Ambika Bumb

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Ambika Bumb
Ambika Bumb.jpg
Alma mater University of Oxford (PhD)
Georgia Institute of Technology (BME)
Occupations
  • CEO
  • Engineer
  • Scientist
OrganizationBikanta
Honors Marshall Scholar

Ambika Bumb is an American biomedical scientist and businessperson. [1] Bumb is a nanomedicine specialist who uses nanotechnology for the detection and treatment of disease. As a postdoctoral researcher at the National Cancer Institute and the National Heart, Lung, and Blood Institute, Bumb made new discoveries with nanodiamonds which led to the launch of the biotech Bikanta. [2] [3] Bumb is currently the Deputy Executive Director at the Bipartisan Commission on Biodefense. [4]

Contents

Early life

Bumb was born to Indian Jain parents who immigrated to the United States in pursuit of higher education. Her father was the first in his family to complete his Doctor of Philosophy degree. Her mother the first woman to get her college degree in a STEM field in her town. Her maternal grandfather was a veterinarian.[ citation needed ] Bumb graduated from Southside High School as valedictorian in 2002. [5]

Education

Bumb graduated in 2005 with a Bachelor of Science in Biomedical Engineering and a Minor in Economics from Georgia Institute of Technology. During her undergraduate career, Bumb was recognized with the Helen E. Grenga Outstanding Woman Engineer and the E. Jo Baker President's Scholar Awards. [6] She conducted research focused on tracking quantum dots in bone and cartilage while also being an active leader in various campus organizations. [7]

In 2008, Bumb completed her Doctorate in Medical Engineering in three years from University of Oxford while also on the Marshall Scholarship and NIH-OxCam Program. [8] [9] She developed a triple-reporting nanoparticle and showed the technology's transferability across different disease types, including cancer and multiple sclerosis. The magnetic nanoparticles demonstrated strong potential in cancer diagnostics and therapy. [8] [10] Upon graduation, she continued on to two post-doctoral fellowships at the National Cancer Institute (2009-2011) and National Heart, Lung and Blood Institute (2011-2013).[ citation needed ]

Career

Her breakthroughs in the areas of nanomedicine and diagnostics have led to multiple patents, publications. Bumb also founded her own biotech company, Bikanta[ citation needed ], which uses nanodiamonds to allow academics and doctors to study and address disease at the cellular level. Bikanta was among the early biotechnology startups to receive funding from Y Combinator, and was a recipient of the California Life Science Institute's FAST Award, and named 1 of 4 Best Diagnostics Startups of 2015 by QB3. [11]

As Bikanta prepared to move the technology into clinical trials, the Theranos scandal went public and many investors pulled out of the diagnostics space. [12] Bikanta was unable to raise the funding to proceed with the clinical trials. [13]

Complementary to her scientific and commercial interests, Bumb has also been involved in national science policy initiatives, particularly related to nanotechnology. [14] After Bikanta, Bumb began working as Health Science and Technology Advisor for the Secretary of State in the Office of Crisis Management and Strategy in December 2019, where she played a role in the government response to the COVID-19 pandemic. [13] Later, she transferred to President Joe Biden's Council of Advisors on Science and Technology as Deputy Executive Director. [15] [4]

Awards and recognition

Related Research Articles

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<span class="mw-page-title-main">Nanobiotechnology</span> Intersection of nanotechnology and biology

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<span class="mw-page-title-main">Nanochemistry</span> Combination of chemistry and nanoscience

Nanochemistry is an emerging sub-discipline of the chemical and material sciences that deals with the development of new methods for creating nanoscale materials. The term "nanochemistry" was first used by Ozin in 1992 as 'the uses of chemical synthesis to reproducibly afford nanomaterials from the atom "up", contrary to the nanoengineering and nanophysics approach that operates from the bulk "down"'. Nanochemistry focuses on solid-state chemistry that emphasizes synthesis of building blocks that are dependent on size, surface, shape, and defect properties, rather than the actual production of matter. Atomic and molecular properties mainly deal with the degrees of freedom of atoms in the periodic table. However, nanochemistry introduced other degrees of freedom that controls material's behaviors by transformation into solutions. Nanoscale objects exhibit novel material properties, largely as a consequence of their finite small size. Several chemical modifications on nanometer-scaled structures approve size dependent effects.

