Citatuzumab bogatox

Last updated
Citatuzumab bogatox
Monoclonal antibody
Type Fab fragment
Source Humanized (from mouse)
Target TACSTD1
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
Formula C3455H5371N921O1060S18
Molar mass 77348.44 g·mol−1
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Citatuzumab bogatox (VB6-845) is a monoclonal antibody Fab fragment fused with bouganin, a ribosome inactivating protein from the plant Bougainvillea spectabilis. [1] It has undergone preclinical development for the treatment of ovarian cancer and other solid tumors. [2]

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References

  1. International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
  2. Viventia Biotech Inc.: VB6-845 Archived 2010-03-29 at the Wayback Machine