574; OMA:ZNF574 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	42,081,552 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	24,782,917 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; right testis; ; left testis; ; oocyte; ; vena cava; ; parotid gland; ; tendon of biceps brachii; ; lateral nuclear group of thalamus; ; nipple; ; body of tongue;
	Top expressed in
	seminiferous tubule; ; Rostral migratory stream; ; primary oocyte; ; spermatocyte; ; motor neuron; ; spermatid; ; ciliary body; ; secondary oocyte; ; internal carotid artery; ; vas deferens;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding ; metal ion binding ; nucleic acid binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	nucleus ;
Biological process	transcription, DNA-templated ; regulation of transcription, DNA-templated ; regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	64763
	232976
	ENSG00000105732
	ENSMUSG00000045252
	Q6ZN55
	Q8BY46
	NM_022752 ; NM_001330519
	NM_001168506 ; NM_175477
	NP_001317448 ; NP_073589
	NP_001161978 ; NP_780686
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 21, 2024

Zinc finger protein 574 is a protein that in humans is encoded by the ZNF574 gene. ^[5] The protein is predicted to enable DNA-binding transcription activator activity, and to be involved with RNA polymerase II-specific and RNA polymerase II cis-regulator region sequence specific DNA binding.^[6]

Related Research Articles

DNA-directed RNA polymerase II subunit RPB9 is an enzyme that in humans is encoded by the POLR2I gene.

Zinc finger protein 281 is a protein that in humans is encoded by the ZNF281 gene.

Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene.

snRNA-activating protein complex subunit 3 is a protein that in humans is encoded by the SNAPC3 gene.

Replication initiator 1 is a protein that in humans is encoded by the REPIN1 gene. The protein helps enable RNA binding activity as a replication initiation-region protein. The make up of REPIN 1 include three zinc finger hand clusters that organize polydactyl zinc finger proteins containing 15 zinc finger DNA- binding motifs. It has also been predicted to help in regulation of transcription via RNA polymerase II with it being located in the nucleoplasm. Expression of this protein has been seen in the colon, spleen, kidney, and 23 other tissues within the human body throughout.

Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.

Zinc finger protein 219 is a protein that in humans is encoded by the ZNF219 gene.

Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is encoded by the BRF2 gene.

RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene.

Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.

Zinc finger protein 330 is a protein that in humans is encoded by the ZNF330 gene.

Probable methyltransferase TARBP1 is an enzyme that in humans is encoded by the TARBP1 gene.

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.

Zinc finger protein 473 is a protein that in humans is encoded by the ZNF473 gene.

TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa is a protein that in humans is encoded by the TAF1D gene.

Zinc finger protein 208 is a protein that in humans is encoded by the ZNF208 gene.

Zinc finger protein 334 is a protein that in humans is encoded by the ZNF334 gene.

Vascular endothelial zinc finger 1 is a protein that in humans is encoded by the VEZF1 gene.

TATA-box binding protein associated factor 7 like is a protein that in humans is encoded by the TAF7L gene.

ZNF865 is a C2H2 member of the zinc finger family of proteins. Structurally, ZNF865 consists of 20 different zinc finger domains, 6 disordered regions, 2 transactivation domains, and 2 TGEKP domains. Diseases associated with ZNF865 expression include Parkinson’s disease, esophageal cancer, and musculoskeletal diseases. Lack of expression of ZNF865 has been associated with increased incidence of Parkinson’s disease, worse outcome measures in esophageal cancer, and increased incidence of musculoskeletal diseases.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000105732 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045252 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Zinc finger protein 574" . Retrieved 2017-04-14.
↑ https://www.ncbi.nlm.nih.gov/gene/64763

Zinc finger protein 574

Related Research Articles

References

Further reading