APOL2

Last updated
APOL2
Identifiers
Aliases APOL2 , APOL-II, APOL3, apolipoprotein L2
External IDs OMIM: 607252; MGI: 2444921; HomoloGene: 12785; GeneCards: APOL2; OMA:APOL2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030882
NM_145637

NM_001081970
NM_001357895
NM_001357896

RefSeq (protein)

NP_112092
NP_663612

n/a

Location (UCSC) Chr 22: 36.23 – 36.24 Mb Chr 15: 77.63 – 77.64 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Apolipoprotein L2 is a protein that in humans is encoded by the APOL2 gene. [5] [6] [7]

Contents

This gene is a member of the apolipoprotein L gene family and protein in this family are lipid-binding proteins. This gene encodes a 37.1 kDa protein and The protein sequence contains 337bp. Localization of this protein is mainly found in the cytosol, nucleoplasm and additionally, it is also seen in the Nuclear bodies. [8] The involvement of this gene may affect in the movement of lipids and binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [7]

Amino acid sequence

MNPESSIFIE DYLKYFQDQV SRENLLQLLT DDEAWNGFVA AAELPRDEAD ELRKALNKLA SHMVMKDKNR HDKDQQHRQW FLKEFPRLKR ELEDHIRKLR ALAEEVEQVH RGTTIANVVS NSVGTTSGIL TLLGLGLAPF TEGISFVLLD TGMGLGAAAA VAGITCSVVE LVNKLRARAQ ARNLDQSGTN VAKVMKEFVG GNTPNVLTLV DNWYQVTQGI GRNIRAIRRA RANPQLGAYA PPPHVIGRIS AEGGEQVERV VEGPAQAMSR GTMIVGAATG GILLLLDVVS LAYESKHLLE GAKSESAEEL KKRAQELEGK LNFLTKIHEM LQPGQDQ [9] [10]

Total amino acids: 337 [9]

Interactions

APOL2 has been shown to interact with:

Splice variants

ApoL2 has 5 splice variants, [15]

This transcript has 6 exons, 12 domains and features are annotated, 263 variations are related this and maps to 35 oligo probes.

This transcript has 5 exons, 12 domains and features are annotated, 263 variations are related with this gene and maps to 37 oligo probes.

This transcript has 6 exons, is annotated with 3 domains and features, 62 variations are related with this gene and maps to 20 oligo probes.

This transcript has 6 exons, 12 domains and features are annotated, 331 variations are related with this gene and maps to 32 oligo probes.

This transcript has 5 exons, 4 domains and features are annotated, 104 variations are related with this gene and maps to 13 oligo probes.

Functions of the ApoL2

Related Research Articles

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References

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Further reading