Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials.
Nanochemistry is an emerging sub-discipline of the chemical and material sciences that deals with the development of new methods for creating nanoscale materials. The term "nanochemistry" was first used by Ozin in 1992 as 'the uses of chemical synthesis to reproducibly afford nanomaterials from the atom "up", contrary to the nanoengineering and nanophysics approach that operates from the bulk "down"'. Nanochemistry focuses on solid-state chemistry that emphasizes synthesis of building blocks that are dependent on size, surface, shape, and defect properties, rather than the actual production of matter. Atomic and molecular properties mainly deal with the degrees of freedom of atoms in the periodic table. However, nanochemistry introduced other degrees of freedom that controls material's behaviors by transformation into solutions. Nanoscale objects exhibit novel material properties, largely as a consequence of their finite small size. Several chemical modifications on nanometer-scaled structures approve size dependent effects.
The impact of nanotechnology extends from its medical, ethical, mental, legal and environmental applications, to fields such as engineering, biology, chemistry, computing, materials science, and communications.
Dean Ho is a Provost's Chair Professor in the Departments of Biomedical Engineering and Pharmacology, Director of the N.1 Institute for Health, and Head of the Department of Biomedical Engineering at the National University of Singapore. He was previously a professor at UCLA, and associate professor in the Departments of Biomedical Engineering and Mechanical Engineering in the Robert R. McCormick School of Engineering and Applied Science, and Full Member of the Robert H. Lurie Comprehensive Cancer Center at the Feinberg School of Medicine of Northwestern University, Illinois, United States.
The following outline is provided as an overview of and topical guide to nanotechnology:
Chad Alexander Mirkin is an American chemist. He is the George B. Rathmann professor of chemistry, professor of medicine, professor of materials science and engineering, professor of biomedical engineering, and professor of chemical and biological engineering, and director of the International Institute for Nanotechnology and Center for Nanofabrication and Molecular Self-Assembly at Northwestern University.
Nanodiamonds, or diamond nanoparticles, are diamonds with a size below 100 nanometers. They can be produced by impact events such as an explosion or meteoritic impacts. Because of their inexpensive, large-scale synthesis, potential for surface functionalization, and high biocompatibility, nanodiamonds are widely investigated as a potential material in biological and electronic applications and quantum engineering.
Younan Xia is a Chinese-American chemist, materials scientist, and bioengineer. He is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering, with joint appointments in the School of Chemistry & Biochemistry, the School of Chemical & Biomolecular Engineering, and Parker H. Petit Institute for Bioengineering & Bioscience at the Georgia Institute of Technology.
The applications of nanotechnology, commonly incorporate industrial, medicinal, and energy uses. These include more durable construction materials, therapeutic drug delivery, and higher density hydrogen fuel cells that are environmentally friendly. Being that nanoparticles and nanodevices are highly versatile through modification of their physiochemical properties, they have found uses in nanoscale electronics, cancer treatments, vaccines, hydrogen fuel cells, and nanographene batteries.
Hadiyah-Nicole Green (1981) is an American medical physicist, known for the development of a method using laser-activated nanoparticles as a potential cancer treatment. She is one of 66 black women to earn a Ph.D. in physics in the United States between 1973 and 2012, and is the second black woman and the fourth black person ever to earn a doctoral degree in physics from The University of Alabama at Birmingham.
Mauro Ferrari is a nanoscientist and leader in the field of nanomedicine. He served as special expert on nanotechnology for the National Cancer Institute (2003-2005) and was instrumental in establishing the Alliance for Nanotechnology in Cancer in 2004. On 1 January 2020, Ferrari was made president of the European Research Council (ERC). Following a vote of no confidence, on 27 March 2020, "all 19 active members of the ERC’s Scientific Council individually and unanimously requested that Mauro Ferrari resign from his position as ERC’s President", due to poor conduct in office, exploiting the position to further his own projects, and for consistently failing to represent the interests of the ERC. On 7 April 2020, Ferrari officially resigned, stating to the media that he was "extremely disappointed by the European response” to the pandemic and expressing frustration over opposition to his efforts to launch a scientific program to combat the virus.
Jessica O. Winter is an American bioengineer. She is a Professor of Chemical, Biomolecular, and Biomedical Engineering and an Associate Director of the MRSEC Center for Emergent Materials at the Ohio State University. Her research interests include nanoparticles for cancer imaging, diagnostics, and drug delivery; and cell migration in the brain tumor microenvironment. In 2021, she was elected a fellow of the American Association for the Advancement of Science, American Institute for Medical and Biological Engineering, Biomedical Engineering Society, and Royal Society of Chemistry.
Ashok M. Raichur is an Indian materials scientist, nanotechnologist and a professor at the Department of Materials Engineering of the Indian Institute of Science, Bangalore. Known for his studies on the use of nanotechnology for biomedical and environmental applications, Raichur is a former Alexander von Humboldt Fellow and a life member of the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2009.
Nanoinformatics is the application of informatics to nanotechnology. It is an interdisciplinary field that develops methods and software tools for understanding nanomaterials, their properties, and their interactions with biological entities, and using that information more efficiently. It differs from cheminformatics in that nanomaterials usually involve nonuniform collections of particles that have distributions of physical properties that must be specified. The nanoinformatics infrastructure includes ontologies for nanomaterials, file formats, and data repositories.
Thomas J. Webster is an American biomedical engineer, researcher, and entrepreneur. Throughout his over 25-year academic career, his research group has produced several books and book chapters. He has over 1350 publications and has an H-index of 118. This high H-index places him amongst the top 1% of researchers in his field.
Hamid Ghandehari is an Iranian-American drug delivery research scientist, and a professor in the Departments of Pharmaceutics and Pharmaceutical Chemistry and Biomedical Engineering at the University of Utah. His research is focused in recombinant polymers for drug and gene delivery, nanotoxicology of dendritic and inorganic constructs, water-soluble polymers for targeted delivery and poly(amidoamine) dendrimers for oral delivery.
Joy Wolfram is a Finnish nanoscientist. She is known for her pioneering work in nanomedicine concerning the treatment of cancer, cardiovascular diseases and other life-threatening illnesses. She is an Associate Professor at the University of Queensland, in the school of Chemical Engineering and the Australian Institute for Bioengineering and Nanotechnology. She was the forefront of the Extracellular Vesicles and Nanomedicine laboratory at Mayo Clinic. She is also an affiliate faculty member at Houston Methodist Hospital's Department of Nanomedecine. Wolfram sits as a scientific advisor and as a board member of several biotechnology companies around the world.
Nicole F. Steinmetz is a German–American biomedical engineer. She is a Full Professor in Biomaterials at the University of California, San Diego and Founding Director of the Center for Nano-ImmunoEngineering (nanoIE). Her research earned her Fellowship nominatioons from the American Institute for Medical and Biological Engineering, Biomedical Engineering Society, and National Academy of Inventors. Steinmetz uses various plant viruses to assist with drug delivery, molecular imaging, and vaccines.
Dipanjan Pan is an Indian American academic who is the Dorothy Foehr Huck & J. Lloyd Huck Chair Professor in Nanomedicine at Pennsylvania State University.
