| Location | |
|---|---|
| Country | United States | 
| Highway system | |
Interstate business routes are roads connecting a central or commercial district of a city or town with an Interstate bypass. These roads typically follow along local streets often along a former U.S. Route or state highway that had been replaced by an Interstate. Interstate business route reassurance markers are signed as either loops or spurs using a green shield shaped sign and numbered like the shield of the parent Interstate highway.
Along Interstate 55 (I-55), there are a total of six business routes, three in both Missouri and Illinois, all which are business loops.
| Location | New Madrid, MO | 
|---|---|
| Length | 5.7 mi [1] (9.2 km) | 
Interstate 55 Business (I-55 Bus.) is a major arterial surface street that serves downtown New Madrid, Missouri. It runs north from I-55 at exit 44 and the overlap of U.S. Route 61 (US 61)/US 62 through downtown to exit 49 on I-55.
The entire route is in New Madrid County.
| Location | mi [1] | km | Destinations | Notes | |
|---|---|---|---|---|---|
| New Madrid | 0.0 | 0.0 | Southern terminus of BL 55; southern end on US 61 and US 62 concurrencies | ||
| 3.1 | 5.0 | ||||
|  | 5.7 | 9.2 | Northern terminus of BL 55; northern end on US 61 and US 62 concurrencies | ||
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi | |||||
|   | This section needs expansion. You can help by adding to it.  (May 2025)  | 
| Location | Cape Girardeau–Fruitland, MO | 
|---|---|
Interstate 55 Business (I-55 Bus.) begins at US 61/Route 74 in Cape Girardeau at exit 93 and ends at US 61 at exit 105 in Fruitland. However, it also crosses its parent Interstate at exit 99
|   | This section needs expansion. You can help by adding to it.  (May 2025)  | 
| Location | Crystal City–Herculaneum, MO | 
|---|---|
Interstate 55 Business (I-55 Bus.) spans from US 67/US 61 at exit 174 in Crystal City to McNutt Street at exit 178 in Herculaneum.
| Location | Springfield – Sherman, IL | 
|---|---|
| Length | 13.9 mi [2] (22.4 km) | 
Interstate 55 Business (I-55 Bus.) is to a major arterial surface street that serves downtown Springfield, Illinois. It runs north from the intersection of I-55 and I-72 through downtown to Illinois Route 4 (IL 4, Veterans' Parkway). It then runs northeast to Sherman. [3]
All of I-55 Bus. was part of US 66 at some point.[ citation needed ]
Major intersections
 The entire route is in Sangamon County.
| Location | mi [2] | km | Destinations | Notes | |
|---|---|---|---|---|---|
| Springfield | 0.0– 0.7  | 0.0– 1.1  | Exit 92A (I-55), Exit 97B (I-72) | ||
| 4.9 | 7.9 | ||||
| 5.0 | 8.0 | ||||
| 7.0 | 11.3 | Southern end of IL 29 concurrency | |||
| 8.0 | 12.9 | Northern end of IL 29 concurrency, northern terminus of IL 4 | |||
| Sherman | 12.1 | 19.5 | Eastern terminus of IL 124 | ||
| 12.7 | 20.4 | Exit 105 (I-55), no access to I-55 northbound from this point | |||
| 13.9 | 22.4 | Only access to I-55 northbound | |||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
  | |||||
| Location | Lincoln, IL | 
|---|---|
Interstate 55 Business (I-55 Bus.) services the downtown of Lincoln, Illinois.
Major intersections
 The entire route is in Logan County.
| Location | mi | km | Destinations | Notes | |
|---|---|---|---|---|---|
| Broadwell Township | 0.0 | 0.0 | Southern terminus, I-55 exit 123 | ||
| Lincoln | 3.4 | 5.5 | |||
| 5.0 | 8.0 | Western end of IL 10/IL 121 concurrency | |||
| 5.2 | 8.4 | Eastern end of IL 10/IL 121 concurrency | |||
| 7.1 | 11.4 | ||||
| 7.5 | 12.1 | ||||
| East Lincoln Township | 8.9 | 14.3 | Northern terminus, I-55 exit 133 | ||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
  | |||||
| Location | Bloomington–Normal, IL | 
|---|---|
Interstate 55 Business (I-55 Bus.) in Bloomington–Normal is known for its entire length as Veterans Parkway. It is a divided, limited-access highway bypassing the Bloomington–Normal area to the south and east. The route's north–south portion largely passes through a retail core, including Eastland Mall and The Shoppes at College Hills. The highway is also the recommended route from I-39, I-55, and I-74 to Central Illinois Regional Airport via IL 9.
Major intersections
This section is missing mileposts for junctions.  | 
The entire route is in McLean County.
| Location | mi | km | Destinations | Notes | |
|---|---|---|---|---|---|
| Bloomington | 0.0 | 0.0 | Exit 157 on I-55; exit 134 on westbound I-74 | ||
| Interchange | |||||
| Central Illinois Regional Airport | |||||
| Normal | Southbound exit only | ||||
| I-55 exit 167; road continues to the north as Pipeline Road | |||||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
  | |||||