ABCA9

ABCA9
Identifiers
Aliases	ABCA9 , EST640918, ATP binding cassette subfamily A member 9
External IDs	OMIM: 612507 MGI: 2386796 HomoloGene: 33332 GeneCards: ABCA9
Gene location (Human)
Chr.	Chromosome 17 (human)
End	69,060,949 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	110,059,022 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; tibial nerve; ; sural nerve; ; subcutaneous adipose tissue; ; pericardium; ; right lung; ; left uterine tube; ; right coronary artery; ; canal of the cervix; ; gastrocnemius muscle;
	Top expressed in
	sciatic nerve; ; ciliary body; ; otolith organ; ; iris; ; utricle; ; dermis; ; belly cord; ; conjunctival fornix; ; interventricular septum; ; body of femur;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding ; ATPase activity ; ATP binding ; ATPase-coupled transmembrane transporter activity ; lipid transporter activity ;
Cellular component	integral component of membrane ; membrane ; intracellular membrane-bounded organelle ;
Biological process	lipid transport ; transmembrane transport ;
	Sources:Amigo / QuickGO
Orthologs
	10350
	217262
	ENSG00000154258
	ENSMUSG00000041797
	Q8IUA7
	Q8K449
	NM_080283 ; NM_172386
	NM_147220
	NP_525022
	NP_671753
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 25, 2024

ATP-binding cassette sub-family A member 9 is a protein that in humans is encoded by the ABCA9 gene.^[5]

Function

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies ( ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import.^[5]

Related Research Articles

ATP-binding cassette sub-family A member 12 also known as ATP-binding cassette transporter 12 is a protein that in humans is encoded by the ABCA12 gene.

ATP-binding cassette transporter ABCA1, also known as the cholesterol efflux regulatory protein (CERP) is a protein which in humans is encoded by the ABCA1 gene. This transporter is a major regulator of cellular cholesterol and phospholipid homeostasis.

ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.

ATP-binding cassette sub-family G member 5 is a protein that in humans is encoded by the ABCG5 gene.

ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene.

ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene.

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.

ATP-binding cassette sub-family A member 7 is a protein that in humans is encoded by the ABCA7 gene.

ATP-binding cassette sub-family A member 3 is a protein that in humans is encoded by the ABCA3 gene.

ATP-binding cassette sub-family B member 7, mitochondrial is a protein that in humans is encoded by the ABCB7 gene.

ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.

ATP-binding cassette super-family B member 6, mitochondrial is a protein that in humans is encoded by the ABCB6 gene.

ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene.

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.

ATP-binding cassette sub-family D member 4 is a protein that in humans is encoded by the ABCD4 gene.

ATP-binding cassette sub-family G member 4 is a protein that in humans is encoded by the ABCG4 gene.

ATP-binding cassette sub-family A member 8 is a protein that in humans is encoded by the ABCA8 gene.

ATP-binding cassette sub-family B member 8, mitochondrial is a protein that in humans is encoded by the ABCB8 gene.

Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene.

ATP-binding cassette, sub-family A (ABC1), member 5 is a protein that in humans is encoded by the ABCA5 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000154258 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041797 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9".

External links

ABCA9 human gene location in the UCSC Genome Browser .
ABCA9 human gene details in the UCSC Genome Browser .

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000154258 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041797 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 "Entrez Gene: ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9".

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ABCA9

Contents

Function

Related Research Articles

References

Further reading

External links