Compression stockings (Flight Socks, Support Bandage) are a specialized hosiery designed to help prevent the occurrence of, and guard against further progression of, venous disorders [1] such as edema, phlebitis and thrombosis. Compression stockings are elastic compression garments worn around the leg, compressing the limb. This reduces the diameter of distended veins and increases venous blood flow velocity and valve effectiveness. Compression therapy helps decrease venous pressure, prevents venous stasis and impairments of venous walls, and relieves heavy and aching legs.
Knee-high compression stockings are used not only to help increase circulation, but also to help prevent the formation of blood clots in the lower legs. They also aid in the treatment of ulcers of the lower legs.
Unlike traditional dress or athletic stockings and socks, compression stockings use stronger elastics to create significant pressure on the legs, ankles and feet. Compression stockings are tightest at the ankles and gradually become less constrictive toward the knees and thighs. By compressing the surface veins, arteries and muscles, they force circulating blood through narrower channels. As a result, the arterial pressure is increased, which causes more blood to return to the heart and less blood to pool in the feet.
There are two types of compression stockings, gradient and anti-embolism. [2]
Treatment is usually prescribed by a physician to relieve all manifestations of chronic venous disease and prevent venous troubles. The use of elastic compression stockings can reduce volumetric variations during standing hours. Compression stockings are recommended under the following conditions:
Edema is a condition where the opposing forces that occur in the small blood vessels and capillaries cause a net ultrafiltration of plasma water into the soft tissues.
Chronic peripheral venous insufficiency is when the veins cannot pump deoxygenated blood back to the heart.
Varicose veins are saccular and distended veins which can expand considerably and may cause painful venous inflammation. Once developed, they will not disappear on their own. The formation of varicose veins is an externally visible sign of venous weakness.
Many physicians and vein specialists recommend wearing compression stockings after varicose vein stripping, but studies show that wearing an elastic compression stocking has no additional benefit after the application of elastic bandaging for three days in post-operative care following the stripping of the great saphenous vein as assessed by control of limb, edema, pain, complications and return to work. [3]
Deep vein thrombosis occurs when blood flow decreases (especially in the lower extremities), causing blood to pool in the legs and leading to blood clot (thrombus) formation. Evidence does not suggest a benefit in post thrombotic syndrome rates following DVT. [4] Compression stockings are beneficial in reducing symptomless deep vein thrombosis among airline passengers flying for 7 hours or more. [5]
Pharmacological (warfarin, unfractionated heparin, low molecular weight heparin) and mechanical measures (graded compression stockings, intermittent pneumatic compression devices, and venous foot pumps) are used to prevent venous thromboembolism (VTE) in clinical practice. For cases in which the bleeding risk is high and pharmacologic measures are contraindicated, the use of mechanical prophylaxis is recommended. [6] Graduated compression stockings can effectively prevent VTE in hospitalized patients by applying different pressure to the leg. The meta-analysis of general surgical patients revealed that graduated compression stockings decreased their risk of developing VTE by 68% compared to placebo. [7]
Twenty randomized controlled trials analyzed the effectiveness of graduated compression stockings alone or with other additional prophylaxis in prevention of deep vein thrombosis. These trials included 1,681 patients after general surgery, orthopedic surgery, and medical patients. They concluded that graduated compression stockings are effective in deep vein thrombosis prophylaxis in patients who have undergone general and orthopedic surgery. [8]
Combining graduated compression stockings with other mechanical and pharmacological measures can increase the effectiveness of VTE prophylaxis by 60%. [9] However, another study performed in France involved 407 ICU patients and showed no difference in the effectiveness of the VTE prevention for patients who used compression stockings alone or in combination with intermittent pneumatic devices. [10]
Lymphedema occurs when a body part swells due to an abnormal accumulation of lymph fluid, occurring when there is interference with the normal drainage of lymph fluid back into the blood, commonly swelling the arm, leg, neck or abdomen.
Phlebitis is the term used when inflammation and clotting occurs in a vein, most often a leg vein, due to infection, inflammation, or trauma. People with varicose veins are more often affected. Inflammation occurs suddenly, causing the thrombus to adhere firmly to the vein wall and risking clogging a superficial vein.
Lipodermatosclerosis is the term used to refer to the inflammation of subcutaneous fat, a form of panniculitis.
