| CLEC16A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | CLEC16A , Gop-1, KIAA0350, C-type lectin domain family 16 member A, C-type lectin domain containing 16A | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611303 MGI: 1921624 HomoloGene: 71019 GeneCards: CLEC16A | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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C-type lectin domain family 16, also known as CLEC16A, is a protein that in humans is encoded by the CLEC16A gene. [5] [6] [7]
Little is known regarding the function of the CLEC16A protein, however it is shown to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. Despite its name CLEC16A may not function as a lectin because its C-type lectin domain is only 20 amino-acids long. [8]
Polymorphisms in the CLEC16A gene are associated with an increased risk of multiple sclerosis [9] as well as type I diabetes. [8]
Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in the Alzheimer's disease and cardiovascular diseases. It is encoded in humans by the gene APOE.
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Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.
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