| Brisavirus | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cressdnaviricota |
| Class: | Arfiviricetes |
| Order: | Recrevirales |
| Family: | Redondoviridae |
| Genus: | Torbevirus |
| Species: | Torbevirus brisa |
Brisavirus (isolate LC KY052047) is a species of viruses in the family Redondoviridae in the genus Torbevirus . [1] Brisa- is from the Spanish word for "Breeze", which refers to their isolation from the human respiratory tract. It was discovered in a throat swab in a male traveler who presented with fever, enlarged adenoids, flushed skin and myalgia after testing negative for other viruses. [2] Brisavirus like other viruses in the Redondoviridae family, are present and putatively replicate in the oro-respiratory tract. [3] They are associated in patients with critical illness and periodontitis. [3]
Brisavirus has a CRESS DNA genome with 3 open reading frames that are inversely oriented that encode for the capsid and Replication-associated protein protein with a small and larger intergenic region. [4] They replicate using rolling-circle replication like other CRESS viruses. [4] By using metagenomic analysis, researchers found that the encoded proteins were most similar to porcine stool-associated circular virus 5 isolate CP33 (PoSCV5). [2] [3]