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Names | |
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Preferred IUPAC name 5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.018.175 |
EC Number |
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KEGG | |
MeSH | C014547 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C5H5Cl3N2OS | |
Molar mass | 247.52 g·mol−1 |
Appearance | Pure samples are colourless and odourless; impure samples take on a pale yellow appearance with a mild, persistent odour |
Density | 1.497 g cm−3 [1] |
Melting point | 22 °C (72 °F; 295 K) |
Boiling point | 95 °C (203 °F; 368 K) at 1 mmHg |
0.117 g dm−3 | |
log P | 3.37 |
Vapor pressure | 0.011 mmHg/1.43 Pa at 25°C |
Acidity (pKa) | 2.27 |
Hazards | |
Flash point | 154.5 °C (310.1 °F; 427.6 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 1028 mg/kg (rat, oral) 2000 mg/kg (mouse, oral) 779 mg/kg (rabbit, oral) 1700 mg/kg (rabbit, dermal) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Etridiazole is a fungicide and pesticide used for prevention of pythium ultimum on cotton plants. [2]
Etridiazole can be synthesised from acetonitrile as follows:
It can also be is produced by the reaction of trichloroacetamidine hydrochloride with trichloromethanesulfenyl chloride, and then with sodium hydroxide in ethanol. [3]
Etridiazole is stable under normal conditions, [4] but degrades upon continuous exposure to sunlight, [5] and is hydrolysed by alkalis. [6] When heated to decomposition, it emits toxic fumes of hydrogen chloride, sulfur oxides, and nitrogen oxides. [7]
Etridiazole has been classified as a Group B2 Probable Human Carcinogen. [8]
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Azoxystrobin is a broad spectrum systemic fungicide widely used in agriculture to protect crops from fungal diseases. It was first marketed in 1996 using the brand name Amistar and by 1999 it had been registered in 48 countries on more than 50 crops. In the year 2000 it was announced that it had been granted UK Millennium product status.
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