| Singles | |
|---|---|
| 2018 Tashkent Open | |
| Champion |  Margarita Gasparyan |
| Runner-up | Anastasia Potapova |
| Final score | 6–2, 6–1 |
| Draw | 32 |
| Seeds | 8 |
Kateryna Bondarenko was the defending champion, but chose not to participate.
Margarita Gasparyan won the title, defeating qualifier and compatriot Anastasia Potapova in the final 6–2, 6–1. Ranked at World No. 299, Gasparyan became the third-lowest ranked player ever to win a WTA singles title.
Irina-Camelia Begu (first round)
Vera Lapko (quarterfinals)
Tamara Zidanšek (first round)
Stefanie Vögele (first round)
Tatjana Maria (second round)
Anna Karolína Schmiedlová (quarterfinals) Evgeniya Rodina (second round) Dalila Jakupović (quarterfinals)| Semifinals | Final | ||||||||||||
 Kateryna Kozlova | 2 | 3 | |||||||||||
| Q | Anastasia Potapova | 6 | 6 | ||||||||||
| Q | Anastasia Potapova | 2 | 1 | ||||||||||
| PR | Margarita Gasparyan | 6 | 6 | ||||||||||
| PR | Margarita Gasparyan | 4 | 6 | 7 | |||||||||
| Mona Barthel | 6 | 1 | 5 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | I-C Begu | 3 | 2 | ||||||||||||||||||||||||
| K Kozlova | 6 | 6 | K Kozlova | 7 | 6 | ||||||||||||||||||||||
 F Ferro | 1 | 77 | 6 | F Ferro | 5 | 4 | |||||||||||||||||||||
 J Fett | 6 | 64 | 1 | K Kozlova | 6 | 6 | |||||||||||||||||||||
 N Hibino | 6 | 6 | 6 | AK Schmiedlová | 3 | 2 | |||||||||||||||||||||
 E Bouchard | 3 | 3 | N Hibino | 65 | 4 | ||||||||||||||||||||||
| Q |  D Radanović | 3 | 0 | 6 | AK Schmiedlová | 77 | 6 | ||||||||||||||||||||
| 6 | AK Schmiedlová | 6 | 6 | K Kozlova | 2 | 3 | |||||||||||||||||||||
| 4 | S Vögele | 6 | 63 | 3 | Q | A Potapova | 6 | 6 | |||||||||||||||||||
| Q | A Potapova | 4 | 77 | 6 | Q | A Potapova | 6 | 6 | |||||||||||||||||||
| O Danilović | 6 | 6 | O Danilović | 3 | 3 | ||||||||||||||||||||||
| WC | A Kalinskaya | 4 | 1 | Q | A Potapova | 7 | 2 | 6 | |||||||||||||||||||
| M Kostyuk | 4 | 3 | 8 | D Jakupović | 5 | 6 | 1 | ||||||||||||||||||||
 A Rus | 6 | 6 | A Rus | 1 | 66 | ||||||||||||||||||||||
| A Blinkova | 4 | 7 | 4 | 8 | D Jakupović | 6 | 78 | ||||||||||||||||||||
| 8 | D Jakupović | 6 | 5 | 6 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | T Maria | 6 | 6 | ||||||||||||||||||||||||
| N Vikhlyantseva | 1 | 2 | 5 | T Maria | 2 | 6 | 62 | ||||||||||||||||||||
 S Sharipova | 2 | 2 | PR | M Gasparyan | 6 | 3 | 77 | ||||||||||||||||||||
| PR | M Gasparyan | 6 | 6 | PR | M Gasparyan | 3 | 6 | 6 | |||||||||||||||||||
| Q |  F Stollár | 3 | 6 | 6 | Q | F Stollár | 6 | 2 | 1 | ||||||||||||||||||
| K Nara | 6 | 3 | 4 | Q | F Stollár | 77 | 6 | ||||||||||||||||||||
| WC | V Zvonareva | 6 | 6 | WC | V Zvonareva | 62 | 4 | ||||||||||||||||||||
| 3 | T Zidanšek | 1 | 4 | PR | M Gasparyan | 4 | 6 | 7 | |||||||||||||||||||
| 7 | E Rodina | 7 | 6 | M Barthel | 6 | 1 | 5 | ||||||||||||||||||||
 M Fręch | 5 | 2 | 7 | E Rodina | 5 | 6 | 4 | ||||||||||||||||||||
| M Barthel | 4 | 6 | 6 | M Barthel | 7 | 4 | 6 | ||||||||||||||||||||
| WC | N Abduraimova | 6 | 3 | 3 | M Barthel | 6 | 7 | ||||||||||||||||||||
| E Alexandrova | 3 | 2 | 2 | V Lapko | 3 | 5 | |||||||||||||||||||||
| Q | I Jorović | 6 | 6 | Q | I Jorović | 2 | 4 | ||||||||||||||||||||
| PR | B Jovanovski Petrović | 1 | 3 | 2 | V Lapko | 6 | 6 | ||||||||||||||||||||
| 2 | V Lapko | 6 | 6 | ||||||||||||||||||||||||
Anastasia Potapova (qualified) Conny Perrin (first round) Fanny Stollár (qualified)
Viktoriya Tomova (first round) Misaki Doi (qualifying competition)
Harriet Dart (first round)
Elena Rybakina (first round) Bibiane Schoofs (qualifying competition)| First round | Qualifying competition | ||||||||||||
| 1 | Anastasia Potapova | 6 | 6 | ||||||||||
| WC | Yasmina Karimjanova | 3 | 1 | ||||||||||
| 1 | Anastasia Potapova | 65 | 6 | 6 | |||||||||
| 5 | Misaki Doi | 77 | 3 | 2 | |||||||||