Hormones released during pregnancy and the expanding uterus (pressure on the inferior vena cava – the major vein returning blood up to the heart) can affect leg veins. [11]
The use of lower leg compression stockings has been found to reduce symptoms and heart rate when standing upright, in patients with postural orthostatic tachycardia syndrome. Usage of compression garments on abdomen and thighs, and a combination of abdominal/thigh and leg covering compression was found to be more effective, with the latter having the most beneficial outcome. [12]
Caution should be used in those with advanced peripheral obstructive arterial disease, heart failure, septic phlebitis, oozing dermatitis and advanced peripheral neuropathy in regard to wearing compression stockings. [13]
First the proper size stocking is determined by measuring the legs. Aseptic technique (antiseptic wound cleaning) is not necessary unless the skin is broken. The person is placed in the supine position (laying down) in bed for fifteen minutes prior to measuring for fit. This allows for venous return and stability before measuring. [14] : 745
Stockings are best applied upon waking before the person has gotten out of bed, has been sitting or standing and before venous stasis or edema has had a chance to develop. [14] : 745 The use of stockings for the entire day is more effective than just half the day or not using compression stockings at all. [15]
Fit is critical to the therapeutic effect of compression stockings. A study listed in the American Journal of Nursing in August 2008 showed that compression stockings were incorrectly sized in just under 30% of the cases studied. It found that additional education was needed not only for patients, but also for medical staff. [16]
These stockings are designed to remedy impaired "musculovenous pump" performance caused by incompetent leg vein valves. They are woven in such a way that the compression level is highest around the ankle and lessens towards the top of the hose.
Doctors will typically recommend these stockings for those who are prone to blood clots, lower limb edema, and blood pooling in the legs and feet from prolonged periods of sitting or inactivity. They are also frequently used to address complications caused by diabetes, lymphedema, thrombosis, cellulitis, and other conditions. [17]
They are worn by those who are ambulatory in most cases, helping calf muscles to perform their pumping action more efficiently to return blood to the heart. In some cases, they are worn by those at increased risk of circulatory problems, such as diabetics, whose legs are prone to excessive swelling. A common indicator for the prescription of such stockings is chronic peripheral venous insufficiency, caused by incompetent perforator veins. Low-pressure compression stockings are available without prescription in most countries, and may be purchased at a pharmacy or medical supply store. Stockings with a higher pressure gradient, say, above 25–30 mmHg, may require a prescription from a doctor.[ citation needed ]
There are several crucial cautionary steps that need to be taken before using compression stockings:
Vascular doctors and nurses may use special pads to ensure uniform higher pressure around the circumference of the ankle (to smooth out the irregular cross-sectional profile.) Self-prescription is reasonably safe assuming that the compression gradient is 15–20 mmHg, the ABPI (for both legs) is >1.0 and that the stockings fit correctly. "Firm" gradient stockings (20–30 mmHg and 30–40 mmHg) should generally be worn only on medical advice.
Current research reports mixed results of compression socks on athletic performance. [18] [19]
The graduated (gradient, graded) compression stockings and anti-embolism compression stockings come in knee-high and thigh-high length. [20] A meta-analysis by Sajid et al. was done to compare knee-high and thigh-high graded compression stockings in regards of deep vein thrombosis prevention in medical and surgical patients. [21] The analysis determined that there was a 6% risk of developing deep vein thrombosis when wearing knee-high stockings and 4% when wearing thigh-high stockings, but also found significant heterogeneity, and thus it concluded that there is not enough evidence that one length is superior to the other, and suggests that knee-high compression stockings should be the first choice for the deep vein thrombosis prevention in medical and surgical patients.
Knee-high stockings are more comfortable, easier to apply, and wearing them increases patients' compliance with treatment. [22] Knee-high stockings are easier to size for limb measurement than thigh-high compression stockings. [9] Thigh-high compression stockings may create a tourniquet effect and cause localized restriction when rolled down. [23] A study of patients treated for post-thrombotic syndrome, performed in Italy, revealed that redness and itching of the skin was reported in 41% of patients wearing thigh-high and 27% in patients wearing knee-high compression stockings. Consequently, 22% of thigh-high wearers and 14% of knee-high wearers stopped the treatment. [24]
Compression stockings are constructed using elastic fibers or rubber. These fibers help compress the limb, aiding in circulation.
