Route 66 is an east-west state highway running from Meriden to Windham, serving as an alternate east–west route to US 6 through east-central Connecticut.
Route 83 is a 35.65-mile-long (57.37 km) north–south state highway in the Greater Hartford and Greater Springfield areas of the U.S. states of Connecticut and Massachusetts. It serves as the main north–south artery for the towns of Manchester, Vernon, Ellington, and Somers, and continues through East Longmeadow center into downtown Springfield. The route in Massachusetts is town-maintained, except for the ramps connecting to U.S. Route 5 parallel to Interstate 91.
Route 161 is a state highway in southeastern Connecticut, running from the shoreline village of Niantic in East Lyme to the village of Chesterfield in Montville.
Route 37 is a north–south state highway in Connecticut running for 18.66 miles (30.03 km) from I-84, Route 39 and Route 53 in Danbury, through New Fairfield, to U.S. Route 7 in New Milford. The northernmost section between the town centers of Sherman and New Milford was once part of an early toll road known as the New Milford and Sherman Turnpike chartered in 1818.
Route 43 is a Connecticut state highway. It is 5.06 miles (8.14 km) long and runs north–south within the town of Cornwall. It connects the town center with the village of Cornwall Hollow near the Canaan town line.
Route 45 is a Connecticut state highway from US 202 in Washington to US 7 in Cornwall, in the rural northwest of the state. It is 10.29 miles (16.56 km) long and runs north–south.
Route 81 is a state highway in Connecticut from Clinton center through Killingworth center to the village of Higganum in the town of Haddam.
Route 154 is a state highway in Connecticut running for 28.24 miles (45.45 km). It serves as one of the main thoroughfares in the town of Old Saybrook, intersecting twice with U.S. Route 1. North of Interstate 95 (I-95), Route 154 runs parallel to Route 9, along to the west bank of the Connecticut River. The route ends in Higganum at Route 9.
Route 82 is an east–west state highway in Connecticut running for 28.47 miles (45.82 km) from Route 9 in Chester to Route 2/Route 32 in Norwich.
Route 151 is a Connecticut state highway in the Connecticut River valley running from East Haddam via Moodus to the village of Cobalt in East Hampton.
Route 193 is a 9.40-mile-long (15.13 km) state highway in the U.S. states of Connecticut and Massachusetts. The route travels between the town centers of Thompson, Connecticut and Webster, Massachusetts. The road closely parallels Interstate 395 throughout its entire length. It is signed North-South, with the exception of one East-West Sign at the South end.
Route 199 is a rural state highway in western Connecticut, running from Roxbury to Washington.
Route 149 is a state highway in east-central Connecticut running from Route 82 in East Haddam center north to Route 2 in Colchester.
Route 148 is a state highway in southern and southeastern Connecticut running from Route 79 in Killingworth to Route 82 in the village of Hadlyme. Route 148 crosses the Connecticut River using the Chester–Hadlyme Ferry.
Route 132 is a state highway in western Connecticut, running from Route 47 in Woodbury, through Bethlehem center, to Route 63 in Watertown.
Route 112 is a state highway in northwestern Connecticut, running entirely within the town of Salisbury. The route serves the village of Lime Rock.
Route 133 is a state highway in western Connecticut, running from U.S. Route 202 in Brookfield to Route 67 in Bridgewater.
Route 156 is a Connecticut state highway running from East Haddam to Waterford.
Route 197 is a 14.17-mile-long (22.80 km) state highway in northeastern Connecticut and southern Massachusetts, running from Union, Connecticut, to Dudley, Massachusetts. The Connecticut section is signed as an east–west route, while the Massachusetts section is signed north–south.
U.S. Route 44 (US 44) is an east–west United States Numbered Highway that runs for 237 miles (381 km) through four states in the Northeastern United States. The western terminus is at US 209 and New York State Route 55 (NY 55) in Kerhonkson, New York, a hamlet in the Hudson Valley region. The eastern terminus is at Route 3A in Plymouth, Massachusetts.
Route 151 in Haddam 
Route 66 in East Hampton 
