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Names | |
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Preferred IUPAC name Imidazolidine-2-thione | |
Other names 1,3-Ethylene-2-thiourea, N,N-Ethylenethiourea | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.002.280 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C3H6N2S | |
Molar mass | 102.16 g·mol−1 |
Appearance | White solid |
Odor | Faint, amine-like |
Melting point | 203 °C (397 °F; 476 K) |
Boiling point | 347.18 °C (656.92 °F; 620.33 K) |
2% (30 °C) [1] | |
Vapor pressure | 16 mmHg (20 °C) [1] |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards | combustible [1] |
Flash point | 252.2 °C (486.0 °F; 525.3 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 1832 mg/kg (oral, rat) [2] |
NIOSH (US health exposure limits): | |
PEL (Permissible) | None [1] |
REL (Recommended) | Ca Use encapsulated form. [1] |
IDLH (Immediate danger) | Ca [N.D.] [1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Ethylene thiourea (ETU) is an organosulfur compound with the formula C3H6N2S. It is an example of an N,N-disubstituted thiourea. It is a white solid. It is synthesized by treating ethylenediamine with carbon disulfide. [3]
Ethylene thioureas are an excellent accelerant of vulcanization of neoprene rubbers. In commercial use is the N,N'-diphenylethylenethiourea. Due to reproductive toxicity, carcinogenicity, and mutagenicity, alternatives are being sought to the ethylenethioureas. One candidate replacement is N-methyl-2-thiazolidinethione. [4]
Ethylene thiourea can be used as a biomarker of exposure to ethylenebisdithiocarbamates (EBDTCs), which are frequently employed as fungicides in agriculture, mainly on fruits, vegetables and ornamental plants. [5]
EPA (United States Environmental Protection Agency) has classified ethylene thiourea as a Group B2, probable human carcinogen. [6] Ethylene thiourea has been shown to be a potent teratogen (causes birth defects) in rats orally or dermally exposed.
ethylene thiourea.