Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin.
Mammography is the process of using low-energy X-rays to examine the human breast for diagnosis and screening. The goal of mammography is the early detection of breast cancer, typically through detection of characteristic masses or microcalcifications.
Cancer Cell is a peer-reviewed scientific journal scientific journal that publishes articles that provide major advances in cancer research and oncology. The journal considers manuscripts that answer important questions relevant to naturally occurring cancers. Areas covered include basic cancer biology, therapeutic development, translational research, cancer model development, multi-omics and computational biology. Cancer Cell is also interested in publishing clinical investigations, in particular those that lead to establishing new paradigms in the treatment, diagnosis, or prevention of cancers; those that provide important insights into cancer biology beyond what has been revealed by preclinical studies; and those that are mechanism-based proof-of-principle clinical studies.
Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome. Tamoxifen is typically taken daily by mouth for five years for breast cancer.
Bevacizumab, sold under the brand name Avastin among others, is a medication used to treat a number of types of cancers and a specific eye disease. For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, glioblastoma, and renal-cell carcinoma. In many of these diseases it is used as a first-line therapy. For age-related macular degeneration it is given by injection into the eye (intravitreal).
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and treatment of cancer. Founded in 1907 by 11 physicians and scientists, the organization now has more than 52,000 members in 130 countries and territories. The mission of the AACR is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research.
Adjuvant therapy, also known as adjunct therapy, adjuvant care, or augmentation therapy, is a therapy that is given in addition to the primary or initial therapy to maximize its effectiveness. The surgeries and complex treatment regimens used in cancer therapy have led the term to be used mainly to describe adjuvant cancer treatments. An example of such adjuvant therapy is the additional treatment usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due to the presence of undetected disease. If known disease is left behind following surgery, then further treatment is not technically adjuvant.
Cancer Research is a biweekly peer-reviewed medical journal published by the American Association for Cancer Research. It covers research on all aspects of cancer and cancer-related biomedical sciences and was established in 1941. The editor-in-chief is Chi Van Dang.
Integrative Cancer Therapies is a peer-reviewed medical journal focusing on complementary and alternative and integrative medicine in the care for and treatment of patients with cancer. Therapies like diets and lifestyle modifications, as well as experimental vaccines and chemotherapy are the subject of this journal. It was established in 2002 and is published by SAGE Publications. The editor-in-chief is Keith I. Block.
The International Journal of Cancer is a biweekly peer-reviewed medical journal covering experimental and clinical cancer research. It publishes original research articles, mini reviews, short reports, and letters to the editor. The journal was established in 1966 and is published by John Wiley & Sons on behalf of the Union for International Cancer Control. The editor-in-chief is Christoph Plass. According to the Journal Citation Reports, the journal has a 2020 impact factor of 7.396.
Clinical Cancer Research is a peer-reviewed medical journal on oncology, including the cellular and molecular characterization, prevention, diagnosis, and therapy of human cancer, medical and hematological oncology, radiation therapy, pediatric oncology, pathology, surgical oncology, and clinical genetics. The applications of the disciplines of pharmacology, immunology, cell biology, and molecular genetics to intervention in human cancer are also included. One of the main interests of Clinical Cancer Research is on clinical trials that evaluate new treatments together with research on pharmacology and molecular alterations or biomarkers that predict response or resistance to treatment. Another priority for Clinical Cancer Research is laboratory and animal studies of new drugs as well as molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype, and metastatic disease. The journal is published by the American Association for Cancer Research.
The European Journal of Cancer is a peer-reviewed medical journal devoted to cancer research on experimental oncology, clinical oncology, and on cancer epidemiology and prevention. It is the official journal of the European Organisation for Research and Treatment of Cancer (EORTC) and the European Society of Breast Cancer Specialists (EUSOMA). The editor-in-chief is Alexander M. M. Eggermont.
David Henry Gorski is an American surgical oncologist and professor of surgery at Wayne State University School of Medicine. He specializes in breast cancer surgery at the Karmanos Cancer Institute. Gorski is an outspoken skeptic and critic of alternative medicine and the anti-vaccination movement. A prolific blogger, he writes as Orac at Respectful Insolence, and as himself at Science-Based Medicine where he is the managing editor.
Rajendra Achyut Badwe, is an Indian medical doctor and surgical oncologist. He was honoured by the Government of India, in 2013, by bestowing on him the Padma Shri, the fourth highest civilian award, for his contributions to the field of medicine.
Breast Cancer Research is a bimonthly peer-reviewed medical journal covering research into breast cancer. The journal was established in 1999 and is published by BioMed Central. The editor-in-chief is Lewis Chodosh.
Endocrine-Related Cancer is a monthly peer-reviewed medical journal covering cancers in endocrine organs — such as the breast, prostate, pituitary, testes, ovaries, and neuroendocrine system — and hormone-dependent cancers occurring elsewhere in the body. Its scope covers basic, translational, clinical and experimental studies.
Patricia Anne Ganz is an American medical oncologist. She is a professor of health policy and management in the Fielding School of Public Health and a professor of medicine in the David Geffen School of Medicine at UCLA. In 2007, she was elected to the Institute of Medicine.
Sherene Loi is an Australian oncologist. She is the 2021 winner of the Australian Prime Ministers Prize for Science, in the category of Frank Fenner Prize for Life Scientist of the Year. Loi is Head of Translational Breast Cancer Research, within the Peter Macallum Cancer Centre. Loi's research has advanced understanding into breast cancer, developing and implementing an immune system biomarker. This biomarker will enable improved management for people with advanced cancer. This biomarker is now part of routine pathology reporting across many countries and also is included in the World Health Organisation Classification of Tumours.
