ADAMTS15

ADAMTS15
Identifiers
Aliases	ADAMTS15 , ADAM metallopeptidase with thrombospondin type 1 motif 15
External IDs	OMIM: 607509; MGI: 2449569; HomoloGene: 8610; GeneCards: ADAMTS15; OMA:ADAMTS15 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	130,476,645 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	30,833,748 bp
RNA expression pattern
	Top expressed in
	decidua; ; myocardium of left ventricle; ; cardiac muscle tissue of right atrium; ; parietal pleura; ; right ventricle; ; apex of heart; ; lactiferous duct; ; right auricle of heart; ; left uterine tube; ; tibial arteries;
	Top expressed in
	aortic valve; ; ascending aorta; ; lumbar spinal ganglion; ; internal carotid artery; ; external carotid artery; ; tunica media of zone of aorta; ; left colon; ; trigeminal ganglion; ; gastric mucosa; ; mucous cell of stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding ; peptidase activity ; metalloendopeptidase activity ; heparin binding ; endopeptidase activity ; hydrolase activity ; metallopeptidase activity ; extracellular matrix binding ; metal ion binding ;
Cellular component	extracellular region ; cell surface ; extracellular space ; collagen-containing extracellular matrix ;
Biological process	proteolysis ;
	Sources:Amigo / QuickGO
Orthologs
	170689
	235130
	ENSG00000166106
	ENSMUSG00000033453
	Q8TE58
	P59384
	NM_139055
	NM_001024139 ; NM_001329420
	NP_620686
	NP_001019310 ; NP_001316349
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 18, 2025

A disintegrin and metalloproteinase with thrombospondin motifs 15 is a protein in humans encoded by the ADAMTS15 gene, a member of the ADAMTS family of multidomain extracellular protease enzymes.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000166106 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033453 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000166106 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033453 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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