Chemical Abstracts Service

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Chemical Abstracts Service
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Headquarters Columbus, Ohio
  • United States
Official language
Manuel Guzman

Chemical Abstracts Service (CAS) is a division of the American Chemical Society. It is a source of chemical information. CAS is located in Columbus, Ohio, United States.



The two principal databases that support the different products are CAplus and Registry.

CAS References

CAS References consists of bibliographic information and abstracts for all articles in chemical journals worldwide, and chemistry-related articles from all scientific journals, patents, and other scientific publications.


Registry contains information on more than 130 million organic and inorganic substances, [2] and more than 64 million protein and nucleic acid sequences. [3] [4] The sequence information comes from CAS and GenBank, produced by the National Institutes of Health. The chemical information is produced by CAS, and is prepared by the CAS Registry System, which identifies each compound with a specific CAS registry number, index name, and graphic representation of its chemical structure.

The assignment of chemical names is done according to the chemical nomenclature rules for CA index names, which is slightly different from the internationally standard IUPAC names, according to the rules of IUPAC.


CAS databases are available via two principal database systems, STN, and SciFinder.


Chemical Abstracts Service Building B in August 2009. Columbus, Ohio CAS pelotonia.jpg
Chemical Abstracts Service Building B in August 2009. Columbus, Ohio

STN (Scientific & Technical Information Network) International is operated jointly [5] by CAS and FIZ Karlsruhe, and is intended primarily for information professionals, using a command language interface. In addition to CAS databases, STN also provides access to many other databases, similar to Dialog.


SciFinder is a database of chemical and bibliographic information. Originally a client application, a web version was released in 2008. [6] It has a graphics interface, and can be searched for chemical structures and reactions as well as literature in chemistry and related disciplines.

The client version is for chemists in commercial organizations. Versions for both the Windows and MacOS operating systems exist. SciFinder Scholar [7] is for universities and other academic institutions.[ needs update ]


CASSI stands for Chemical Abstracts Service Source Index. Since 2009, this formerly print and CD-ROM compilation is available as a free online resource to look up and confirm publication information. The online CASSI Search Tool provides titles and abbreviations, CODEN, ISSN, publisher, and date of first issue (history) for a selected journal. Also included is its language of text and language of summaries. [8]

The range is from 1907 to the present, including both serial and non-serial scientific and technical publications. The database is updated quarterly. [8] Beyond CASSI lists abbreviated journal titles from early chemical literature and other historical reference sources. [9]


CAS Headquarters Complex, constructed in 1965. Columbus, Ohio Chemical Abstracts Service complex.jpg
CAS Headquarters Complex, constructed in 1965. Columbus, Ohio

Chemical Abstracts (CA) began as a volunteer effort and developed from there. The use of volunteer abstractors was phased out in 1994. Chemical Abstracts has been associated with the American Chemical Society in one way or another since 1907. [10]

For many years, beginning in 1909, the offices of Chemical Abstracts were housed in various places on the Columbus, Ohio campus of The Ohio State University, including McPherson Laboratory and Watts Hall. [11] In 1965, CAS moved to a new 50-acre (200,000 m2) site on the west bank of the Olentangy River, just north of The Ohio State campus. This campus became well known in the Columbus area and famous as the site of many Columbus Symphony Orchestra pop concerts. In 2009, the campus consisted of three buildings.

In 1907, William A. Noyes had enlarged the Review of American Chemical Research, an abstracting publication begun by Arthur Noyes in 1895 that was the forerunner of Chemical Abstracts. When it became evident that a separate publication containing these abstracts was needed, Noyes became the first editor of the new publication, Chemical Abstracts.

E. J. Crane became the first Director of Chemical Abstracts Service when it became an American Chemical Society division in 1956. Crane had been CA editor since 1915, and his dedication was a key factor in its long-term success.

Dale B. Baker became the CAS Director upon Crane's retirement in 1958. According to CAS, his visionary view of CAS' potential "led to expansion, modernization, and the forging of international alliances with other information organizations." [12] CAS was an early leader in the use of computer technology to organize and disseminate information. [13]

The CAS Chemical Registry System was introduced in 1965. CAS developed a unique registry number to identify chemical substances. Agencies such as the U.S. Environmental Protection Agency and local fire departments around the world now rely on these numbers for the definite identification of substances. According to the ACS, this is the largest chemical substance database in the world.

