BET1L

BET1L
Identifiers
Aliases	BET1L , BET1L1, GOLIM3, GS15, HSPC197, Bet1 golgi vesicular membrane trafficking protein like
External IDs	OMIM: 615417 MGI: 1913128 HomoloGene: 10293 GeneCards: BET1L
Gene location (Human)
Chr.	Chromosome 11 (human)
End	207,399 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	140,437,490 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; anterior pituitary; ; right coronary artery; ; body of stomach; ; gastric mucosa; ; canal of the cervix; ; ascending aorta; ; stromal cell of endometrium; ; popliteal artery; ; right lung;
	Top expressed in
	molar; ; parotid gland; ; seminal vesicula; ; calvaria; ; spermatocyte; ; motor neuron; ; crypt of lieberkuhn of small intestine; ; right lung lobe; ; proximal tubule; ; subcutaneous adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SNAP receptor activity ;
Cellular component	integral component of membrane ; Golgi membrane ; endosome ; Golgi apparatus ; SNARE complex ; membrane ; cytosol ; Golgi trans cisterna ; Golgi stack ; integral component of Golgi membrane ;
Biological process	protein transport ; endoplasmic reticulum to Golgi vesicle-mediated transport ; retrograde transport, endosome to Golgi ; regulation of retrograde vesicle-mediated transport, Golgi to ER ; membrane fusion ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	51272
	54399
	ENSG00000177951
	ENSMUSG00000025484
	Q9NYM9
	O35153
	NM_016526 ; NM_001098787 ; NM_016465
	NM_018742
	NP_001092257 ; NP_057610
	NP_061212
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 03, 2023

BET1-like protein is a protein that in humans is encoded by the BET1L gene.^[5]^[6]^[7]

Interactions

BET1L has been shown to interact with:

Related Research Articles

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Sec1 family domain-containing protein 1 is a protein that in humans is encoded by the SCFD1 gene.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000177951 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025484 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Xu Y, Wong SH, Zhang T, Subramaniam VN, Hong W (Sep 1997). "GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1". J Biol Chem. 272 (32): 20162–6. doi: 10.1074/jbc.272.32.20162 . PMID 9242691.
↑ Oka T, Ungar D, Hughson FM, Krieger M (Apr 2004). "The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins". Mol Biol Cell. 15 (5): 2423–35. doi:10.1091/mbc.E03-09-0699. PMC 404034 . PMID 15004235.
↑ "Entrez Gene: BET1L blocked early in transport 1 homolog (S. cerevisiae)-like".
1 2 3 Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G (Apr 2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. 157 (1): 45–62. doi:10.1083/jcb.200112127. PMC 2173270 . PMID 11927603.
1 2 3 Xu Y, Martin S, James DE, Hong W (Oct 2002). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961 . PMID 12388752.

External links

Human BET1L genome location and BET1L gene details page in the UCSC Genome Browser .

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152.
Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. Bibcode:2001Sci...291.1304V. doi:10.1126/science.1058040. PMID 11181995.
Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport". J. Biol. Chem. 276 (29): 27480–7. doi: 10.1074/jbc.M102786200 . PMID 11323436.
Shorter J, Beard MB, Seemann J, et al. (2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. 157 (1): 45–62. doi:10.1083/jcb.200112127. PMC 2173270 . PMID 11927603.
Xu Y, Martin S, James DE, Hong W (2003). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961 . PMID 12388752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Tai G, Lu L, Wang TL, et al. (2005). "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network". Mol. Biol. Cell. 15 (9): 4011–22. doi:10.1091/mbc.E03-12-0876. PMC 515336 . PMID 15215310.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000177951 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025484 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9242691-5] Xu Y, Wong SH, Zhang T, Subramaniam VN, Hong W (Sep 1997). "GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1". J Biol Chem. 272 (32): 20162–6. doi: 10.1074/jbc.272.32.20162 . PMID 9242691.

[pmid15004235-6] Oka T, Ungar D, Hughson FM, Krieger M (Apr 2004). "The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins". Mol Biol Cell. 15 (5): 2423–35. doi:10.1091/mbc.E03-09-0699. PMC 404034 . PMID 15004235.

[entrez-7] "Entrez Gene: BET1L blocked early in transport 1 homolog (S. cerevisiae)-like".

[pmid11927603-8] 1 2 3 Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G (Apr 2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. 157 (1): 45–62. doi:10.1083/jcb.200112127. PMC 2173270 . PMID 11927603.

[pmid12388752-9] 1 2 3 Xu Y, Martin S, James DE, Hong W (Oct 2002). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961 . PMID 12388752.

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BET1L

Contents

Interactions

Related Research Articles

References

External links

Further reading