| Amandine Hesse | 3 | 2 | |||||||||||
| 5 | Misaki Doi | 6 | 6 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 2 | Conny Perrin | 6 | 64 | 4 | |||||||||
| Ivana Jorović | 1 | 77 | 6 | ||||||||||
| Ivana Jorović | 77 | 6 | |||||||||||
| 8 | Bibiane Schoofs | 61 | 3 | ||||||||||
| WC | Akgul Amanmuradova | 5 | 3 | ||||||||||
| 8 | Bibiane Schoofs | 7 | 6 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 3 | Fanny Stollár | 6 | 3 | 6 | |||||||||
 Barbora Štefková | 4 | 6 | 1 | ||||||||||
| 3 | Fanny Stollár | 77 | 6 | ||||||||||
| Varvara Flink | 64 | 3 | |||||||||||
| Varvara Flink | 6 | 3 | 6 | ||||||||||
| 7 | Elena Rybakina | 4 | 6 | 3 | |||||||||
| First round | Qualifying competition | ||||||||||||
| 4 | Viktoriya Tomova | 2 | 4 | ||||||||||
| Dejana Radanović | 6 | 6 | |||||||||||
| Dejana Radanović | 7 | 7 | |||||||||||
| Alexandra Panova | 5 | 5 | |||||||||||
| Alexandra Panova | 4 | 6 | 6 | ||||||||||
| 6 | Harriet Dart | 6 | 1 | 1 | |||||||||
Marie Bouzková was the defending champion, but she chose not to participate. Dalma Gálfi won the title, defeating Sofia Kenin in the final, 7–5, 6–4.
İpek Soylu and Jil Teichmann were the defending champions, but they chose not to participate.
Viktória Kužmová and Aleksandra Pospelova won the title, defeating Anna Kalinskaya and Anastasia Potapova in the final, 7–5, 6–2.
Dalma Gálfi and Fanny Stollár were the defending champions, but chose not to participate this year.
Sloane Stephens was the defending champion, but did not participate this year as she was recovering from foot surgery.
Kiki Bertens was the two-time defending champion, but lost in the quarterfinals to Kirsten Flipkens.
Anett Kontaveit was the defending champion, but lost in the first round to Veronika Kudermetova.
Anastasia Pavlyuchenkova was the defending champion, but chose to compete in Linz instead.
Georgina García Pérez and Fanny Stollár were the defending champions, but chose not to participate together. García Pérez played alongside Renata Voráčová, but lost in the quarterfinals to Anna Blinkova and Anastasia Potapova.
Bianca Andreescu won her first WTA Tour title, defeating Angelique Kerber in the final, 6–4, 3–6, 6–4. Andreescu became the first wildcard to win the title in the tournament's history and the youngest Indian Wells champion since Serena Williams in 1999. This also marked the second year in a row where a player won the tournament without having won a WTA singles title prior.
Petra Kvitová was the defending champion, but lost to Kiki Bertens in the quarterfinals in a replay of the previous year’s final.
This was the first edition of the tournament.
Svetlana Kuznetsova was the defending champion, however she was unable to defend her title due to visa issues.
Hsieh Su-wei was the defending champion, but lost to Nao Hibino in the quarterfinals.
Kiki Bertens was the defending champion and successfully defended her title, defeating Elena Rybakina in the final, 6–1, 6–3. This would be Bertens' final WTA Tour singles title before her retirement in July 2021.
Bianca Andreescu was the defending champion from when the event was last held in 2019, but lost in the third round to Ons Jabeur.
Aryna Sabalenka was the defending champion, but she chose not to compete this year.
Madison Keys defeated Alison Riske in the final, 6–1, 6–2 to win the women's singles tennis title at the 2022 Adelaide International 2.
Anastasia Potapova defeated Veronika Kudermetova in the final, 6–3, 6–1 to win the singles title at the 2022 İstanbul Cup. It was her maiden WTA Tour title.
Yulia Putintseva was the defending champion, but was defeated in the semifinals by Krunić.
Marie Bouzková defeated Anastasia Potapova in the final, 6–0, 6–3 to win the singles tennis title at the 2022 Prague Open. It was her maiden WTA Tour title.