 | |
| Product type | Antacid |
|---|---|
| Owner | Haleon |
| Country | United States |
| Introduced | 1930 |
| Previous owners |
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| Website | www |
Tums (stylized as TUMS) is an antacid made of sucrose (table sugar) and calcium carbonate (CaCO3) manufactured by Haleon in St. Louis, Missouri, US. They are also available in a sugar-free version. It is an over-the-counter drug, available at many retail stores, including drug stores, grocery stores and mass merchandisers. It provides relief from heartburn and indigestion ("sour stomach").
In 1928, James Harvey "Jim" Howe (born 1873 College Corner, Ohio, and died 1960 Webster Groves, Missouri), a pharmacist in St. Louis, Missouri, developed Tums in the basement of his home while treating his wife's indigestion. The remedy caught on, and commercial production began in 1930 by the Lewis-Howe Company, which took its name from Howe and his uncle, A. H. Lewis, who was a pharmacist in Bolivar, Missouri; Howe worked in his uncle's drugstore as a teenager.[ citation needed ] Tums were named in 1930 after a radio contest, which was won by a nurse who came up with the phrase "Tums for the Tummy." [1]
In 1978 the company was purchased by Revlon of New York, making it no longer a St. Louis–based company. Revlon's Norcliff Thayer unit oversaw the Tums brand. Revlon spun Norcliff Thayer off to the British Beecham Group in 1986, and Beecham eventually became GlaxoSmithKline through a series of mergers.
Since 1930, a plant originally built by Lewis-Howe in downtown St. Louis has been making the antacid tablets. [2] The factory complex remains the main manufacturing site for Tums, and GlaxoSmithKline completed millions of dollars' worth of renovations and modernizations during the 2000s decade. [3] [4]
Since Tums is an over-the-counter drug, it is not considered a pharmaceutical-grade treatment (does not require a prescription). Prescription strength acid reflux medications often contain proton-pump inhibitors (PPI) or histamine H2 receptor blockers (H2 blockers, H2 antagonists). [5]
Famous advertising campaigns for Tums have included "Tums for the Tummy" and, much later for television in the 1970s, "Mother Tums" ("There, there!"), and since 1981, a barbershop jingle sung to the theme music used in all versions of the TV crime drama series Dragnet . [6]
Tums comes in chewable tablets that are taken orally. It is also available in different flavors such as peppermint and fruit flavors such as berry, orange, and cherry. [7]
An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. Some antacids have been used in the treatment of constipation and diarrhea. Marketed antacids contain salts of aluminum, calcium, magnesium, or sodium. Some preparations contain a combination of two salts, such as magnesium carbonate and aluminum hydroxide.
GSK plc is a British multinational pharmaceutical and biotechnology company with global headquarters in London. It was established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham, which was itself a merger of a number of pharmaceutical companies around the Smith, Kline & French firm.
Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid into the esophagus. It is the major symptom of gastroesophageal reflux disease (GERD).
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. Symptoms include dental corrosion, dysphagia, heartburn, odynophagia, regurgitation, non-cardiac chest pain, extraesophageal symptoms such as chronic cough, hoarseness, reflux-induced laryngitis, or asthma. In the long term, and when not treated, complications such as esophagitis, esophageal stricture, and Barrett's esophagus may arise.
H2 antagonists, sometimes referred to as H2RAs and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and gastroesophageal reflux disease. They have been surpassed by proton pump inhibitors (PPIs). The PPI omeprazole was found to be more effective at both healing and alleviating symptoms of ulcers and reflux oesophagitis than the H2 blockers ranitidine and cimetidine.
Lucozade is a British brand of soft drinks and energy drinks manufactured and marketed by the Japanese company Suntory. Created as "Glucozade" in the UK in 1927 by a Newcastle pharmacist, William Walker Hunter, it was acquired by the British pharmaceutical company Beecham's in 1938 and sold as Lucozade, an energy drink for the sick. Its advertising slogan was "Lucozade aids recovery". It was sold mostly in pharmacies up until the 1980s before it was more readily available as a sports drink in shops across the UK.
Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.
Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production. It is mainly used in the treatment of heartburn and peptic ulcers.
Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana, United States. Alka-Seltzer contains three active ingredients: aspirin (ASA), sodium bicarbonate, and anhydrous citric acid. The aspirin is a pain reliever and anti-inflammatory, the sodium bicarbonate is an antacid, and the citric acid reacts with the sodium bicarbonate and water to form effervescence.
Ranitidine, previously sold under the brand name Zantac among others, is a medication used to decrease stomach acid production. It was commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. It can be given by mouth, injection into a muscle, or injection into a vein.
Maalox was a brand of antacid owned by Sanofi. Their main product is a flavored liquid containing a suspension of aluminum hydroxide and magnesium hydroxide, which act to neutralize or reduce stomach acid, for the purpose of relieving the symptoms of indigestion, heartburn, gastroesophageal reflux disease, and also stomach or duodenal ulcers. It also contains simethicone, an anti-foaming agent which helps eliminate bloating from gas. In large doses, the medicine can act as a laxative. The trademark is owned by Novartis International AG, and was first produced commercially in 1949.
Eno is an over-the-counter antacid brand produced by Haleon. Its main ingredients are sodium carbonate, sodium bicarbonate and citric acid.
Risedronic acid, often used as its sodium salt risedronate sodium, is a bisphosphonate. It slows down the cells which break down bone. It's used to treat or prevent osteoporosis, and treat Paget's disease of bone. It is taken by mouth.
Sensodyne is a brand name of toothpaste and mouthwash targeted at people with sensitive teeth. Sensodyne is owned by Haleon and is marketed under the name Shumitect in Japan.
The Beecham Group plc was a British pharmaceutical company. It was once a constituent of the FTSE 100 Index. Founded by Thomas Beecham who opened the first factory in St Helens, Lancashire in 1859, Beecham focused on marketing the business by advertising in newspapers and using a network of wholesale agents in northern England and in London, rapidly building up the business. In August 1859 he created the slogan for Beecham's Pills: "Worth a guinea a box", considered to be the world's first advertising slogan, which helped the business become a global brand.
The pharmaceutical industry in the United Kingdom directly employs around 73,000 people and in 2007 contributed £8.4 billion to the UK's GDP and invested a total of £3.9 billion in research and development. In 2007 exports of pharmaceutical products from the UK totalled £14.6 billion, creating a trade surplus in pharmaceutical products of £4.3 billion.
Magnesium salts are available as a medication in a number of formulations. They are used to treat magnesium deficiency, low blood magnesium, eclampsia, and several other conditions. Magnesium is an essential nutrient.
James Crossley Eno was a British pharmacist known for compounding and selling a brand of fruit salt that is still popular today as an antacid.
A fruit salt or fruit salts is an effervescent compound made up of organic acids such as citric acid or tartaric acid and salts such as sodium bicarbonate, sodium carbonate, or sodium bitartrate in combination with added flavoring and sugar. Historically, fruit salts were sold for a wide range of ailments, and today they are used primarily as antacids.
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary symptoms.
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