Eno (drug)

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Eno is an over-the-counter antacid brand produced by Haleon. Its main ingredients are sodium carbonate, sodium bicarbonate and citric acid. [1] [2] [3]

Contents

History

Eno was first marketed by James Crossley Eno (18271915). [4] Legend has it that his idea for the product arose while he was working at the pharmacy of an infirmary in Newcastle, Britain, with Dennis Embleton; Embleton often prescribed an effervescent drink made by mixing sodium bicarbonate and citric acid in water, and Eno adopted this beverage. [5] In reality, Eno opened a pharmacy where he made the mixture in 1852, a year before Embleton came to work at the infirmary, and such fruit salt mixtures were common at the time. [5]

Marketing

Eno gave away his branded mixture to sea captains at the port, and in this way Eno's became a brand known around the world. By 1865 he had to move to a bigger facility, and he formally founded the company Eno's "Fruit Salt" Works in 1868. [5] [6] [7] :253 In 1878 Eno moved the business to Hatcham where the factory employed 50 people by 1884. [8]

Eno was advertised heavily, as all patent medicines were at that time. [5] In 1883 it was advertised as a cure for cholera [9] and in 1892 for "keeping blood pure and free from disease", prevention of diarrhea, and many other conditions. [10] By 1928 the company had factories in England, Canada, France, Germany, Spain, and the US; that year the company was acquired by International Proprietaries, a company that had been established by Canadian businessman Harold F. Ritchie. [7] :253 International Proprietaries was eventually renamed Eno, and in 1938 the business was bought by Beecham [7] :253 for its products as well as its international marketing force. [11] As the pharmaceutical industry transitioned from selling cure-all patent medicines to selling drugs in the 1950s, Eno was one of a handful of products that were retained in the industry. [12] :154

Related Research Articles

In biology, homeostasis is the state of steady internal, physical, and chemical conditions maintained by living systems. This is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits. Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium, and calcium ions, as well as the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity. Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life.

<span class="mw-page-title-main">Diarrhea</span> Loose or liquid bowel movements

Diarrhea, also spelled diarrhoea or diarrhœa, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal.

<span class="mw-page-title-main">Citric acid</span> Weak organic acid

Citric acid is an organic compound with the chemical formula HOC(CO2H)(CH2CO2H)2. It is a colorless weak organic acid. It occurs naturally in citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms.

<span class="mw-page-title-main">Sodium bicarbonate</span> Chemical compound

Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. It is a salt composed of a sodium cation (Na+) and a bicarbonate anion (HCO3). Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). The natural mineral form is nahcolite. It is a component of the mineral natron and is found dissolved in many mineral springs.

<span class="mw-page-title-main">Sodium carbonate</span> Chemical compound

Sodium carbonate is the inorganic compound with the formula Na2CO3 and its various hydrates. All forms are white, odourless, water-soluble salts that yield alkaline solutions in water. Historically, it was extracted from the ashes of plants grown in sodium-rich soils. Because the ashes of these sodium-rich plants were noticeably different from ashes of wood, sodium carbonate became known as "soda ash". It is produced in large quantities from sodium chloride and limestone by the Solvay process, as well as by carbonating sodium hydroxide which is made using the Chlor-alkali process.

<span class="mw-page-title-main">Baking powder</span> Dry chemical leavening agent

Baking powder is a dry chemical leavening agent, a mixture of a carbonate or bicarbonate and a weak acid. The base and acid are prevented from reacting prematurely by the inclusion of a buffer such as cornstarch. Baking powder is used to increase the volume and lighten the texture of baked goods. It works by releasing carbon dioxide gas into a batter or dough through an acid–base reaction, causing bubbles in the wet mixture to expand and thus leavening the mixture. The first single-acting baking powder, which releases carbon dioxide at room temperature as soon as it is dampened, was developed by food manufacturer Alfred Bird in England in 1843. The first double-acting baking powder, which releases some carbon dioxide when dampened, and later releases more of the gas when heated by baking, was first developed by Eben Norton Horsford in the U.S. in the 1860s.

<span class="mw-page-title-main">Kala namak</span> Kiln-fired rock salt from South Asia

Kala namak is a kiln-fired rock salt with a sulphurous, pungent smell used in the Indian subcontinent. It is also known as "Himalayan black salt", Sulemani namak, bit noon, bire noon, bit loona, bit lobon, kala loon, sanchal, guma loon, or pada loon, and is manufactured from the salts mined in the regions surrounding the Himalayas.