The impact of nanotechnology extends from its medical, ethical, mental, legal and environmental applications, to fields such as engineering, biology, chemistry, computing, materials science, and communications.

Dean Ho is a Provost's Chair Professor in the Departments of Biomedical Engineering and Pharmacology, Director of the N.1 Institute for Health, and Head of the Department of Biomedical Engineering at the National University of Singapore. He was previously a professor at UCLA, and associate professor in the Departments of Biomedical Engineering and Mechanical Engineering in the Robert R. McCormick School of Engineering and Applied Science, and Full Member of the Robert H. Lurie Comprehensive Cancer Center at the Feinberg School of Medicine of Northwestern University, Illinois, United States.

The following outline is provided as an overview of and topical guide to nanotechnology:

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<span class="mw-page-title-main">Nanodiamond</span> Extremely small diamonds used for their thermal, mechanical and optoelectronic properties

Nanodiamonds, or diamond nanoparticles, are diamonds with a size below 100 nanometers. They can be produced by impact events such as an explosion or meteoritic impacts. Because of their inexpensive, large-scale synthesis, potential for surface functionalization, and high biocompatibility, nanodiamonds are widely investigated as a potential material in biological and electronic applications and quantum engineering.

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Hadiyah-Nicole Green (1981-) is an American medical physicist, known for the development of a method using laser-activated nanoparticles as a potential cancer treatment. She is one of 66 black women to earn a Ph.D. in physics in the United States between 1973 and 2012, and is the second black woman and the fourth black person ever to earn a doctoral degree in physics from The University of Alabama at Birmingham.

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References

  1. Russon, Mary-Ann (August 18, 2014). "Microscopic Diamonds Are Lighting The Way to Early Cancer Detection". International Business Times UK. Retrieved October 31, 2017.
  2. 1 2 "NIH Marshall Scholarships". Marshall Scholarship . Retrieved October 31, 2017.
  3. "All Inventions from Dr. Ambika Bumb". NIH Office of Technology Transfer . Archived from the original on December 15, 2018. Retrieved October 31, 2017.
  4. 1 2 "Ambika Bumb, PhD". Bipartisan Commission on Biodefense. Retrieved March 20, 2024.
  5. Simon, Anna (June 2, 2002). "Clemson's scholarship program lures top scholars". The Greenville News. pp. B.1. Retrieved March 20, 2024.
  6. 1 2 Rich, Walter (May 13, 2016). "Ambika Bumb and Xavier Lefebvre Honored at the College of Engineering Alumni Awards Induction Ceremony". The Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology & Emory University School of Medicine. Archived from the original on July 17, 2020. Retrieved October 31, 2017.
  7. "Marshall Scholarship for Georgia Tech Senior". www.khabar.com. Retrieved March 20, 2024.
  8. 1 2 McCook, Alison (April 20, 2011). "Education: Rethinking PhDs". Nature News. 472 (7343): 280–282. Bibcode:2011Natur.472..280M. doi: 10.1038/472280a . PMID   21512549.
  9. Commemoration., Commission, Marshall Aid (2013). Fifty ninth annual report of the marshall aid commemoration commission for. Tso. p. 25. ISBN   978-0108512209. OCLC   925437833.{{cite book}}: CS1 maint: multiple names: authors list (link)
  10. Vara, Vauhini (August 20, 2014). "Fever Pitch". The New Yorker. Retrieved November 1, 2017.
  11. "Alliance Appoints Alumni Directors Drs. Bumb and Maciejewski – International Biomedical Alliance" . Retrieved June 6, 2023.
  12. Varghese, Sanjana (February 13, 2019). "The spectre of Theranos looms large over the diagnostic world". Wired. Retrieved August 9, 2021.
  13. 1 2 Grant Belgard (March 16, 2021). "Ambika Bumb". The Bioinformatics CRO (Podcast). Retrieved August 9, 2021.
  14. Bumb, Ambika. "A Nano Step For Man, A Giant Leap For Mankind". TechCrunch. Retrieved December 12, 2017.
  15. "Ambika Bumb, BME 05". Georgia Tech Alumni Association. Retrieved March 20, 2024.