GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked via G-proteins to potassium channels. The changing potassium concentrations hyperpolarize the cell at the end of an action potential. The reversal potential of the GABAB-mediated IPSP is −100 mV, which is much more hyperpolarized than the GABAA IPSP. GABAB receptors are found in the central nervous system and the autonomic division of the peripheral nervous system.
Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods including kale, beans, tea, spinach, and broccoli. Kaempferol is a yellow crystalline solid with a melting point of 276–278 °C (529–532 °F). It is slightly soluble in water and highly soluble in hot ethanol, ethers, and DMSO. Kaempferol is named for 17th-century German naturalist Engelbert Kaempfer.
Salvia miltiorrhiza, also known as red sage, redroot sage, Chinese sage, or danshen, is a perennial plant in the genus Salvia, highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at 90 to 1,200 m elevation, preferring grassy places in forests, hillsides, and along stream banks. The specific epithet miltiorrhiza means "red ochre root".
Shō-saiko-tō (小柴胡湯), also known as minor bupuleurum formula and xiǎocháihútāng (XCHT), is a herbal supplement, believed to enhance liver health. Sho-Saiko-To is a widely used prescription drug in China and is a listed formula in China and Japan as a Kampo medicine. There are currently ongoing clinical trials for Sho-Saiko-To at University of California, San Diego and Memorial Sloan-Kettering Cancer Center. The active ingredients of sho-saiko-to discovered so far include baicalin, baicalein, glycyrrhizin, saikosaponins, ginsenosides, wogonin, and gingerol.
Shennong Bencaojing is a Chinese book on agriculture and medicinal plants, traditionally attributed to Shennong. Researchers believe the text is a compilation of oral traditions, written between the first and second centuries AD. The original text no longer exists, but is said to have been composed of three volumes containing 365 entries on medicaments and their description.
Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea. It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant. Salidroside may be more active than rosavin, even though many commercially marketed Rhodiola rosea extracts are standardized for rosavin content rather than salidroside.
Royal Tramp is a 2008 Chinese television series adapted from Louis Cha's novel The Deer and the Cauldron. Produced by Zhang Jizhong and Huayi Brothers, the series consists of 50 episodes, filmed in high definition. The series was first broadcast on Jiangsu TV in China in 2008 and was subsequently aired on TVB in Hong Kong and other countries.
Therapeutic Target Database (TTD) is a pharmaceutical and medical repository constructed by the Innovative Drug Research and Bioinformatics Group (IDRB) at Zhejiang University, China and the Bioinformatics and Drug Design Group at the National University of Singapore. It provides information about known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Detailed knowledge about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, and clinical development status. TTD is freely accessible without any login requirement at https://idrblab.org/ttd/.
Huáng bǎi, huáng bó or huáng bò is one of the fifty fundamental herbs of traditional Chinese medicine. Known also as Cortex Phellodendri, it is the bark of one of two species of Phellodendron tree: Phellodendron amurense or Phellodendron chinense.
The Water Margin is a 1998 Chinese television series adapted from Shi Nai'an's classical 14th-century novel of the same title. It was produced by CCTV with Zhang Jizhong as producer. It was first broadcast in China in January 1998. The series also featured action choreography by Yuen Woo-ping.
Palmatine is a protoberberine alkaloid found in several plants including Phellodendron amurense, Coptis Chinensis and Corydalis yanhusuo, Tinospora cordifolia, Tinospora sagittata, Phellodendron amurense, Stephania yunnanensis.
Graphene quantum dots (GQDs) are graphene nanoparticles with a size less than 100 nm. Due to their exceptional properties such as low toxicity, stable photoluminescence, chemical stability and pronounced quantum confinement effect, GQDs are considered as a novel material for biological, opto-electronics, energy and environmental applications.
The Heart of Woman, also known as Women, is a Taiwanese Hokkien television series that began airing on SET Taiwan in Taiwan on 21 November 2012, from Mondays to Fridays, and ends on 21 November 2013, lasting one year with a total of 262 episodes.
The QTY Code is a design method to transform membrane proteins that are intrinsically insoluble in water into variants with water solubility, while retaining their structure and function.
Zinc lactate is a chemical compound, a salt of zinc and lactic acid with the formula Zn(C3H5O3)2.
Isaria cicadae is an ascomycete fungus that parasitizes cicada larvae. It forms white and yellow asexual fruiting structures resembling synnema. While mostly being found throughout Asia in warm, humid regions, it has been found on various other continents. It is known in Traditional Chinese Medicine as Chan Hua and commonly called “cicada flower.” Its medicinal uses date back to the fifth century AD in China. It can also be used in various foods and tonics.
Periplocin is a plant-derived glycoside whereby the sugar moiety is linked to a steroid. It can be extracted from cortex periplocae (CPP), the dry root of Periploca sepium.
Famitinib is a tyrosine kinase receptor inhibitor developed by Jiangsu Hengrui for a variety of cancers.
Salvianolic acids are a group of polyphenolic acids consisting on several combinations of caffeic acid and danshensu through ester and enol bonds. Salvianolic acids are water-soluble components produced by many species of the genus Salvia, mainly extracted from Salvia miltiorrhiza.
