Pallor

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Pallor
Scarlet fever 1.JPG
A girl with circumoral pallor due to scarlet fever
Specialty Hematology, Rheumatology, Dermatology
Differential diagnosis Hypopigmentation

Pallor is a pale color of the skin that can be caused by illness, emotional shock or stress, stimulant use, or anemia, and is the result of a reduced amount of oxyhaemoglobin and may also be visible as pallor of the conjunctivae of the eyes on physical examination.

Contents

Pallor is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause. It is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar presentations such as hypopigmentation (lack or loss of skin pigment) or simply a lightly-melanated complexion.

In patients with dark skin, pallor is more subtle and harder to detect, often manifesting as a more grayish or ashy tone of skin in individuals with very dark brown skin, or alternatively a more yellowish tone in individuals with lighter brown skin. Assessing the palms, soles, and mucous membranes with appropriate lighting in such cases may make detection easier. [1] [2]

Causes

Effects of different skin tone on the appearance of pallor PallorSkinTones.jpg
Effects of different skin tone on the appearance of pallor
Portrait of Richard Parkes Bonington by Margaret Sarah Carpenter. Bonington was suffering from tuberculosis and the paleness of his face was noted by critics. Richard Parkes Bonington by Margaret Sarah Carpenter (nee Geddes).jpg
Portrait of Richard Parkes Bonington by Margaret Sarah Carpenter. Bonington was suffering from tuberculosis and the paleness of his face was noted by critics.

References

  1. Pusey-Reid, Eleonor; Quinn, Lisa; Samost, Mary E.; Reidy, Patricia A. (March 2023). "Skin Assessment in Patients with Dark Skin Tone". AJN, American Journal of Nursing. 123 (3): 36–43. doi:10.1097/01.NAJ.0000921800.61980.7e. ISSN   0002-936X.
  2. "Identifying AEFI in diverse skin colour". The Melbourne Vaccine Education Centre (MVEC). Murdoch Children's Research Institute . Retrieved 2025-12-09.
  3. Gupta, V. K. (19 August 2004). "Conceptual divide between adaptive and pathogenetic phenomena in migraine: nausea and vomiting" . Brain. 127 (11): E18. doi:10.1093/brain/awh279. PMID   15492109 . Retrieved 14 October 2022.
  4. Drummond, Peter D. (October 1997). "Correlates of facial flushing and pallor in anger-provoking situations". Personality and Individual Differences. 23 (4): 575–582. doi:10.1016/S0191-8869(97)00077-9.
  5. Kalantri, Ashwini; Karambelkar, Mandar; Joshi, Rajnish; Kalantri, Shriprakash; Jajoo, Ulhas (1 January 2010). "Accuracy and Reliability of Pallor for Detecting Anaemia: A Hospital-Based Diagnostic Accuracy Study". PLOS ONE. 5 (1) e8545. Bibcode:2010PLoSO...5.8545K. doi: 10.1371/journal.pone.0008545 . ISSN   1932-6203. PMC   2797134 . PMID   20049324.
  6. Mishra, Vikas A.; Harbada, Rishit; Sharma, Akhilesh (2015). "Vitamin B12 and Vitamin D Deficiencies: An Unusual Cause of Fever, Severe Hemolytic Anemia and Thrombocytopenia". Journal of Family Medicine and Primary Care. 4 (1): 145–148. doi: 10.4103/2249-4863.152276 . ISSN   2249-4863. PMC   4366991 . PMID   25811010.
  7. Fragkandrea, Ioanna; Nixon, John Alexander; Panagopoulou, Paraskevi (1 August 2013). "Signs and Symptoms of Childhood Cancer: A Guide for Early Recognition". American Family Physician. 88 (3): 185–192. PMID   23939697 . Retrieved 14 October 2022.
  8. Poterucha, Joseph T.; Bos, J. Martijn; Cannon, Bryan C.; Ackerman, Michael J. (1 August 2015). "Frequency and severity of hypoglycemia in children with beta-blocker–treated long QT syndrome". Heart Rhythm. 12 (8): 1815–1819. doi:10.1016/j.hrthm.2015.04.034. ISSN   1547-5271. PMID   25929701.
  9. Holmes, Sharon; King, Stuart; Scott, J. R. Rollin; Clemes, Stacy (2002). "Facial Skin Pallor Increases During Motion Sickness" . Journal of Psychophysiology. 16 (3): 150–157. doi:10.1027//0269-8803.16.3.150 . Retrieved 14 October 2022.