Brain, Behavior, and Immunity

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Mind–body interventions (MBI) or mind-body training (MBT) are health and fitness interventions that are intended to work on a physical and mental level such as yoga, tai chi, and Pilates.

Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI) or psychoneuroendocrinoimmunology (PNEI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. It is a subfield of psychosomatic medicine. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.

Neuroimmunology is a field combining neuroscience, the study of the nervous system, and immunology, the study of the immune system. Neuroimmunologists seek to better understand the interactions of these two complex systems during development, homeostasis, and response to injuries. A long-term goal of this rapidly developing research area is to further develop our understanding of the pathology of certain neurological diseases, some of which have no clear etiology. In doing so, neuroimmunology contributes to development of new pharmacological treatments for several neurological conditions. Many types of interactions involve both the nervous and immune systems including the physiological functioning of the two systems in health and disease, malfunction of either and or both systems that leads to disorders, and the physical, chemical, and environmental stressors that affect the two systems on a daily basis.

Genes, Brain and Behavior is a peer-reviewed scientific journal covering research in the fields of behavioral, neural, and psychiatric genetics. It is published by Wiley-Blackwell on behalf of the International Behavioural and Neural Genetics Society. The journal was established in 2002 as a quarterly and is currently published monthly. G2B is a hybrid open access journal, but two years after publication all content is available for free online.

<span class="mw-page-title-main">Gary Berntson</span>

Gary Berntson is an emeritus professor at Ohio State University with appointments in the departments of psychology, psychiatry and pediatrics. He is an expert in psychophysiology, neuroscience, biological psychology, and with his colleague John Cacioppo, a founding father of social neuroscience. His research attempts to elucidate the functional organization of brain mechanisms underlying behavioral and affective processes, with a special emphasis on social cognition.

Neural top–down control of physiology concerns the direct regulation by the brain of physiological functions. Cellular functions include the immune system’s production of T-lymphocytes and antibodies, and nonimmune related homeostatic functions such as liver gluconeogenesis, sodium reabsorption, osmoregulation, and brown adipose tissue nonshivering thermogenesis. This regulation occurs through the sympathetic and parasympathetic system, and their direct innervation of body organs and tissues that starts in the brainstem. There is also a noninnervation hormonal control through the hypothalamus and pituitary (HPA). These lower brain areas are under control of cerebral cortex ones. Such cortical regulation differs between its left and right sides. Pavlovian conditioning shows that brain control over basic cell level physiological function can be learned.

<i>Physiology & Behavior</i> Academic journal

Physiology & Behavior is a peer-reviewed scientific journal published by Elsevier. It covers the fields of behavioral neuroendocrinology, psychoneuroimmunology, learning and memory, ingestion, social behavior, and studies related to the mechanisms of psychopathology. It was established in 1966 with Matthew J. Wayner as its founding editor-in-chief. The current editor-in-chief is Thomas Lutz.

Guided imagery is a mind-body intervention by which a trained practitioner or teacher helps a participant or patient to evoke and generate mental images that simulate or recreate the sensory perception of sights, sounds, tastes, smells, movements, and images associated with touch, such as texture, temperature, and pressure, as well as imaginative or mental content that the participant or patient experiences as defying conventional sensory categories, and that may precipitate strong emotions or feelings in the absence of the stimuli to which correlating sensory receptors are receptive.

<i>Brain Research</i> Academic journal

Brain Research is a peer-reviewed scientific journal focusing on several aspects of neuroscience. It publishes research reports and "minireviews". The editor-in-chief is Matthew J. LaVoie.

David L. Felten is an American neuroscientist. He is associate dean of clinical sciences at the University of Medicine and Health Sciences, and was formerly associate dean of research at Oakland University and vice president for research and medical director of the Beaumont Research Institute.

Robert Ader was an American psychologist and academic who co-founded psychoneuroimmunology, a field of study which explores the links connecting the brain, behavior, and the immune system. Ader was a professor emeritus at the University of Rochester Medical Center.

