Carbonic anhydrase II, is one of sixteen forms of human α carbonic anhydrases. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule. Loss of carbonic anhydrase activity in bones impairs the ability of osteoclasts to promote bone resorption, leading to osteopetrosis.
Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.
Probable G-protein coupled receptor 63 is a protein that in humans is encoded by the GPR63 gene.
Integral membrane protein GPR155, also known as G protein-coupled receptor 155, is a protein that in humans is encoded by the GPR155 gene. Mutations in this gene may be associated with autism.
Carbonic anhydrase IX is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma (RCC) as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis.
Melanocyte protein PMEL also known as premelanosome protein (PMEL) or silver locus protein homolog (SILV) is a protein that in humans is encoded by the PMEL gene. Its gene product may be referred to as PMEL, silver, ME20, gp100 or Pmel17.
Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene.
Carbonic anhydrase 6 is an enzyme that in humans is encoded by the CA6 gene. It is also called 'gustin' because of its presence in saliva, and lower-than-normal levels of salivary zinc in individuals with hypogeusia.
Ras-related protein Rab-17 is a protein that in humans is encoded by the RAB17 gene.
Hermansky–Pudlak syndrome 4 protein is a protein that in humans is encoded by the HPS4 gene.
Neuronal membrane glycoprotein M6-b is a protein that in humans is encoded by the GPM6B gene.
Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.
Cysteine-rich with EGF-like domain protein 1 is a protein that in humans is encoded by the CRELD1 gene.
Ubiquitin-like protein 3 is a protein that in humans is encoded by the UBL3 gene.
Carbonic anhydrase 5B, mitochondrial is an enzyme that in humans is encoded by the CA5B gene.
Transmembrane protein 150A is a protein that, in humans, is encoded by the TMEM150A gene.
Carbonic anhydrase-related protein 11 is a protein that in humans is encoded by the CA11 gene.
Keratinocyte differentiation-associated protein is a protein that in humans is encoded by the KRTDAP gene.
Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene.
Carbonic anhydrase 13 is a protein that in humans is encoded by the CA13 gene.