Compression stockings are offered in different levels of compression. The unit of measure used to classify the pressure of the stockings is mmHg. They are often sold in a variety of pressure ranges.[ citation needed ]
Use of compression therapy is not new. As early as the Neolithic period (5000-2500 BCE), images of soldiers with bandaged lower extremities were found in the drawings of the caves of Tassili in Sahara. The Edwin Smith Papyrus, which dates to roughly 1600 BCE, included additional evidence of mechanical compression therapy for legs. [6] Hippocrates treated his patients' leg ulcers with tight bandages, which were described in his Corpus Hippocraticum (450–350 BCE). [25] Galen (130-200 CE) used wool and linen compression bandages to prevent blood from pooling in the legs, and Oribassius (324 CE) would use tight bandages to treat leg ulcers. [6]
During the Middle Ages, the leading use of leg compression bandages was mainly for therapy. This is evidenced by the works of Avicenna (980–1037); Giovanni Michele Savonarola (1384–1468); Ambroise Paré (1510–1590); Girolamo Fabrizio di Acquapendente (1537–1619); and other scientists. [6] Guy de Chauliac in his book Chirurgica Magna described the use of compression bandages to treat enlarged veins of the legs. [25] Giovanni Michele Savonarola also treated varicose veins with the help of the leg bandages and described their proper application in his work Practice.
In 1628, William Harvey discovered the link between venous stasis and the external pressure. Following that discovery, various compression measures were introduced for therapy: laced stockings, elastic bands, and tight bandages with resin. Later, new textile materials started to be used for the production of compression stockings: natural or cellulose fibers (silk, cotton, coconut) and chemical (acrylic, nylon, polyester). [6] It was only at the end of the 19th century, after Fisher and Lasker[ citation needed ], German phlebologists, discovered that the application of the external pressure helped to treat blood clots in the lower extremities, that compression stockings started to be used for the treatment of deep vein thrombosis. [25]
These stockings are commonly referred to as TED hose, short for thromboembolism-deterrent hose. They are used to support the venous and lymphatic drainage of the leg. [26]
There is a possible link between a common physical defect in the heart and potentially deadly stroke that could occur during long aeroplane flights. [27] The connection, called "economy class stroke syndrome," has been reported in healthy, young travelers who had ischemic strokes during or shortly after long air trips. Prolonged sitting associated with air travel is known to be a cause of clots in the legs. Upward of 30 percent of the population is estimated to have patent foramen ovale (PFO), a common condition where a small hole exists between the right and left sides of the heart. PFO rarely causes any adverse medical condition and can be determined only through specific diagnostic tests such as an echocardiogram.
Varicose veins, also known as varicoses, are a medical condition in which superficial veins become enlarged and twisted. Although usually just a cosmetic ailment, in some cases they cause fatigue, pain, itching, and nighttime leg cramps. These veins typically develop in the legs, just under the skin. Their complications can include bleeding, skin ulcers, and superficial thrombophlebitis. Varices in the scrotum are known as varicocele, while those around the anus are known as hemorrhoids. The physical, social, and psychological effects of varicose veins can lower their bearers' quality of life.
Veins are blood vessels in the circulatory system of humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are those of the pulmonary and fetal circulations which carry oxygenated blood to the heart. In the systemic circulation, arteries carry oxygenated blood away from the heart, and veins return deoxygenated blood to the heart, in the deep veins.
Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus.
Venous thrombosis is the blockage of a vein caused by a thrombus. A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off (embolizes) and flows to the lungs to lodge there, it becomes a pulmonary embolism (PE), a blood clot in the lungs. The conditions of DVT only, DVT with PE, and PE only, are all captured by the term venous thromboembolism (VTE).
Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly in the legs or pelvis. A minority of DVTs occur in the arms. Symptoms can include pain, swelling, redness, and enlarged veins in the affected area, but some DVTs have no symptoms.
Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. They are used in the prevention of blood clots and, in the treatment of venous thromboembolism, and the treatment of myocardial infarction.
Thromboembolism is a condition in which a blood clot (thrombus) breaks off from its original site and travels through the bloodstream to obstruct a blood vessel, causing tissue ischemia and organ damage. Thromboembolism can affect both the venous and arterial systems, with different clinical manifestations and management strategies.
Endovenous laser treatment (ELT) is a minimally invasive ultrasound-guided technique used for treating varicose veins using laser energy commonly performed by a phlebologist, interventional radiologist or vascular surgeon.
