Clostridium autoethanogenum

Last updated

Clostridium autoethanogenum
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Kingdom: Bacillati
Phylum: Bacillota
Class: Clostridia
Order: Eubacteriales
Family: Clostridiaceae
Genus: Clostridium
Species:
C. autoethanogenum
Binomial name
Clostridium autoethanogenum
Abrini et al. 1994

Clostridium autoethanogenum is an anaerobic bacterium that produces ethanol from carbon monoxide, in so-called syngas fermentation, being one of the few known microorganisms to do so. It is gram-positive, spore-forming, rod-like, motile, and was first isolated from rabbit feces. Its type strain is strain JA1-1. [1] Its genome has been sequenced, [2] and the genes required for utilizing carbon monoxide as a sole carbon and energy source have been determined. [3]

Contents

As a chemoautotrophic gas-fermenting organism, it possesses the Wood-Ljungdahl carbon fixation pathway, which allows the conversion of C1-gases into the biomass precursor acetyl-CoA and other specific products, while generating ATP for growth. [4]

Uses

This species is the key to the technology developed by Lanzatech to produce ethanol on a commercial scale from waste carbon monoxide gas of factory emissions. [5] On a laboratory scale, reports include production of butanol, 3-hydroxybutyrate, ethylene glycol and other compounds. [4]

References

  1. ↑ Abrini, Jamal; Naveau, Henry; Nyns, Edmond-Jacques (1994). "Clostridium autoethanogenum, sp. nov., an anaerobic bacterium that produces ethanol from carbon monoxide". Archives of Microbiology. 161 (4): 345–351. Bibcode:1994ArMic.161..345A. doi:10.1007/BF00303591. ISSN   0302-8933. S2CID   206774310.
  2. ↑ Bruno-Barcena, J. M.; Chinn, M. S.; Grunden, A. M. (2013). "Genome Sequence of the Autotrophic Acetogen Clostridium autoethanogenum JA1-1 Strain DSM 10061, a Producer of Ethanol from Carbon Monoxide". Genome Announcements. 1 (4): e00628-13–e00628-13. doi:10.1128/genomeA.00628-13. ISSN   2169-8287. PMC   3744686 . PMID   23950130.
  3. ↑ Woods, Craig; Humphreys, Christopher M.; Tomi-Andrino, Claudio; Henstra, Anne M.; Köpke, Michael; Simpson, Sean D.; Winzer, Klaus; Minton, Nigel P. (2022-04-12). Nojiri, Hideaki (ed.). "Required Gene Set for Autotrophic Growth of Clostridium autoethanogenum". Applied and Environmental Microbiology. 88 (7): e02479–21. Bibcode:2022ApEnM..88E2479W. doi:10.1128/aem.02479-21. ISSN   0099-2240. PMC   9004356 . PMID   35285680.
  4. 1 2 Wan, Sai; Lai, Mingchi; Gao, Xinyu; Zhou, Mingxin; Yang, Song; Li, Qiang; Li, Fuli; Xia, Lin; Tan, Yang (2024-03-01). "Recent progress in engineering Clostridium autoethanogenum to synthesize the biochemicals and biocommodities". Synthetic and Systems Biotechnology. 9 (1): 19–25. doi:10.1016/j.synbio.2023.12.001. ISSN   2405-805X. PMC   10776380 . PMID   38205027.
  5. ↑ Heffernan, James K.; Valgepea, Kaspar; de Souza Pinto Lemgruber, Renato; Casini, Isabella; Plan, Manuel; Tappel, Ryan; Simpson, Sean D.; Köpke, Michael; Nielsen, Lars K.; Marcellin, Esteban (2020-03-27). "Enhancing CO2-Valorization Using Clostridium autoethanogenum for Sustainable Fuel and Chemicals Production". Frontiers in Bioengineering and Biotechnology. 8 204. doi: 10.3389/fbioe.2020.00204 . ISSN   2296-4185. PMC   7135887 . PMID   32292775.


Further reading


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.