<span class="mw-page-title-main">Carbonated water</span> Water containing dissolved carbon dioxide gas

Carbonated water is water containing dissolved carbon dioxide gas, either artificially injected under pressure or occurring due to natural geological processes. Carbonation causes small bubbles to form, giving the water an effervescent quality. Common forms include sparkling natural mineral water, club soda, and commercially-produced sparkling water.

The Leblanc process was an early industrial process for making soda ash used throughout the 19th century, named after its inventor, Nicolas Leblanc. It involved two stages: making sodium sulfate from sodium chloride, followed by reacting the sodium sulfate with coal and calcium carbonate to make sodium carbonate. The process gradually became obsolete after the development of the Solvay process.

<span class="mw-page-title-main">Gastric acid</span> Digestive fluid formed in the stomach

Gastric acid, gastric juice, or stomach acid is a digestive fluid formed within the stomach lining. With a pH between 1 and 3, gastric acid plays a key role in digestion of proteins by activating digestive enzymes, which together break down the long chains of amino acids of proteins. Gastric acid is regulated in feedback systems to increase production when needed, such as after a meal. Other cells in the stomach produce bicarbonate, a base, to buffer the fluid, ensuring a regulated pH. These cells also produce mucus – a viscous barrier to prevent gastric acid from damaging the stomach. The pancreas further produces large amounts of bicarbonate and secretes bicarbonate through the pancreatic duct to the duodenum to neutralize gastric acid passing into the digestive tract.

<span class="mw-page-title-main">Oral rehydration therapy</span> Type of fluid replacement used to prevent and treat dehydration

Oral rehydration therapy (ORT) is a type of fluid replacement used to prevent and treat dehydration, especially due to diarrhea. It involves drinking water with modest amounts of sugar and salts, specifically sodium and potassium. Oral rehydration therapy can also be given by a nasogastric tube. Therapy should routinely include the use of zinc supplements. Use of oral rehydration therapy has been estimated to decrease the risk of death from diarrhea by up to 93%.

<span class="mw-page-title-main">Ringer's lactate solution</span> Fluid used for resuscitation after blood loss

Ringer's lactate solution (RL), also known as sodium lactate solution,Lactated Ringer’s, and Hartmann's solution, is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water. It is used for replacing fluids and electrolytes in those who have low blood volume or low blood pressure. It may also be used to treat metabolic acidosis and to wash the eye following a chemical burn. It is given by intravenous infusion or applied to the affected area.

<span class="mw-page-title-main">Bath bomb</span> Effervescent bathing product

A bath bomb is a consumer product used during bathing. It was invented and patented in 1989 by Mo Constantine, co-founder of Lush Cosmetics. It is a compacted mixture of wet and dry ingredients molded into any of several shapes and then dried. Bath water effervesces at the surface of a bath bomb immersed within it, with attendant dispersion of such ingredients as essential oil, moisturizer, scent, or colorant.

<span class="mw-page-title-main">Metabolic alkalosis</span> Medical condition

Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35–7.45). This is the result of decreased hydrogen ion concentration, leading to increased bicarbonate, or alternatively a direct result of increased bicarbonate concentrations. The condition typically cannot last long if the kidneys are functioning properly.

<span class="mw-page-title-main">Creamola Foam</span>

Creamola Foam was a soft drink produced in the form of effervescent crystals that were mixed with water. It was manufactured in Glasgow and sold in the UK from the 1950s, until Nestlé ended production in October 1998.

<span class="mw-page-title-main">Monosodium citrate</span> Chemical compound

Monosodium citrate, more correctly, sodium dihydrogen citrate (Latin: natrium citricum acidulatum), is an acid salt of citric acid. Disodium citrate and trisodium citrate are also known. It can be prepared by partial neutralisation of citric acid with an aqueous solution of sodium bicarbonate or carbonate. It has a slightly acidic taste.

