Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DNA was performed in 1980, by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989. The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990. It is thought to be able to cure many genetic disorders or treat them over time.
Cell therapy is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or grafting stem cells to regenerate diseased tissues.
The Archives of Sexual Behavior is a peer-reviewed academic journal in sexology. It is the official publication of the International Academy of Sex Research.
Xenobiotica is a peer-reviewed medical journal that publishes comprehensive research papers on all areas of xenobiotics. It is published by Informa plc and covers six main areas:
Advances in Therapy is a monthly peer-reviewed medical journal covering clinical medicine, especially research on pharmaceuticals. The Managing Editor is Clare Shepherd. The journal publishes original clinical research papers and review articles. The journal was established in 1984 and published by Health Communications. Since 2008 it has been published by Springer Science+Business Media.
Clinical Colorectal Cancer is a peer-reviewed medical journal published by CIG Media Group from 2001 to 2010 and by Elsevier since 2011. It publishes original articles describing various aspects of clinical and translational research of gastrointestinal cancers. The journal is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. The main emphasis is on recent scientific developments in all areas related to gastrointestinal cancers. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.
Clinical Lung Cancer is a peer-reviewed medical journal that has been published by Elsevier since 2011. It was established by the CIG Media Group in 1999.
The Journal of Receptors and Signal Transduction is a peer-reviewed scientific journal that publishes laboratory and clinical studies, reviews, and brief communications on biological receptors and associated signal transduction pathways for ligands involved in the regulation of central and peripheral tissues and cells. It is published by Informa. The editors in chief are Alex N. Eberle and Terrence Kenakin.
Pharmaceutical Research is an official journal of the American Association of Pharmaceutical Scientists and covers research spanning the entire spectrum of drug discovery, development, evaluation, and regulatory approval. Small drug molecules, biotechnology products including genes, peptides, proteins and vaccines, and genetically engineered cells are an integral part of papers published. Current emphasis of the journal includes the following areas: preformulation; drug delivery and targeting; formulation design, engineering, and processing; pharmacokinetics, pharmacodynamics, and pharmacogenomics; molecular biopharmaceutics and drug disposition; and computational biopharmaceutics, among others.
Clinical Cancer Research is a peer-reviewed medical journal on oncology, including the cellular and molecular characterization, prevention, diagnosis, and therapy of human cancer, medical and hematological oncology, radiation therapy, pediatric oncology, pathology, surgical oncology, and clinical genetics. The applications of the disciplines of pharmacology, immunology, cell biology, and molecular genetics to intervention in human cancer are also included. One of the main interests of Clinical Cancer Research is on clinical trials that evaluate new treatments together with research on pharmacology and molecular alterations or biomarkers that predict response or resistance to treatment. Another priority for Clinical Cancer Research is laboratory and animal studies of new drugs as well as molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype, and metastatic disease. The journal is published by the American Association for Cancer Research.
Mechanisms of Development is a peer-reviewed scientific journal covering all aspects of developmental biology. It is the official journal of the International Society of Developmental Biologists and is published by Elsevier. The journal was established in 1972 as Cell Differentiation and was renamed Cell Differentiation and Development in 1988. It acquired its current name in December 1990. The editor-in-chief is D. Wilkinson. A separate section of the journal, Gene Expression Patterns, covers research on cloning and gene expression. In 2020 the journal became Cells & Development with the subtitle: 'Cell and Developmental Biology and their Quantitative Approaches'.
Hypertension is a monthly peer-reviewed scientific journal that was established in 1979. It is published on behalf of the American Heart Association by Lippincott Williams & Wilkins. The editor-in-chief is Rhian M. Touyz. The journal publishes original manuscripts, invited review summaries, invited case-based reviews, recent study highlights, invited brief commentaries, scientific or technical tutorials, letters to the editor, and novel findings of unusual interest. It covers all aspects of research on hypertension, including pathophysiology, blood pressure regulation, clinical treatment, and prevention.
Current Gene Therapy is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Liang Cheng. The focus of this journal is pre-clinical or clinical research on gene therapy. Formats of publication include original research reports, review papers, and rapid communications ("letters").
Clinical Case Studies is a bimonthly peer-reviewed medical journal that covers the field of psychotherapy, including individual, couples, and family therapy. The editor-in-chief is Daniel L. Segal. It was established in 2002 and is published by SAGE Publications.
Drugs & Aging is a monthly peer-reviewed medical journal published by Springer Nature under their Adis International imprint. It contains primarily review articles covering optimum use of drug therapies in older adults.
Expert Review of Hematology is a MEDLINE-indexed, peer-reviewed, international medical journal publishing review articles and original papers on all aspects of hematology. It is part of the Expert Review series, published by Informa.
The Canadian Journal of Occupational Therapy is a peer-reviewed academic journal that covers the field of occupational therapy. The editor-in-chief is Catherine Vallée. It was established in 1933 and is published by SAGE Publications.
Alternative Therapies in Health and Medicine is a bimonthly peer-reviewed medical journal covering alternative medical treatments. It publishes case reports, original research papers, and systematic reviews. It was established in 1995 by founding editor Larry Dossey and is published bimonthly by InnoVision Health Media. The current editor-in-chief is Andrew W. Campbell.
Clinical Laboratory is a monthly peer-reviewed medical journal covering all aspects of laboratory medicine and transfusion medicine as well as tissue transplantation and hematopoietic, cellular, and gene therapies. It was established in 1955 as Das ärztliche Laboratorium: Zeitschrift für den Laboratoriumsarzt und die ärztliche Praxis. The title was changed to Klinisches Labor in 1991 with the English subtitle Clinical Laboratory. The English title became the sole title from 1997. The editor-in-chief is Michael F. Holick.
The Journal of Extracellular Vesicles is a peer-reviewed open-access scientific journal covering research on lipid bilayer-delimited particles known as extracellular vesicles (EVs). EVs are released from cells and include endosome-origin exosomes and plasma membrane-derived ectosomes/microvesicles. The journal is helmed by editor-in-chief Jan Lötvall and is published by Wiley on behalf of the International Society for Extracellular Vesicles (ISEV). It was established in 2012. Until August 2019, the editors-in-chief were Clotilde Théry, Yong Song Gho, and Peter Quesenberry. They were succeeded by Jan Lötvall.
