| Race details | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dates | 17 April 1965 | ||||||||||||
| Stages | 1 | ||||||||||||
| Distance | 272 km (169.0 mi) | ||||||||||||
| Winning time | 5h 47' 29" | ||||||||||||
| Results | |||||||||||||
| 
 | |||||||||||||
The 49th Tour of Flanders cycling classic was held on Saturday, 17 April 1965. The race was won by Dutch rider Jo de Roo in a two-man sprint with Edward Sels. [1] 51 of 119 riders finished. [2]
The race started in Ghent and finished in Gentbrugge – covering 240 km. There were six categorized climbs: [1]
| Rank | Rider | Team | Time | 
|---|---|---|---|
| 1 |  Jo de Roo  (NED) | Televizier | 5h 47' 29" | 
| 2 |  Edward Sels  (BEL) | Solo–Superia | s.t. | 
| 3 |  Georges Van Coningsloo  (BEL) | Peugeot-BP–Michelin | + 33" | 
| 4 |  Willy Vannitsen  (BEL) | Ford France–Gitane | s.t. | 
| 5 |  Jean Stablinski  (FRA) | Ford France–Gitane | s.t. | 
| 6 |  Rik Van Looy  (BEL) | Solo–Superia | s.t. | 
| 7 |  Carmine Preziosi  (ITA) | Pelforth–Sauvage–Lejeune | + 58" | 
| 8 |  Gustaaf De Smet  (BEL) | Wiels–Groene Leeuw | s.t. | 
| 9 |  Arthur Decabooter  (BEL) | Wiels–Groene Leeuw | s.t. | 
| 10 |  Vic Van Schil  (BEL) | Mercier–BP–Hutchinson | s.t. |