<span class="mw-page-title-main">Vijendra K. Singh</span> Neuroimmunologist

Vijendra Kumar Singh is a neuroimmunologist who formerly held a post at Utah State University, prior to which he was a professor at the University of Michigan. While affiliated with both institutions, he conducted some controversial autism-related research focusing on the potential role of immune system disorders in the etiology of autism. For example, he has testified before a US congressional committee that, in his view, "three quarters of autistic children suffer from an autoimmune disease."

<span class="mw-page-title-main">Raz Yirmiya</span>

Raz Yirmiya is an Israeli behavioral neuroscientist and director of the Laboratory for Psychoneuroimmunology at the Hebrew University of Jerusalem in Israel. He is best known for providing the first experimental evidence for the role of immune system activation in depression, for discovering that disturbances in brain microglia cells underlie some forms of depression, and for elucidating the involvement of inflammatory cytokines in regulation of cognitive and emotional processes.

Audio therapy is the clinical use of recorded sound, music, or spoken words, or a combination thereof, recorded on a physical medium such as a compact disc (CD), or a digital file, including those formatted as MP3, which patients or participants play on a suitable device, and to which they listen with intent to experience a subsequent beneficial physiological, psychological, or social effect.

Immuno-psychiatry, according to Pariante, is a discipline that studies the connection between the brain and the immune system. It differs from psychoneuroimmunology by postulating that behaviors and emotions are governed by peripheral immune mechanisms. Depression, for instance, is seen as malfunctioning of the immune system.

<span class="mw-page-title-main">Jonathan Kipnis</span> Neuroscientist

Jonathan Kipnis is a neuroscientist, immunologist, and professor of pathology and immunology at the Washington University School of Medicine. His lab studies interactions between the immune system and nervous system. He is best known for his lab's discovery of meningeal lymphatic vessels in humans and mice, which has impacted research on neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis, neuropsychiatric disorders, such as anxiety, and neurodevelopmental disorders such as autism and Rett syndrome.

<span class="mw-page-title-main">Janice Kiecolt-Glaser</span> American psychiatrist

Janice K Kiecolt-Glaser is S. Robert Davis Chair of Medicine and Distinguished University Professor at the Ohio State University College of Medicine. She is a clinical health psychologist specializing in psychoneuroimmunology and Director of the Ohio State Institute for Behavioral Medicine Research. Her research on stress associated with caregiving and marital relationships has been featured in The New York Times, The Wall Street Journal, and many other news outlets.

<span class="mw-page-title-main">Keith W. Kelley</span> American immunophysiologist, researcher and academic

Keith Kelley is an American immunophysiologist, researcher and academic. He is Professor Emeritus of Immunophysiology at the University of Illinois and Editor-In-Chief Emeritus of Brain, Behavior, and Immunity. He is a Past-President and Secretary-Treasurer of the Psychoneuroimmunology Research Society.

<span class="mw-page-title-main">Staci Bilbo</span> American neuroimmunologist

Staci Bilbo is an American neuroimmunologist and The Haley Family Professor of Psychology and Neuroscience at Duke University. Bilbo also holds a position as a research affiliate at Massachusetts General Hospital overseeing research within the Lurie Center for Autism. As the principal investigator of the Bilbo Lab, Bilbo investigates how environmental challenges during the perinatal period impact the immune system and further influence brain development, cognition, and affective behaviors later in life..

Aaron Frederick "Fred" Rasmussen Jr. was an American physician, professor of microbiology and immunology, and, later in his career, associate dean of the UCLA School of Medicine. He is known for his pioneering research in psychoneuroimmunology.

References

  1. "Robert Ader, Founder of Psychoneuroimmunology, Dies". University of Rochester. 20 December 2011. Retrieved 3 December 2014.
  2. "Brain, Behavior, and Immunity". 2021 Journal Citation Reports. Web of Science (Science ed.). Clarivate Analytics. 2021.