| Drosophila erecta | |
|---|---|
Scientific classification  | |
| Kingdom: | Animalia |
| Phylum: | Arthropoda |
| Class: | Insecta |
| Order: | Diptera |
| Family: | Drosophilidae |
| Genus: | Drosophila |
| Species complex: | erecta |
| Species: | D. erecta |
| Binomial name | |
| Drosophila erecta Tsacas and Lachaise, 1974 | |
Drosophila erecta is a West African species of fruit fly, and was one of 12 fruit fly genomes sequenced for a large comparative study. [1]
Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies ; tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly.
Drosophila melanogaster is a species of fly in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, D. melanogaster continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the animal.
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. For the most extensively studied species and model organism, Drosophila melanogaster, a wide range of data are presented in different formats.
Most animal testing involves invertebrates, especially Drosophila melanogaster, a fruit fly, and Caenorhabditis elegans, a nematode. These animals offer scientists many advantages over vertebrates, including their short life cycle, simple anatomy and the ease with which large numbers of individuals may be studied. Invertebrates are often cost-effective, as thousands of flies or nematodes can be housed in a single room.
The Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) was established by Richard A. Gibbs in 1996 when Baylor College of Medicine was chosen as one of six worldwide sites to complete the final phase of the international Human Genome Project. Gibbs is the current director of the BCM-HGSC.
Allan C. Spradling is an American scientist and principal investigator at the Carnegie Institution for Science and the Howard Hughes Medical Institute who studies egg development in the model organism, Drosophila melanogaster, a fruit fly. He is considered a leading researcher in the developmental genetics of the fruit fly egg and has developed a number of techniques in his career that have led to greater understanding of fruit fly genetics including contributions to sequencing its genome. He is also an adjunct professor at Johns Hopkins University and at the Johns Hopkins University School of Medicine.
A genetically modified (GM) insect is an insect that has been genetically modified, either through mutagenesis, or more precise processes of transgenesis, or cisgenesis. Motivations for using GM insects include biological research purposes and genetic pest management. Genetic pest management capitalizes on recent advances in biotechnology and the growing repertoire of sequenced genomes in order to control pest populations, including insects. Insect genomes can be found in genetic databases such as NCBI, and databases more specific to insects such as FlyBase, VectorBase, and BeetleBase. There is an ongoing initiative started in 2011 to sequence the genomes of 5,000 insects and other arthropods called the i5k. Some Lepidoptera have been genetically modified in nature by the wasp bracovirus.
Drosophila ananassae is a species of fruit fly that is a useful model organism for genetic studies because it is easily cultured in the laboratory, and was one of 12 fruitfly genomes sequenced for a large comparative study.
Drosophila grimshawi is a species of fruit fly from Hawaii, and was one of 12 fruit fly genomes sequenced for a large comparative study.
Drosophila mojavensis is a cactophilic species of fruit fly from the southwestern United States and Mexico, and was one of 12 fruitfly genomes sequenced for a large comparative study.
Drosophila persimilis is a species of fruit fly that is a sister species to D. pseudoobscura, and was one of 12 fruitfly genomes sequenced for a large comparative study.
Drosophila sechellia is a species of fruit fly, used in lab studies of speciation because it can mate with Drosophila simulans.
Drosophila virilis is a species of fruit fly with a worldwide distribution, and was one of 12 fruit fly genomes sequenced for a large comparative study. The males have bright red gonads that can be seen through the cuticle.
Drosophila yakuba is an African species of fruit fly that is predominantly found in open savanna, and was one of 12 fruit fly genomes sequenced for a large comparative study.
Peter D. Keightley FRS is Professor of Evolutionary Genetics at the Institute of Evolutionary Biology in School of Biological Sciences at the University of Edinburgh.
Scaptomyza flava is an herbivorous leaf mining fly species in the family Drosophilidae. In Latin, flava means golden or yellow. The fly is amber to dark brown in color and approximately 2.5 mm in length. In Europe and New Zealand the larvae are pests of plants in the order Brassicales, including arugula, brassicas, broccoli, Brussels sprouts, bok choy, cabbage, canola, cauliflower, horseradish, kale, kohlrabi, napa cabbage, nasturtium, radish, rapini, rutabaga, turnip, wasabi and watercress. In New Zealand, its range has expanded to include host species that are intercropped with salad brassicas, including gypsophila, otherwise known as baby's breath, which is in the pink family (Caryophyllaceae) and the pea in the Fabaceae. More typically, S. flava is oligophagous within the Brassicales. Scaptomyza are unusual within the Drospophilidae because the group includes species that are truly herbivorous. Other herbivorous drosophilids include D. suzukii, which attacks fruit very early during ripening and species within the genus Lordiphosa, from Africa and Asia, which also include leaf miners. Most drosophilids feed on microbes associated with decaying vegetation and sap fluxes.
Cyp6g1 or DDT-R is an insecticide resistance gene for DDT-resistance in Drosophila melanogaster. It belongs to the cytochrome P450 family and is located in chromosome 2R. Following up their earlier work, Daborn et al 2002 find the DDT-R gene induces overtranscription of Cyp6g1, of which there are 4 duplicates. They also find several substrates of Cyp6g1, namely DDT, lufenuron, and nitenpyram.
Insect olfactory receptors are expressed in the cell membranes of the olfactory sensory neurons of insects. Similarly to mammalian olfactory receptors, in insects each olfactory sensory neuron expresses one type of OR, allowing the specific detection of a volatile chemical. Differently to mammalian ORs, insect ORs form a heteromer with a fixed monomer, Orco, and a variable OR monomer, which confers the odour specificity.
Cytochrome P450, family 305, also known as CYP305, is an animal cytochrome P450 family found in insect genome. The first gene identified in this family is the CYP305A1 from the Drosophila melanogaster.
The Hawaiian Drosophila are a monophyletic and speciose lineage of Drosophila vinegar flies, and members of the subgenus Drosophila. Over 1000 species of Drosophila are endemic to the Hawaiian Islands. The Hawaiian Drosophila species also include the "picture-wing" clade of Drosophila, named for the intricate patterns of melanin pigment on their wings. Over 100 species belong to the picture-wing clade of flies, prompting the generation of a database devoted solely to wing diversity in the Hawaiian Drosophila lineage. The Hawaiian Drosophila species group is presently paraphyletic, as the putative Scaptomyza genus is nested within the Hawaiian Drosophila clade.
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