DHRSX

DHRSX
Identifiers
Aliases	DHRSX , CXorf11, DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6, dehydrogenase/reductase (SDR family) X-linked, dehydrogenase/reductase X-linked
External IDs	MGI: 2181510 HomoloGene: 78041 GeneCards: DHRSX
Gene location (Human) Chr. X chromosome (human) [1] Band Xp22.33 and Yp11.2 Start 2,219,506 bp [1] End 2,502,805 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium ganglionic eminence body of pancreas right atrium right lobe of liver gastrocnemius muscle left ventricle monocyte body of stomach right adrenal gland n/a More reference expression data BioGPS n/a
Gene ontology Molecular function oxidoreductase activity Cellular component extracellular region Biological process positive regulation of autophagy Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 207063 236082 Ensembl ENSG00000169084 ENSMUSG00000063897 UniProt Q8N5I4 Q8VBZ0 RefSeq (mRNA) NM_145177 NM_001033326 RefSeq (protein) NP_660160 n/a Location (UCSC) Chr X: 2.22 – 2.5 Mb n/a PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Dehydrogenase/reductase (SDR family) X-linked also known as DHRSX is an enzyme which in humans is encoded by the pseudoautosomal DHRSX gene. ^[4] DHRSX is a member of the short-chain dehydrogenase family of oxidoreductase enzymes. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000169084 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Gianfrancesco F, Sanges R, Esposito T, Tempesta S, Rao E, Rappold G, Archidiacono N, Graves JA, Forabosco A, D'Urso M (December 2001). "Differential Divergence of Three Human Pseudoautosomal Genes and Their Mouse Homologs: Implications for Sex Chromosome Evolution". Genome Res. 11 (12): 2095–100. doi:10.1101/gr.197001. PMC   311231 . PMID   11731500.
5. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (November 2008). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem. Biol. Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC   2896744 . PMID   19027726.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Oh JH, Yang JO, Hahn Y, et al. (2005). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID   16341674. S2CID   69278.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell. Proteomics. 7 (3): 499–508. doi: 10.1074/mcp.M700325-MCP200 . PMID   18029348.