In 2007, the ACS designated its Chemical Abstracts Service subdivision an ACS National Historic Chemical Landmark in recognition of its significance as a comprehensive repository of research in chemistry and related sciences. [14]

In 2021, CAS rebranded along with a change in logo. The organization updated their mission to be more focused on dynamic responsiveness due to ongoing changes within scientific industries and communities. [15]

See also

Related Research Articles

A CAS Registry Number, also referred to as CASRN or CAS Number, is a unique numerical identifier assigned by the Chemical Abstracts Service (CAS) to every chemical substance described in the open scientific literature, including organic and inorganic compounds, minerals, isotopes, alloys, mixtures, and nonstructurable materials. CASRNs are generally serial numbers, so they do not contain any information about the structures themselves the way SMILES and InChI strings do.

American Chemical Society American scientific society

The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio.

<i>The Journal of Organic Chemistry</i> Academic journal

The Journal of Organic Chemistry, colloquially known as JOC, is a peer-reviewed scientific journal for original contributions of fundamental research in all branches of theory and practice in organic and bioorganic chemistry. It is published by the publishing arm of the American Chemical Society, with 24 issues per year. According to the Journal Citation Reports, the journal had a 2017 impact factor of 4.805 and it is the journal that received the most cites in the field of organic chemistry. According to Web of Knowledge, eleven papers from the journal have received more than 1,000 citations, with the most cited paper having received 7,967 citations. The current Editor-in-Chief is Scott J. Miller from Yale University.

<i>Advances in Physics</i> Academic journal

Advances in Physics is a bimonthly scientific journal published by Taylor & Francis that was established in 1952. The journal is also issued as a supplement to the Philosophical Magazine. Peer review is determined on a case-by-case basis. The editors-in-chief are John Chalker and David Sherrington of Oxford University.

<i>Nature Materials</i> Academic journal

Nature Materials, is a peer-reviewed scientific journal published by Nature Publishing Group. It was launched in September 2002. Vincent Dusastre is the launching and current chief editor.

CODEN – according to ASTM standard E250 – is a six character, alphanumeric bibliographic code, that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas.

<i>Advanced Functional Materials</i> Academic journal

Advanced Functional Materials is a peer-reviewed scientific journal, published by Wiley-VCH. Established in February 2001, the journal began to publish monthly in 2002 and moved to 18/year in 2006, biweekly in 2008, and weekly in 2013.

Natural Product Reports is a monthly peer-reviewed scientific journal published by the Royal Society of Chemistry. It publishes reviews commissioned by the editorial board on all areas of natural products research. The Executive Editor is Richard Kelly.

FIZ Karlsruhe — Leibniz Institute for Information Infrastructure, formerly Fachinformationszentrum Karlsruhe, is a not-for-profit company with the public mission to make sci-tech information from all over the world publicly available and to provide related services in order to support the national and international transfer of knowledge and the promotion of innovation. The service institution is member of Gottfried Wilhelm Leibniz Scientific Community, a union of German research institutes. The institute provides information services and infrastructure for the academic and research community and maintains a collection of scientific databases.

Ei Compendex is an engineering bibliographic database published by Elsevier. The name "Compendex" stands for COMPuterized ENgineering inDEX. It covers scientific literature pertaining to engineering materials. It started in 1884 under the name Engineering Index (Ei) and its first electronic bulletin was issued in 1967. Elsevier purchased the parent company Engineering Information in 1998.

<i>Acta Biochimica et Biophysica Sinica</i> Academic journal

Acta Biochimica et Biophysica Sinica (ABBS) is a peer-reviewed, scientific journal, which publishes original research articles, short communications, and reviews in the fields of biochemistry and biophysics. Established in 1958, the journal is sponsored by the Institute of Biochemistry and Cell Biology, an institute of the Chinese Academy of Sciences, and is published monthly by Oxford Journals and was published by Blackwell Publishing prior to January 2009.

Zeitschrift für anorganische und allgemeine Chemie is a peer-reviewed scientific journal dealing with inorganic chemistry, published by Wiley-VCH. It is edited by Thomas F. Fässler, Thomas M. Klapötke, and Christian Limberg. It is published 24 times per year by Wiley-VCH. Originally the journal was published in German, but nowadays it is completely in English.

