ABCA9

Last updated

ABCA9
Identifiers
Aliases ABCA9 , EST640918, ATP binding cassette subfamily A member 9
External IDs OMIM: 612507; MGI: 2386796; HomoloGene: 33332; GeneCards: ABCA9; OMA:ABCA9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080283
NM_172386

NM_147220

RefSeq (protein)

NP_525022

NP_671753

Location (UCSC) Chr 17: 68.97 – 69.06 Mb Chr 11: 109.99 – 110.06 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

ATP-binding cassette sub-family A member 9 is a protein that in humans is encoded by the ABCA9 gene. [5]

Contents

Function

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. This gene is a member of the ABCA subfamily and is clustered with four other ABCA subfamily members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [5]

Related Research Articles

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ATP-binding cassette sub-family A member 12 also known as ATP-binding cassette transporter 12 is a protein that in humans is encoded by the ABCA12 gene.

<span class="mw-page-title-main">ABCA1</span> Mammalian protein found in Homo sapiens

ATP-binding cassette transporter ABCA1, also known as the cholesterol efflux regulatory protein (CERP) is a protein which in humans is encoded by the ABCA1 gene. This transporter is a major regulator of cellular cholesterol and phospholipid homeostasis.

<span class="mw-page-title-main">ABCG1</span> Mammalian protein found in Homo sapiens

ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.

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ATP-binding cassette sub-family G member 5 is a protein that in humans is encoded by the ABCG5 gene.

<span class="mw-page-title-main">ABCG8</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene.

<span class="mw-page-title-main">ABCA2</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene.

<span class="mw-page-title-main">ABCB9</span> Protein-coding gene in humans

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.

<span class="mw-page-title-main">ABCA3</span> Protein-coding gene in humans

ATP-binding cassette sub-family A member 3 is a protein that in humans is encoded by the ABCA3 gene.

<span class="mw-page-title-main">ABCB7</span> Protein-coding gene in humans

ATP-binding cassette sub-family B member 7, mitochondrial is a protein that in humans is encoded by the ABCB7 gene.

<span class="mw-page-title-main">ABCF2</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.

<span class="mw-page-title-main">ABCB6</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette super-family B member 6, mitochondrial is a protein that in humans is encoded by the ABCB6 gene.

<span class="mw-page-title-main">ABCF1</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene.

<span class="mw-page-title-main">ABCC10</span> Protein-coding gene in the species Homo sapiens

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.

<span class="mw-page-title-main">ABCD4</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family D member 4 is a protein that in humans is encoded by the ABCD4 gene.

<span class="mw-page-title-main">ABCG4</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family G member 4 is a protein that in humans is encoded by the ABCG4 gene.

<span class="mw-page-title-main">ABCA8</span> Protein-coding gene in the species Homo sapiens

ABC-type organic anion transporter ABCA8 is a protein that in humans is encoded by the ABCA8 gene.

<span class="mw-page-title-main">ABCB8</span> Protein-coding gene in the species Homo sapiens

ATP-binding cassette sub-family B member 8, mitochondrial is a protein that in humans is encoded by the ABCB8 gene.

<span class="mw-page-title-main">ABCC12</span> Protein-coding gene in the species Homo sapiens

Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene.

<span class="mw-page-title-main">CYP20A1</span> Protein-coding gene in the species Homo sapiens

CYP20A1 is a protein which in humans is encoded by the CYP20A1 gene.

<span class="mw-page-title-main">ABCA5</span> Protein-coding gene in the species Homo sapiens

Cholesterol transporter ABCA5 is a protein that in humans is encoded by the ABCA5 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000154258 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041797 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9".

Further reading