 | |
| Discipline | Oncology |
|---|---|
| Language | English |
| Edited by | M. Schwab |
| Publication details | |
| History | 1975-present |
| Publisher | |
| Frequency | 28/year |
| 9.756 (2021) | |
| Standard abbreviations | |
| ISO 4 | Cancer Lett. |
| Indexing | |
| CODEN | CALEDQ |
| ISSN | 0304-3835 (print) 1872-7980 (web) |
| LCCN | 77640685 |
| OCLC no. | 1874893 |
| Links | |
Cancer Letters is a peer-reviewed medical journal established in 1975 that focuses on the rapid publication of original research on multidisciplinary aspects of cancer. The editor-in-chief is M. Schwab.
Cancer Letters is abstracted and indexed in BIOSIS, Chemical Abstracts, Current Contents/Life Sciences, EMBASE, MEDLINE, Oncology Information Service, PASCAL and FRANCIS, and Scopus.
  | This article about an oncology journal is a stub. You can help Wikipedia by expanding it. See tips for writing articles about academic journals. Further suggestions might be found on the article's talk page. |
A Bayer designation is a stellar designation in which a specific star is identified by a Greek or Latin letter followed by the genitive form of its parent constellation's Latin name. The original list of Bayer designations contained 1,564 stars. The brighter stars were assigned their first systematic names by the German astronomer Johann Bayer in 1603, in his star atlas Uranometria. Bayer catalogued only a few stars too far south to be seen from Germany, but later astronomers supplemented Bayer's catalog with entries for southern constellations.
Heme, or haem, is a ring-shaped iron-containing molecular component of hemoglobin, which is necessary to bind oxygen in the bloodstream. It is composed of four pyrrole rings with 2 vinyl and 2 propionic acid side chains. Heme is biosynthesized in both the bone marrow and the liver.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans.
Malignancy is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer.
Frank Eugene "Hill" Harper is an American actor and political candidate. He is known for his roles as Dr. Sheldon Hawkes in CSI: NY, Agent Spelman Boyle in Limitless, and Dr. Marcus Andrews in The Good Doctor.
In the field of machine learning and specifically the problem of statistical classification, a confusion matrix, also known as error matrix, is a specific table layout that allows visualization of the performance of an algorithm, typically a supervised learning one; in unsupervised learning it is usually called a matching matrix.
Bessie Lillian Carter was an American nurse. Carter's son, Jimmy Carter, served as the 39th president of the United States from 1977 to 1981. She was also known for her contributions as a Peace Corps volunteer in India and for writing two books during her son’s presidency.
alpha Kappa Delta Phi (αΚΔΦ), also known as aKDPhi, Kappa Delta Phi, KDPhi, is an international Asian-interest sorority founded at the University of California, Berkeley. alpha Kappa Delta Phi has established 67 chapters and colonies at numerous universities across the United States and in Canada. It is part of the National APIDA Panhellenic Association (NAPA), which it helped charter in 2006.
Zbtb7, whose protein product is also known as Pokemon, is a gene that functions as a regulator of cellular growth and a proto oncogene.
Vindesine, also termed Eldisine, is a semisynthetic vinca alkaloid derived from the flowering plant Catharanthus roseus. Like the natural and semisynthetic vinca alkaloids derived from this plant, vindesine is an inhibitor of mitosis that is used as a chemotherapy drug. By inhibiting mitosis, vinedsine blocks the proliferation of cells, particularly the rapidly proliferation cells of certain types of cancer. It is used, generally in combination with other chemotherapeutic drugs, in the treatment of various malignancies such as leukaemia, lymphoma, melanoma, breast cancer, and lung cancer.
Homeobox protein MOX-2 is a protein that in humans is encoded by the MEOX2 gene.
TOX high mobility group box family member 3, also known as TOX3, is a human gene.
Elsamitrucin is a drug used in chemotherapy. Elsamitrucin is chemically related to chartreusin.
Letters to God is a 2010 American Christian drama film directed by David Nixon and starring Robyn Lively, Jeffrey Johnson, Tanner Maguire, Michael Bolten and Bailee Madison. The story was written by Patrick Doughtie about his son Tyler, with the screenplay penned by Doughtie, Art D'Alessandro, Sandra Thrift and Cullen Douglas. The story took place in Nashville, Tennessee, but the movie was filmed in Orlando, Florida.
Black salve, also known by the brand name Cansema, is an ineffective and unsafe alternative cancer treatment. The product is commonly classified as an escharotic—a topical paste which destroys skin tissue and leaves behind a scar called an eschar. Escharotics were widely used to treat skin lesions in the early 1900s, but have since been replaced by safer and more effective treatments. Escharotics, such as black salves, are currently advertised by some alternative medicine marketers as treatments for skin cancer, often with unsubstantiated testimonials and unsupported claims of effectiveness.
Seviteronel is an experimental cancer medication which is under development by Viamet Pharmaceuticals and Innocrin Pharmaceuticals for the treatment of prostate cancer and breast cancer. It is a nonsteroidal CYP17A1 inhibitor and works by inhibiting the production of androgens and estrogens in the body. As of July 2017, seviteronel is in phase II clinical trials for both prostate cancer and breast cancer. In January 2016, it was designated fast-track status by the United States Food and Drug Administration for prostate cancer. In April 2017, seviteronel received fast-track designation for breast cancer as well.
Epacadostat is an investigational drug for cancer. Epacadostat is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1). Epacadostat inhibits IDO1 by competitively blocking it, without interfering with IDO2 or tryptophan 2,3-dioxygenase (TDO). It has antitumor activity in some models, though is most effective when combined with other immunotherapy agents.
Brilanestrant (INN) is a nonsteroidal combined selective estrogen receptor modulator (SERM) and selective estrogen receptor degrader (SERD) that was discovered by Aragon Pharmaceuticals and was under development by Genentech for the treatment of locally advanced or metastatic estrogen receptor (ER)-positive breast cancer.
ERX-11, also known as ERα coregulator-binding modulator-11, is a novel antiestrogen and experimental hormonal antineoplastic agent which is being researched for the potential treatment of estrogen receptor-positive breast cancer. It is not a competitive antagonist of the estrogen receptor (ER) like conventional antiestrogens such as tamoxifen or fulvestrant; instead of binding to the ligand-binding site of the ER, ERX-11 interacts with a different part of the ERα and blocks protein–protein interactions of the ERα with coregulators that are necessary for the receptor to act and regulate gene expression. It was designed to bind to the coregulator binding region of the ERα and inhibit the ERα/coactivator interaction, although its precise binding site and mode of action have yet to be fully elucidated and understood. Nonetheless, it is clear that ERX-11 binds within the AF-2 domain of the ERα.