<i>ACS Nano</i> Academic journal

ACS Nano is a monthly, peer-reviewed, scientific journal, first published in August 2007 by the American Chemical Society. The current editor in chief is Paul S. Weiss. The journal publishes original research articles, reviews, perspectives, interviews with distinguished researchers, and views on the future of nanoscience and nanotechnology.

<i>Current Organic Chemistry</i> Academic journal

Current Organic Chemistry is a scientific review journal summarizing progress in the fields of asymmetric synthesis, organo-metallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry and analytical methods in organic chemistry. The journal is currently being edited by Dr. György Keglevich.

<i>Advanced Engineering Materials</i> Journal of material science

Advanced Engineering Materials is a peer-reviewed materials science journal that publishes monthly. Advanced Engineering Materials publishes peer-reviewed reviews, communications, and full papers, on topics centered around structural materials, such as metals, alloys, ceramics, composites, plastics etc..

<i>Transgenic Research</i> Academic journal

Transgenic Research, international in scope, is a bimonthly, peer-reviewed, scientific journal, published by Springer. The co-editors-in-chief are Paul Christou and Simon Lillico.

Chemical Engineering and Biotechnology Abstracts (CEABA-VTB) is an abstracting and indexing service that is published by DECHEMA, BASF, and Bayer Technology Services, all based in Germany. This is a bibliographic database that covers multiple disciplines.

Chemisches Zentralblatt is the first and oldest abstracts journal published in the field of chemistry. It covers the chemical literature from 1830 to 1969 and describes therefore the "birth" of chemistry as science, in contrast to alchemy. The information contained in this German journal is comparable with the content of the leading source of chemical information Chemical Abstracts Service (CAS), which started publishing abstracts in English in 1907.

<i>ACS Photonics</i> Academic journal

ACS Photonics is a monthly, peer-reviewed, scientific journal, first published in January 2014 by the American Chemical Society. The current editor in chief is Harry A. Atwater. The interdisciplinary journal publishes original research articles, letters, reviews and perspectives.

Antonio Zamora

Antonio Zamora is a consultant in the fields of computer programming, chemical information science, and computational linguistics who worked about chemical search systems and automatic spelling correction algorithms.


  1. "CAS Printed Products". CAS. Archived from the original on 2010-06-12. Retrieved 2009-12-02.
  2. "CAS Content at a Glance". Retrieved 18 March 2018.
  3. 50 Millionth Unique Chemical Substance Recorded in CAS REGISTRY Archived 2009-09-17 at the Wayback Machine ,
  4. "CAS Database Counter".
  5. FIZ Karlsruhe. "STN International: Home". Archived from the original on 2008-11-02. Retrieved 2008-07-10.
  6. "New SciFinder Available Via the Web Archived 2008-05-13 at the Wayback Machine ". CAS. April 6, 2008.
  7. SciFinder Scholar Archived 2006-10-06 at the Wayback Machine , CAS
  8. 1 2 "About the CAS Source Index (CASSI) Search Tool". Provided by Chemical Abstracts Service. American Chemical Society. December 2009. Retrieved 2016-08-26.
  9. Peters, Marion, Beyond CASSI (PDF), Chemical Abstracts Service, retrieved 2015-08-27
  10. American Chemistry Society. Chemical Landmarks, Chemical Abstracts. "ACS Online" . Retrieved 2009-08-01.
  11. Chemical Abstracts Service. About CAS, CAS 100th Anniversary, CAS History: Milestones [Online]. Archived 2010-06-12 at the Wayback Machine . Accessed 8.1.2009
  12. Chemical Abstracts Service. About CAS, CAS 100th Anniversary, CAS History: Milestones, 1958 Dale Baker [Online]. Archived 2010-06-12 at the Wayback Machine . Accessed 8.1.2009
  13. David Flaxbart. Issues in Science and Technology Librarianship, Winter 2007. Accessed 8.01.2009
  14. Chemical Abstracts Service (CAS) Archived 2012-07-12 at , American Chemical Society.
  15. "CAS launches new brand reflecting strategic evolution to empower smarter science". 2021-04-28.