The Ferrier Lecture is a Royal Society lectureship given every three years "on a subject related to the advancement of natural knowledge on the structure and function of the nervous system". [1] It was created in 1928 to honour the memory of Sir David Ferrier, a neurologist who was the first British scientist to electronically stimulate the brain for the purpose of scientific study. [1]
In its 90-year history, the Lecture has been given 30 times. It has never been given more than once by the same person. The first female to be awarded the honour was Prof. Christine Holt in 2017. The first lecture was given in 1929 by Charles Scott Sherrington, and was titled "Some functional problems attaching to convergence". [2] The most recent lecturer was provided by Prof. Christine Holt, who presented a lecture in 2017 titled "understanding of the key molecular mechanisms involved in nerve growth, guidance and targeting which has revolutionised our knowledge of growing axon tips". [3] In 1971, the lecture was given by two individuals (David Hunter Hubel and Torsten Nils Wiesel) on the same topic, with the title "The function and architecture of the visual cortex". [2]
Year | Name | Lecture title | Notes |
---|---|---|---|
1929 | Charles Scott Sherrington | "Some functional problems attaching to convergence" | [4] |
1932 | C. U. Ariëns Kappers | "Some correlations between skull and brain" | [5] |
1935 | Otto Loewi | "Problems connected with the principle of humeral transmission of nervous impulses" | – |
1938 | Edgar Douglas Adrian | "Some problems of localization in the central nervous system" | [6] |
1941 | Frederic Charles Bartlett | "Fatigue following highly skilled work" | [7] |
1944 | Gordon Morgan Holmes | "The organization of the visual cortex in man" | [8] |
1947 | Wilder Penfield | "Some observations of the cerebral cortex of Man" | [9] |
1950 | John Zachary Young | "Growth and plasticity in the nervous system" | – |
1953 | Francis Martin Rouse Walshe | "The contribution of clinical observation to cerebral physiology" | [10] |
1956 | Wilfrid Edward Le Gros Clark | "Inquiries into the anatomical basis of olfactory discrimination" | [11] |
1959 | John Carew Eccles | "The nature of central inhibitory action" | [12] |
1962 | William Albert Hugh Rushton | "Visual adaptation" | [13] |
1965 | Stephen William Kuffler | "Physiological properties of vertebrate and invertebrate neurological cells and the movement of substances through the nervous system" | [14] |
1968 | Charles Garrett Phillips | "Studies of a primates brain and hand" | [15] |
1971 | David Hunter Hubel and Torsten Nils Wiesel | "The function and architecture of the visual cortex" | [16] |
1974 | Wilhelm Siegmund Feldberg | "Body temperature and fever, changes in our views during the last decade" | [17] |
1977 | Janos Szentagothai | "The neuron network of the cerebral cortex, a functional interpretation" | [18] |
1980 | Horace Basil Barlow | "Cerebral cortex and the design of the eye" | – |
1983 | Leslie Lars Iversen | "Amino acids and peptides: fast and slow chemical signals in the nervous system" | – |
1986 | Giles Brindley | "The actions of parasympathetic and sympathetic nerves in human micturition, erection and seminal emission, and their restoration in paraplegic patients by implanted electrical stimulators" | – |
1989 | Lawrence Weiskrantz | "Side glances at blindsight, recent approaches to implicit discrimination in human cortical blindness" | [19] |
1992 | Gerald Westheimer | "Seeing depth with two eyes, stereopsis" | [20] |
1995 | Semir Zeki | "Behind the scene: an exploration of the visual brain" | [21] |
1998 | Jean-Pierre Changeux | "The nicotinic acetylcholine receptor and synaptic plasticity" | [22] |
2001 | Andrew Lumsden | "Patterning the embryonic brain" | – |
2004 | Alan Cowey | "Magnetic brain stimulation: what can it tell us about brain function?" | [23] |
2007 | Marc Tessier-Lavigne | "Brain development and brain repair: Molecules and mechanisms that control neuronal wiring" | – |
2010 | Colin Blakemore | "Plasticity of the brain: the key to human development, cognition and evolution" | [24] |
2013 | John O'Keefe | "cognitive neuroscience, especially on the role of the hippocampus, and the mechanisms supporting memory and cognition" | [25] |
2017 | Christine Holt | "understanding of the key molecular mechanisms involved in nerve growth, guidance and targeting which has revolutionised our knowledge of growing axon tips" | [26] |
2019 | Ray Dolan | "for his work charting the brain activity related to fundamental aspects of human conduct and behaviour" | [27] |
2021 | Daniel Wolpert | "for groundbreaking contributions to our understanding of how the brain controls movement. Using theoretical and experimental approaches he has elucidated the computational principles underlying skilled motor behaviour." | [28] |
2023 | Richard G. Morris | "for greatly advancing the understanding of the physiological and psychological processes underlying memory." | [29] |
2025 | Gillian Bates | "for her work in understanding the molecular basis of Huntington’s disease and consistently producing highly impactful findings which have moulded the course of this field." | [30] |
Neuroscience is the scientific study of the nervous system, its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences.
