Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene. [5] [6] [7]
BRD7 has been shown to interact with IRF2 [8] and HNRPUL1. [9]
BRD7 protein is a transcription regulator that is normally highly expressed in the testis, particularly in meiotic pachytene and diplotene spermatocytes and in round spermatids. However, in the testes of patients exhibiting spermatogenesis arrest and azoospermia, BRD7 protein expression is observed to be absent or reduced. [10] Homozygous knockout mice [BRD7(-/-)] are infertile and have increased DNA damage and apoptosis in their germline. [10]
Histone H4 is a protein that in humans is encoded by the HIST4H4 gene.
Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.
Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene.
AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene.
Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also contains BRD3, BRD4, and BRDT in mammals
Histone H2B type 3-B is a protein that in humans is encoded by the HIST3H2BB gene.
Heterogeneous nuclear ribonucleoprotein U-like protein 1 is a protein that in humans is encoded by the HNRNPUL1 gene.
Nucleosome-remodeling factor subunit BPTF is a protein that in humans is encoded by the BPTF gene.
Transgelin is a protein that in humans is encoded by the TAGLN gene.
Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.
Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.
Cyclin-T2 is a protein that in humans is encoded by the CCNT2 gene.
Krueppel-like factor 10 is a protein that in humans is encoded by the KLF10 gene.
Protein kinase C-binding protein 1 is an enzyme that in humans is encoded by the ZMYND8 gene.
Sodium- and chloride-dependent taurine transporter is a protein that in humans is encoded by the SLC6A6 gene.
Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene.
Zinc finger protein OZF is a protein that in humans is encoded by the ZNF146 gene.
Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AL gene.
Bromodomain-containing protein 3 (BRD3) also known as RING3-like protein (RING3L) is a protein that in humans is encoded by the BRD3 gene. This gene was identified based on its homology to the gene encoding the RING3 (BRD2) protein, a serine/threonine kinase. The gene maps to 9q34, a region which contains several major histocompatibility complex (MHC) genes.
E74-like factor 2 (ELF2), formerly known as new Ets-related factor (NERF), is an ETS family transcription factor. In humans this protein is encoded by the ELF2 gene.