The 2020 Nevada Wolf Pack football team represented the University of Nevada, Reno in the 2020 NCAA Division I FBS football season. The Wolf Pack were led by fourth–year head coach Jay Norvell and played their home games at Mackay Stadium. They were members of the Mountain West Conference.
The 2020 Notre Dame Fighting Irish football team represented the University of Notre Dame in the 2020 NCAA Division I FBS football season. The team was led by Brian Kelly in his 11th season at Notre Dame. The Fighting Irish played their home games at Notre Dame Stadium in Notre Dame, Indiana.
The 2020 Cincinnati Bearcats football team represented the University of Cincinnati in the 2020 NCAA Division I FBS football season. The Bearcats played their home games at Nippert Stadium and competed as members of the American Athletic Conference. They were led by fourth-year head coach Luke Fickell.
The 2020 North Carolina Tar Heels football team represented the University of North Carolina at Chapel Hill as a member of the Atlantic Coast Conference (ACC) during the 2020 NCAA Division I FBS football season. The Tar Heels were led by head coach Mack Brown, in the second season of his second stint at North Carolina and his 12th overall season. The team played their home games at Kenan Memorial Stadium.
The 2020 Virginia Tech Hokies football team represented Virginia Tech during the 2020 NCAA Division I FBS football season. The Hokies were led by fifth-year head coach Justin Fuente and played their home games at Lane Stadium in Blacksburg, Virginia, competing as members of the Atlantic Coast Conference (ACC).
The 2020 Memphis Tigers football team represented the University of Memphis in the 2020 NCAA Division I FBS football season. The Tigers played their home games at Liberty Bowl Memorial Stadium in Memphis, Tennessee, and competed in the American Athletic Conference. They were led by first-year head coach Ryan Silverfield.
The 2020 East Carolina Pirates football team represented East Carolina University in the 2020 NCAA Division I FBS football season. The Pirates, led by second-year head coach Mike Houston, played their home games at Dowdy–Ficklen Stadium as members of the American Athletic Conference.
The 2020 Houston Cougars football team represented the University of Houston in the 2020 NCAA Division I FBS football season. The Cougars played their home games at TDECU Stadium in Houston, Texas, and competed in the American Athletic Conference. They were led by second-year head coach Dana Holgorsen.
The 2020 South Florida Bulls football team represented the University of South Florida (USF) during the 2020 NCAA Division I FBS football season. The Bulls were led by first-year head coach Jeff Scott and played their home games at Raymond James Stadium in Tampa, Florida. They competed as members of the American Athletic Conference.
The 2020 Liberty Flames football team represented Liberty University in the 2020 NCAA Division I FBS football season. They were led by second-year head coach Hugh Freeze and played their home games at Williams Stadium. The Flames competed as an FBS independent.
The 2020 Appalachian State Mountaineers football team represented Appalachian State University during the 2020 NCAA Division I FBS football season. The Mountaineers were led by first-year head coach Shawn Clark. Appalachian State played their home games at Kidd Brewer Stadium on the school's Boone, North Carolina, campus, and competed as a member of the East Division of the Sun Belt Conference.
The 2020 Georgia Southern Eagles football team represented Georgia Southern University during the 2020 NCAA Division I FBS football season. The Eagles played their home games at Paulson Stadium in Statesboro, Georgia, and competed in the East Division of the Sun Belt Conference. They were led by third-year head coach Chad Lunsford.
The 2020 FIU Panthers football team represented Florida International University (FIU) in the 2020 NCAA Division I FBS football season. The Panthers played their home games at Riccardo Silva Stadium in Miami, Florida, and competed in the East Division of Conference USA (C-USA). They were led by fourth-year head coach Butch Davis. The season was notably truncated due to several cancellations stemming from the effects of the worldwide COVID-19 pandemic.
The 2020 Florida Atlantic Owls football team represented Florida Atlantic University in the 2020 NCAA Division I FBS football season. The Owls played their home games at FAU Stadium in Boca Raton, Florida, and competed in the East Division of Conference USA (CUSA). They were led by head coach Willie Taggart, in his first year.
The 2020 UAB Blazers football team represented the University of Alabama at Birmingham in the 2020 NCAA Division I FBS football season. The Blazers played their final home games at Legion Field in Birmingham, Alabama, and competed in the West Division of Conference USA (C-USA). They were led by fifth-year head coach Bill Clark.
The 2020 Middle Tennessee Blue Raiders football team represented Middle Tennessee State University as a member of the East Division of Conference USA (C-USA) during the 2020 NCAA Division I FBS football season. Led by 15th-year head coach Rick Stockstill, the Blue Raiders compiled an overall record of 3–6 with a mark of 2–4 in conference play, placing fifth in the C-USA's East Division. The team played home games at Johnny "Red" Floyd Stadium in Murfreesboro, Tennessee.
The 2020 Western Kentucky Hilltoppers football team (WKU) represented Western Kentucky University in the 2020 NCAA Division I FBS football season. The Hilltoppers played their home games at the Houchens Industries–L. T. Smith Stadium in Bowling Green, Kentucky, as members of the East Division of Conference USA (C–USA). They were led by second-year head coach Tyson Helton.
The 2021 Old Dominion Monarchs football team represented Old Dominion University during the 2021 NCAA Division I FBS football season. The Monarchs played their home games at S.B. Ballard Stadium in Norfolk, Virginia, and competed in the East Division of Conference USA (C-USA). The team was coached by second-year head coach Ricky Rahne.
The 2021 East Carolina Pirates football team represented East Carolina University in the 2021 NCAA Division I FBS football season. The Pirates, led by third-year head coach Mike Houston, play their home games at Dowdy–Ficklen Stadium as members of the American Athletic Conference.
The 2021 SMU Mustangs football team represented Southern Methodist University during the 2021 NCAA Division I FBS football season. The Mustangs played their home games at Gerald J. Ford Stadium in University Park, Texas, a separate city within the city limits of Dallas, competed as members of the American Athletic Conference (AAC). The Mustangs were led by fourth-year coach Sonny Dykes—on November 29, it was announced that Dykes would leave the program to become the head coach at TCU. He finished at SMU with an overall record of 30–18.