Venous ulcer is defined by the American Venous Forum as "a full-thickness defect of skin, most frequently in the ankle region, that fails to heal spontaneously and is sustained by chronic venous disease, based on venous duplex ultrasound testing." Venous ulcers are wounds that are thought to occur due to improper functioning of venous valves, usually of the legs. They are an important cause of chronic wounds, affecting 1% of the population. Venous ulcers develop mostly along the medial distal leg, and can be painful with negative effects on quality of life.
Renal vein thrombosis (RVT) is the formation of a clot in the vein that drains blood from the kidneys, ultimately leading to a reduction in the drainage of one or both kidneys and the possible migration of the clot to other parts of the body. First described by German pathologist Friedrich Daniel von Recklinghausen in 1861, RVT most commonly affects two subpopulations: newly born infants with blood clotting abnormalities or dehydration and adults with nephrotic syndrome.
Dalteparin is a low molecular weight heparin. It is marketed as Fragmin. Like other low molecular weight heparins, dalteparin is used for prophylaxis or treatment of deep vein thrombosis and pulmonary embolism to reduce the risk of a stroke or heart attack. Dalteparin acts by potentiating the activity of antithrombin III, inhibiting formation of both Factor Xa and thrombin. It is normally administered by self-injection.
Vascular disease is a class of diseases of the vessels of the circulatory system in the body, including blood vessels – the arteries and veins, and the lymphatic vessels. Vascular disease is a subgroup of cardiovascular disease. Disorders in this vast network of blood and lymph vessels can cause a range of health problems that can sometimes become severe, and fatal. Coronary heart disease for example, is the leading cause of death for men and women in the United States.
Post-thrombotic syndrome (PTS), also called postphlebitic syndrome and venous stress disorder is a medical condition that may occur as a long-term complication of deep vein thrombosis (DVT).
Vein stripping is a surgical procedure done under general or local anaesthetic to aid in the treatment of varicose veins and other manifestations of chronic venous disease. The vein "stripped" is usually the great saphenous vein. The surgery involves making incisions, followed by insertion of a special metal or plastic wire into the vein. The vein is attached to the wire and then pulled out from the body. The incisions are stitched up and pressure dressings are often applied to the area.
Chronic venous insufficiency (CVI) is a medical condition in which blood pools in the veins, straining the walls of the vein. The most common cause of CVI is superficial venous reflux which is a treatable condition. As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs. If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis.
Venous stasis, or venostasis, is a condition of slow blood flow in the veins, usually of the legs.
Intermittent pneumatic compression is a therapeutic technique used in medical devices that include an air pump and inflatable auxiliary sleeves, gloves or boots in a system designed to improve venous circulation in the limbs of patients who have edema or the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), or the combination of DVT and PE which is venous thrombeombolism (VTE).
Prothrombin G20210A is a genotypic trait that provides a prompter coagulation response. It increases the risk of blood clots including from deep vein thrombosis, and of pulmonary embolism. One copy of the mutation increases the risk of a blood clot from 1 in 1,000 per year to 2.5 in 1,000. Two copies increases the risk to up to 20 in 1,000 per year. Most people never develop a blood clot in their lifetimes.
Superficial vein thrombosis (SVT) is a blood clot formed in a superficial vein, a vein near the surface of the body. Usually there is thrombophlebitis, which is an inflammatory reaction around a thrombosed vein, presenting as a painful induration with redness. SVT itself has limited significance when compared to a deep vein thrombosis (DVT), which occurs deeper in the body at the deep venous system level. However, SVT can lead to serious complications, and is therefore no longer regarded as a benign condition. If the blood clot is too near the saphenofemoral junction there is a higher risk of pulmonary embolism, a potentially life-threatening complication.
Thrombosis prevention or thromboprophylaxis is medical treatment to prevent the development of thrombosis in those considered at risk for developing thrombosis. Some people are at a higher risk for the formation of blood clots than others, such as those with cancer undergoing a surgical procedure. Prevention measures or interventions are usually begun after surgery as the associated immobility will increase a person's risk.
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: CS1 maint: multiple names: authors list (link)The use of elastic compression stockings can reduce volumetric variations during working hours, with the use of stockings for the entire day being better than for just half the day.
Graduated compression stockings were used incorrectly in 29 percent of the patients and sized incorrectly in 26 percent of the patients according to new research. These stockings play an important role in preventing the formation of deep vein clots that can result in pulmonary complications and death.