Dimple sign

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The dimple sign or Fitzpatrick's sign is a dermatological sign in which lateral pressure on the skin produces a depression. [1] [2] It is associated with dermatofibroma. [3]

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{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464206673 | IUPAC_name = (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-{(E)-2-[(1R,3R,4S)-4-chloro-3 -methoxycyclohexyl]-1-methylvinyl}-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosin-1,7,20,21(4H,23H)-tetrone | image = Pimecrolimus2DACS.svg | width = 200 | image2 = Pimecrolimus ball-and-stick.png | tradename = Elidel | Drugs.com = Monograph | pregnancy_AU = B3 | pregnancy_US = C | legal_US = Rx-only | routes_of_administration = topical | bioavailability = low systemic absorption | protein_bound = 74%–87% | metabolism = Hepatic CYP3A | elimination_half-life = | excretion = | CAS_number_Ref =   | CAS_number = 137071-32-0 | ATC_prefix = D11 | ATC_suffix = AH02 | PubChem = 16051947 | DrugBank_Ref =  

| DrugBank = DB00337
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References

  1. Aradi AJ, Wong J, Walsh M (March 1988). "The dimple sign of a ruptured lateral ligament of the ankle: brief report". J Bone Joint Surg Br. 70 (2): 327–8. doi:10.1302/0301-620X.70B2.3126191. PMID   3126191.
  2. Naversen DN, Trask DM, Watson FH, Burket JM (February 1993). "Painful tumors of the skin: "LEND AN EGG"". J. Am. Acad. Dermatol. 28 (2 Pt 2): 298–300. doi:10.1016/0190-9622(93)70039-V. PMID   8436643.
  3. Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J, Puig S (February 2006). "Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients". Br. J. Dermatol. 154 (2): 244–50. doi:10.1111/j.1365-2133.2005.06844.x. PMID   16433792. S2CID   22308659.

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