Alisa Kleybanova won in the final 6–3, 6–2, against Elena Dementieva.
Kim Clijsters was the defending champion, but decided not to compete this year.
Jelena Janković was the defending champion, but lost to compatriot Ana Ivanovic in the fourth round.
Lucie Hradecká was the defending champion, but withdrew from the event.
Number one seed Lucie Hradecká defeated unseeded Ajla Tomljanović 6–1, 7–6(7–4) in the final to win the women's singles title at the inaugural Sparta Prague Open.
Magdaléna Rybáriková is the defending champion, but she lost in the first round to the American qualifier Jamie Hampton.
Jelena Dokić was the defending champion, but lost in the second round to compatriot Olivia Rogowska.
Caroline Wozniacki was the defending champion, but she chose not to participate.
Agnieszka Radwańska won the title, defeating Simona Halep 7–5, 6–0 in the final.
Maria Sharapova was the defending champion, but withdrew because of a stomach virus. Li Na defeated Angelique Kerber for the title, 1–6, 6–3, 6–1.
Sara Errani and Roberta Vinci were the defending champions, but chose not to participate in doubles.
Anastasia Pavlyuchenkova and Lucie Šafářová won the title, defeating Cara Black and Marina Erakovic in the final, 6–2, 6–4.
Sara Errani and Roberta Vinci were the defending champions, but lost to Serena and Venus Williams in the quarterfinals.
Andrea Hlaváčková and Lucie Hradecká won the title, defeating Ashleigh Barty and Casey Dellacqua in the final, 6–7(4–7), 6–1, 6–4.
This article displays the qualifying draw for the Women's Singles at the 2008 US Open.
Irina-Camelia Begu was the defending champion, but lost in the second round to Jana Čepelová.
Agnieszka Radwańska was the defending champion, but withdrew before her quarterfinal match with a right thigh injury.
Venus Williams was the defending champion, but chose to compete in St. Petersburg instead.
Chuang Chia-jung and Darija Jurak were the defending champions, but chose not to participate together. Chuang played alongside Zheng Saisai, but lost in the first round to Gabriela Dabrowski and Jeļena Ostapenko. Jurak teamed up with Anastasia Rodionova, but lost in the second round to Dabrowski and Ostapenko.
Iga Świątek defeated Anett Kontaveit in the final, 6–2, 6–0 to win the singles title at the 2022 Qatar Open.
Jelena Dokić (qualified)
Rebecca Marino (first round)
Magdaléna Rybáriková (first round)
Evgeniya Rodina (first round)
Zhang Shuai (qualified)
Lucie Hradecká (qualified)
Tamira Paszek (first round)
Mirjana Lučić (first round)
Jill Craybas (first round)
Alberta Brianti (first round)
Kirsten Flipkens (qualifying competition)
Junri Namigata (qualifying competition)
Sania Mirza (qualified)
Anne Keothavong (first round)
Arantxa Rus (qualified)
Pauline Parmentier (first round)
Kateryna Bondarenko (first round)