Sodium citrate may refer to any of the sodium salts of citric acid :

<span class="mw-page-title-main">Andrews Liver Salts</span>

Andrews Liver Salts is a laxative and antacid for mild stomach complaints. It is sold as a powder which is added to water and mixed, creating effervescence, before being swallowed. The powder contains sugar; an antacid, sodium bicarbonate ; citric acid ; and a laxative, magnesium sulphate. The product is similar to Eno's salts and Kruschen salts, and a mild form of Epsom salts. The term "liver salts" or "health salts" is typically used for a laxative.

James Crossley Eno was a 19th-century British pharmacist known for compounding and selling a brand of fruit salt that is still popular today as an antacid.

A fruit salt or fruit salts is an effervescent compound made up of organic acids such as citric acid or tartaric acid and salts such as sodium bicarbonate, sodium carbonate, or sodium bitartrate in combination with added flavoring and sugar. Historically, fruit salts were sold for a wide range of ailments, and today they are used primarily as antacids.

References

  1. "About Us, Indigestion And Heartburn Relief ENO". GlaxoSmithKline Canada.
  2. "Eno's Fruit Salt". The Quack Doctor. 17 July 2009.
  3. "Eno – Summary of Product Characteristics at eMC". Electronic Medicines Compendium. Retrieved 2 September 2016. Last updated 1 January 2016
  4. "James Crossley Eno". Geni.
  5. 1 2 3 4 W. A. Campbell (June, 1966) James Crossley Eno and the Rise of the Health Salts Trade. University of Newcastle Upon Tyne Medical Gazette 60(3):350 Reprinted as an appendix to W. A. Campbell. The Analytical Chemist In Nineteenth Century English Social History Thesis presented for the degree of Master of Letters in the University of Durham. Newcastle upon Tyne July 1971
  6. Russell, Colin A., ed. (1999). Chemistry, society and environment : a new history of the British chemical industry. Cambridge: Royal Society of Chemistry. p. 137. ISBN   9780854045990.
  7. 1 2 3 Wilkins, Mira (2004). The history of foreign investment in the United States, 1914–1945 . Cambridge, Mass: Harvard University Press. ISBN   9780674045187.
  8. Dews, Nathan (1884). The History of Deptford (2nd ed.). Simpkin, Marshall, & Co. pp. 273–274.
  9. Kotar, S. L.; Gessler, J. E. (2014). Cholera a worldwide history. Jefferson, NC: McFarland. p. 242. ISBN   9781476613642.
  10. Advertisement for ENO. The Sunday Magazine (magazine), Collected issues of 1892. Strahan & Company, p. 892. Quote: "Drawing an Overdraft on the Bank of Life. Late Hours, Fagged, Unnatural Excitement, Breathing Impure Air, too Rich Food, Alcoholic Drink, Gouty, Rheumatic, and other Blood Poisons, Fevers, Feverish Colds, Influenza, Sleeplessness, Biliousness, Sick Headache, Skin Eruptions, Pimples on the Face, Want of Appetite, Sourness of Stomach, etc. It prevents Diarrhoea, and removes it in the early stages. Use ENO's "FRUIT SALT" It is Pleasant, Cooling, Health-Giving, Refreshing, and Invigorating. You cannot overstate its great value in keeping the Blood Pure and free from Disease. TO ALL LEAVING HOME FOR A CHANGE. – Don't go without a bottle of ENO's "FRUIT SALT". It prevents any over-acid state of the blood. It should be kept in every bedroom, in readiness for any emergency. Be careful to avoid rash acidulated salines, and use ENO's "FRUIT SALT" to prevent the bile becoming too thick and (impure) producing a gummy, viscous, clammy stickiness or adhesiveness in the mucous membrane or the intestinal canal, frequently the pivot of diarrhoea and disease. ENO's "FRUIT SALT" prevents and removes diarrhoea in the early stages. Without such a simple precaution the jeopardy of life is immensely increased. There is no doubt that where it has been taken in the earliest stages of a disease it has in many instances prevented what would otherwise have been a severe illness."
  11. Tedlow, Richard S.; Jones, Geoffrey G. (2014). The Rise and Fall of Mass Marketing (RLE Marketing) Volume 25 of Routledge Library Editions: Marketing. Routledge. pp. 110–111. ISBN   9781317663010.
  12. Crellin, John K. (2004). A social history of medicines in the twentieth century : to be taken three times a day (Reprint. ed.). New York: Pharmaceutical Products Press. ISBN   9780789018458.