Virginia Ruano Pascual and Paola Suárez were the two-time defending champions, but they were defeated in the second round by Anna Chakvetadze and Elena Vesnina.
Cara Black and Rennae Stubbs were the defending champions, but did not play together. Stubbs partnered with Lisa Raymond but lost in the first round to Stéphanie Cohen-Aloro and Selima Sfar.
Virginia Ruano Pascual and Paola Suárez were the defending champions, but Suárez did not participate due to injury. Ruano Pascual partnered Conchita Martínez, but lost in the first round to Jennifer Hopkins and Mashona Washington.
Samantha Stosur and Scott Draper defeated Liezel Huber and Kevin Ullyett in the final 6–2, 2–6, [10–6] to win the mixed doubles title at the 2005 Australian Open. This was the first Grand Slam title for both Stosur and Draper, and would be Draper's only Grand Slam title.
Lindsay Davenport and Lisa Raymond were the defending champions but only Raymond competed that year with Martina Navratilova.
Kim Clijsters defeated Lindsay Davenport in the final, 6–4, 7–5 to win the women's singles tennis title at the 2003 Indian Wells Masters.
Lisa Raymond and Rennae Stubbs were the defending champions but they competed with different partners that year, Raymond with Lindsay Davenport and Stubbs with Elena Bovina.
Serena and Venus Williams defeated Virginia Ruano Pascual and Paola Suárez in the final, 6–2, 7–5 to win the ladies' doubles tennis title at the 2002 Wimbledon Championships. It was their second Wimbledon doubles title together and sixth major title together overall.
Serena and Venus Williams defeated Chanda Rubin and Sandrine Testud in the final, 4–6, 6–1, 6–4 to win the women's doubles tennis title at the 1999 US Open. It was the second doubles major title for the Williams sisters, and their second step towards completing the career Golden Slam in doubles.
Lindsay Davenport and Lisa Raymond were the defending champions but they competed with different partners in 2004, Davenport with Corina Morariu and Raymond with Martina Navratilova.
Virginia Ruano Pascual and Paola Suárez were the defending champions and won in the final 6–2, 6–3, against Svetlana Kuznetsova and Martina Navratilova in straight sets. This was Ruano Pascual's 4th career Grand Slam doubles title and her 2nd title at the US Open. It was also Suárez' 4th career Grand Slam doubles title and her 2nd title at the US Open.
The doubles Tournament at the 2006 NASDAQ-100 Open took place between March 20 and April 6 on the outdoor hard courts of the Tennis Center at Crandon Park in Key Biscayne, United States. Lisa Raymond and Samantha Stosur won the title, defeating Liezel Huber and Martina Navratilova in the final.
Lisa Raymond and Rennae Stubbs were the defending champions, but lost in third round to Kim Clijsters and Meghann Shaughnessy.
Elena Bovina and Rennae Stubbs were the defending champions, but had different outcomes. While Bovina did not compete this year, Stubbs partnered with Cara Black and successfully defended her title, defeating Elena Likhovtseva and Magdalena Maleeva 6–0, 6–1 in the final. It was the 2nd title in the year for the pair, and the 14th title for Black and 44th title for Stubbs, in their respective careers.
Virginia Ruano Pascual and Paola Suárez were the defending champions and successfully defended their title, defeating Lisa Raymond and Rennae Stubbs 6–4, 6–2 in the final.
Liezel Huber and Magdalena Maleeva were the defending champions, but competed this year with different partners. Huber teamed up with Ai Sugiyama and were eliminated in the quarterfinals, while Maleeva teamed up with Katarina Srebotnik and lost in the first round.
Lisa Raymond and Rennae Stubbs were the defending champions, but Raymond did not compete in this edition. Stubbs teamed up with Elena Bovina and lost in quarterfinals to Virginia Ruano Pascual and Paola Suárez.
Lisa Raymond and Rennae Stubbs were the defending champions and both players played in the final, but with different partners.
Lindsay Davenport and Lisa Raymond were the defending champions, but Raymond did not compete this year. Davenport teamed up with Corina Morariu and were eliminated in first round.
Lindsay Davenport and Lisa Raymond were the defending champions, but Davenport did not compete this year in order to focus on the singles tournament.
Liezel Huber 
Magdalena Maleeva 
Shinobu Asagoe 
