Ewart R. Carson | |
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Nationality | British |
Occupation(s) | Engineer, system scientist, author, and academic |
Academic background | |
Education | BSc in Applied Science (Electrical Engineering) MSc in Instrument & Control Engineering PhD in Systems Science |
Alma mater | University of St Andrews City University London |
Thesis | Aspects of Dynamics, Control and Identification of Metabolic Systems |
Academic work | |
Institutions | City,University of London |
Ewart R Carson is a British chartered engineer,system scientist,author,and academic. He is a Professor Emeritus of Systems Science in the School of Science and Technology at City,University of London. [1]
Carson is most known for his research in the field of systems engineering with a focus in the application of systems thinking and modelling to complex social and medical issues,such as health resource management,telemedicine,and other clinical applications. He has authored and edited thirteen books including Dealing with Medical Knowledge,Modelling Methodology in Physiology and Medicine,and Decisions,Computers and Medicines:The Informatics of Pharmacotherapy.
Carson is a Fellow of the Institution of Engineering &Technology,International Academy of Medical and Biological Engineering [2] and the American Institute of Medical &Biological Engineers. He is also a Life Fellow of the Institute of Electrical and Electronics Engineers (US),a Foundation Fellow of the European Alliance for Medical &Biological Engineering and Science, [3] and an Honorary Member of the Royal College of Physicians (London). He is Associate Editor of Computer Methods and Programs in Biomedicine, [4] and serves on the editorial board of the International Journal of Health Geographics. [5]
Carson was born on 11 August 1943,in Liverpool. After completing his early education at Mosspits Lane School in Liverpool and then Liverpool College, [6] he enrolled at the University of St Andrews and received his BSc in Applied Science with majors in Electrical Engineering. He then pursued further education at City,University of London,where he obtained his MSc in Instrument &Control Engineering,and PhD in Systems Science. His dissertation was titled "Aspects of Dynamics,Control,and Identification of Metabolic Systems". Later in his career,he was awarded a DSc in Measurement &Information in Medicine. [3]
Carson started his professional career as an engineer in the Computer Applications Laboratory at the Philips Electronics Company. Later he moved to academia at what is now City,University of London, [7] becoming a Professor of Systems Science in the Department of Systems Science. During his career,he contributed in the development of several graduate and post-graduate programmes in Biomedical Engineering and related subjects. He is currently serving as a Professor Emeritus at City,University of London. [1]
Carson was the Director of the Centre for Measurement and Information in Medicine and the Director of the Institute of Health Sciences at City,University of London. [8] He served as an Executive Committee Member at the British Medical Informatics Society and an Expert Reviewer for the European Commission. He chaired the International Measurement Confederation (IMEKO) Technical Committee on Measurement in Medicine and Biology, [9] the International Federation of Automatic Control (IFAC) Technical Committee on Biomedical Modelling and Control. [10] and the Professional Network in Healthcare Technologies at the Institution of Engineering and Technology. He had involvement with all three of these professional bodies for over 20 years. [2]
Carson's research has focused on the development and evaluation of systems with an emphasis on medicine and healthcare. At the beginning of his academic career,he did research on the development of mathematical models to better understand the dynamics of metabolic processes taking place in the human body. He also conducted research for the development of diabetic advisory systems. [11]
Other major areas of research include health resource management,integrated policy modelling,healthcare technologies,modelling in physiology and medicine,and clinical decision support. [12] He has published more than 300 peer-reviewed articles in journals. [13]
Carson has developed a range of mathematical models for human metabolic systems including plasma proteins,thyroid hormones [14] and glucose, [15] which helped in enhancing understanding of dynamics and control in quantitative terms. Apart from that he has developed models of the cardiovascular, [16] respiratory, [17] renal [18] and liver organ systems to provide an understanding in quantitative terms of a number of the underlying control processes. [19]
In addition to his research on organ systems,Carson has also worked on investigating the complex dynamics of diabetes, [15] which evolved into the development of modelling approaches designed to assist insulin dosage adjustment for type 1 diabetes. [20] Approaches included differential equation modelling, [21] rule-based expert systems and Bayesian modelling for this purpose. [22] He has also contributed his research expertise in the intensive care unit by collecting and analysing data from monitoring systems and,using machine learning and data mining to extract clinically useful information out of these data to predict future trends. [23]
Carson uses systems science to develop models that can facilitate adoption in broader areas of science. One particular application area is the field of telemedicine which combines medical knowledge with technology. As a systems scientist,he proposed a systemic framework for the assessment and evaluation of telemedicine and telecare,taking account of a wide range of impacts. [24] He has developed several systems to assist smooth transmission of health status regarding blood glucose levels,blood pressure,sleep patterns etc. of patients with chronic disease from their home to hospital via a small computer device to avoid travel. Based on the data received,patients would receive appropriate clinical advice if required. [25] Using a systemic approach,he developed a telemedicine system for home haemodialysis. [26]
Carson has applied physiological and medical modelling to develop methodologies that can be utilised across a range of domains. In his book Introduction to Modeling in Physiology and Medicine (co-authored with Claudio Cobelli) he described the fundamental principles required for good modelling methodologies to ensure that mathematical models are fit for their particular purpose. He has also provided guidelines on basic approaches to modelling,emphasising non-linear,stochastic and Bayesian formulations [27] including a model of insulin action during a meal/oral glucose tolerance test,a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. In his collaborative work on evaluating different models for fluid electrolyte equilibrium,he elucidated that features of all these models,integrated into a single implementation,could provide a system of practical clinical value. [28]
Hypoglycemia,also spelled hypoglycaemia or hypoglycæmia,sometimes called low blood sugar,is a fall in blood sugar to levels below normal,typically below 70 mg/dL (3.9 mmol/L). Whipple's triad is used to properly identify hypoglycemic episodes. It is defined as blood glucose below 70 mg/dL (3.9 mmol/L),symptoms associated with hypoglycemia,and resolution of symptoms when blood sugar returns to normal. Hypoglycemia may result in headache,tiredness,clumsiness,trouble talking,confusion,fast heart rate,sweating,shakiness,nervousness,hunger,loss of consciousness,seizures,or death. Symptoms typically come on quickly.
