Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software. Combinatorial chemistry can be used for the synthesis of small molecules and for peptides.
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio.
In organic chemistry, the Ugi reaction is a multi-component reaction involving a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to form a bis-amide. The reaction is named after Ivar Karl Ugi, who first reported this reaction in 1959.
Sir David William Cross MacMillan is a Scottish chemist and the James S. McDonnell Distinguished University Professor of Chemistry at Princeton University, where he was also the chair of the Department of Chemistry from 2010 to 2015. He shared the 2021 Nobel Prize in Chemistry with Benjamin List "for the development of asymmetric organocatalysis". MacMillan used his share of the $1.14 million prize to establish the May and Billy MacMillan Foundation.
Morten Peter Meldal is a Danish chemist and Nobel laureate. He is a professor of chemistry at the University of Copenhagen in Copenhagen, Denmark. He is best known for developing the CuAAC-click reaction, concurrently with but independent of Valery V. Fokin and K. Barry Sharpless.
Peter John Stang is a German American chemist and Distinguished Professor of chemistry at the University of Utah. He was the editor-in-chief of the Journal of the American Chemical Society from 2002 to 2020.
Laura Lee Kiessling is an American chemist and the Novartis Professor of Chemistry at the Massachusetts Institute of Technology. Kiessling's research focuses on elucidating and exploiting interactions on the cell surface, especially those mediated by proteins binding to carbohydrates. Multivalent protein-carbohydrate interactions play roles in cell-cell recognition and signal transduction. Understanding and manipulating these interactions provides tools to study biological processes and design therapeutic treatments. Kiessling's interdisciplinary research combines organic synthesis, polymer chemistry, structural biology, and molecular and cell biology.
Younan Xia is a Chinese-American chemist, materials scientist, and bioengineer. He is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering, with joint appointments in the School of Chemistry & Biochemistry, the School of Chemical & Biomolecular Engineering, and Parker H. Petit Institute for Bioengineering & Bioscience at the Georgia Institute of Technology.
Anthony Gerard Martin Barrett FRS, FMedSci is a British chemist, and Sir Derek Barton Professor of Synthesis, Glaxo Professor of Organic Chemistry at Imperial College London. He is Director of the Wolfson Centre for Organic Chemistry in Medical Science. He was elected a fellow of the Royal Society in 1999 and Academy of Medical Sciences in 2003. He obtained a BSc as well as PhD from Imperial College London in 1973 and 1975 respectively.
Timothy P. Lodge is an American polymer scientist.
Abhik Ghosh is an Indian inorganic chemist and materials scientist and a professor of chemistry at UiT – The Arctic University of Norway in Tromsø, Norway.
Biman Bagchi is an Indian scientist currently serving as a SERB-DST National Science Chair Professor and Honorary Professor at the Solid State and Structural Chemistry Unit of the Indian Institute of Science. He is a theoretical physical chemist and biophysicist known for his research in the area of statistical mechanics; particularly in the study of phase transition and nucleation, solvation dynamics, mode-coupling theory of electrolyte transport, dynamics of biological macromolecules, protein folding, enzyme kinetics, supercooled liquids and protein hydration layer. He is an elected fellow of the Indian National Science Academy, the Indian Academy of Sciences, The World Academy of Sciences and an International honorary member of the American Academy of Arts and Sciences. Along with several scientific articles, he has authored three books, (i) Molecular Relaxation in Liquids, (ii) Water in Biological and Chemical Processes: From Structure and Dynamics to Function, and (iii) Statistical Mechanics for Chemistry and Materials Science.
Peter Wipf is the distinguished university professor of chemistry at the University of Pittsburgh. His research interests focus on the total synthesis of natural products, the discovery of new transformations of strained molecules, and the development of new pharmaceuticals. He is a Fellow of the Royal Society of Chemistry (RSC), the American Association for the Advancement of Science (AAAS), and the American Chemical Society (ACS).
Susan M. Kauzlarich is an American chemist and is presently a distinguished professor of chemistry at the University of California, Davis. At UC Davis, Kauzlarich leads a research group focused on the synthesis and characterization of Zintl phases and nanoclusters with applications in the fields of thermoelectric materials, magnetic resonance imaging, energy storage, opto-electronics, and drug delivery. Kauzlarich has published over 250 peer-reviewed publications and has been awarded several patents. In 2009, Kauzlarich received the annual Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring, which is administered by the National Science Foundation to acknowledge faculty members who raise the membership of minorities, women and disabled students in the science and engineering fields. In January 2022 she became Deputy Editor for the scientific journal, Science Advances.
Synthetic biopolymers are human-made copies of biopolymers obtained by abiotic chemical routes. Synthetic biopolymer of different chemical nature have been obtained, including polysaccharides, glycoproteins, peptides and proteins, polyhydroxoalkanoates, polyisoprenes.
Anthony W. Czarnik is an American chemist and inventor. He is best known for pioneering studies in the field of fluorescent chemosensors and co-founding Illumina, Inc., a biotechnology company in San Diego. Czarnik was also the founding editor of ACS Combinatorial Science. He currently serves as an adjunct visiting professor at the University of Nevada, Reno.
John A. Gladysz, an organometallic chemist, is a Distinguished Professor and holds the Dow Chair in Chemical Invention at Texas A&M University. Professor Gladysz is a native of the Kalamazoo, Michigan area. He obtained his B.S. degree from the University of Michigan (1971) and his Ph.D. degree from Stanford University (1974). He subsequently held faculty positions at UCLA (1974-1982) and the University of Utah (1982-1998). He then accepted the Chair of Organic Chemistry at the University of Erlangen-Nuremberg in Germany. In 2008, he returned to North America as a distinguished professor and holder of the Dow Chair in Chemical Invention at Texas A&M University.
M. G. Finn is an American chemist and professor at the Georgia Institute of Technology.
Yu-Shan Lin is a computational chemist. She is an associate professor of chemistry at Tufts University in the United States. Her research lab uses computational chemistry to understand and design biomolecules, with topics focusing on cyclic peptides, protein folding, and collagen.
Anne Bowen McCoy is a theoretical chemist. She is the Natt-Lingafelter Professor of Chemistry at the University of Washington, and her research interests include vibrational spectroscopy, hydrogen bonding, and charge-transfer bands. She received the 2023 Jack Simons Award in Theoretical Chemistry “for her development and application of theoretical methods for analyzing the vibrational spectra & dynamics of floppy molecules and clusters.”