Blood glucose monitoring is the use of a glucose meter for testing the concentration of glucose in the blood (glycemia). Particularly important in diabetes management,a blood glucose test is typically performed by piercing the skin to draw blood,then applying the blood to a chemically active disposable 'test-strip'. The other main option is continuous glucose monitoring (CGM). Different manufacturers use different technology,but most systems measure an electrical characteristic and use this to determine the glucose level in the blood. Skin-prick methods measure capillary blood glucose,whereas CGM correlates interstitial fluid glucose level to blood glucose level. Measurements may occur after fasting or at random nonfasting intervals,each of which informs diagnosis or monitoring in different ways.
Medical physics deals with the application of the concepts and methods of physics to the prevention,diagnosis and treatment of human diseases with a specific goal of improving human health and well-being. Since 2008,medical physics has been included as a health profession according to International Standard Classification of Occupation of the International Labour Organization.
Medical anthropology studies "human health and disease,health care systems,and biocultural adaptation". It views humans from multidimensional and ecological perspectives. It is one of the most highly developed areas of anthropology and applied anthropology,and is a subfield of social and cultural anthropology that examines the ways in which culture and society are organized around or influenced by issues of health,health care and related issues.
Health informatics combines communications,information technology (IT),and health care to enhance patient care and is at the forefront of the medical technological revolution. It can be viewed as a branch of engineering and applied science.
Systems science,also referred to as systems research or simply systems,is a transdisciplinary field that is concerned with understanding simple and complex systems in nature and society,which leads to the advancements of formal,natural,social,and applied attributions throughout engineering,technology and science,itself.
Virtual reality in telerehabilitation is a method used first in the training of musculoskeletal patients using asynchronous patient data uploading,and an internet video link. Subsequently,therapists using virtual reality-based telerehabilitation prescribe exercise routines via the web which are then accessed and executed by patients through a web browser. Therapists then monitor the patient's progress via the web and modify the therapy asynchronously without real-time interaction or training.
Automated insulin delivery systems are automated systems designed to assist people with insulin-requiring diabetes,by automatically adjusting insulin delivery in response to blood glucose levels. Currently available systems can only deliver a single hormone—insulin. Other systems currently in development aim to improve on current systems by adding one or more additional hormones that can be delivered as needed,providing something closer to the endocrine functionality of the pancreas.
Amar Gupta is an Indian computer scientist based in the United States. Gupta has worked in academics,private companies,and international organizations in positions that involved analysis and leveraging of opportunities at the intersection of technology and business,as well as the design,development,and implementation of prototype systems that led to widespread adoption of new techniques and technologies.
Computer-aided detection (CADe),also called computer-aided diagnosis (CADx),are systems that assist doctors in the interpretation of medical images. Imaging techniques in X-ray,MRI,endoscopy,and ultrasound diagnostics yield a great deal of information that the radiologist or other medical professional has to analyze and evaluate comprehensively in a short time. CAD systems process digital images or videos for typical appearances and to highlight conspicuous sections,such as possible diseases,in order to offer input to support a decision taken by the professional.
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V. Mohan is an Indian physician/scientist specializing in diabetology. He is the Chairman of Dr. Mohan’s Diabetes Specialities Centre,which is an IDF Centre of Excellence in Diabetes Care. He is also the Chairman of the Madras Diabetes Research Foundation in Chennai which is an ICMR Centre for Advanced Research on Diabetes.
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Jasjit S. Suri is an American engineer who works in the fields of biomedical engineering,computer science and clinical engineering. His work is focused on the implementation of artificial intelligence in biomedicine,and healthcare.
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