Roger Wolcott Sperry was an American neuropsychologist, neurobiologist, cognitive neuroscientist, and Nobel laureate who, together with David Hunter Hubel and Torsten Nils Wiesel, won the 1981 Nobel Prize in Physiology and Medicine for his work with split-brain research. A Review of General Psychology survey, published in 2002, ranked Sperry as the 44th most cited psychologist of the 20th century.
Sir Andrew Fielding Huxley was an English physiologist and biophysicist. He was born into the prominent Huxley family. After leaving Westminster School in central London, he went to Trinity College, Cambridge, on a scholarship, after which he joined Alan Hodgkin to study nerve impulses. Their eventual discovery of the basis for propagation of nerve impulses earned them the Nobel Prize in Physiology or Medicine in 1963. They made their discovery from the giant axon of the Atlantic squid. Soon after the outbreak of the Second World War, Huxley was recruited by the British Anti-Aircraft Command and later transferred to the Admiralty. After the war he resumed research at the University of Cambridge, where he developed interference microscopy that would be suitable for studying muscle fibres.
Computational neuroscience is a branch of neuroscience which employs mathematics, computer science, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system.
Margaret Stratford Livingstone is the Takeda Professor of Neurobiology in the Department of Neurobiology at Harvard Medical School in the field of visual perception. She authored the book Vision and Art: The Biology of Seeing. She was elected a member of the American Academy of Arts and Sciences in 2015 and was elected to the National Academy of Sciences in 2020.
The nigrostriatal pathway is a bilateral dopaminergic pathway in the brain that connects the substantia nigra pars compacta (SNc) in the midbrain with the dorsal striatum in the forebrain. It is one of the four major dopamine pathways in the brain, and is critical in the production of movement as part of a system called the basal ganglia motor loop. Dopaminergic neurons of this pathway release dopamine from axon terminals that synapse onto GABAergic medium spiny neurons (MSNs), also known as spiny projection neurons (SPNs), located in the striatum.
Torsten Nils Wiesel is a Swedish neurophysiologist. With David H. Hubel, he received the 1981 Nobel Prize in Physiology or Medicine, for their discoveries concerning information processing in the visual system; the prize was shared with Roger W. Sperry for his independent research on the cerebral hemispheres.
David Hunter Hubel was an American Canadian neurophysiologist noted for his studies of the structure and function of the visual cortex. He was co-recipient with Torsten Wiesel of the 1981 Nobel Prize in Physiology or Medicine, for their discoveries concerning information processing in the visual system. For much of his career, Hubel worked as the Professor of Neurobiology at Johns Hopkins University and Harvard Medical School. In 1978, Hubel and Wiesel were awarded the Louisa Gross Horwitz Prize from Columbia University. In 1983, Hubel received the Golden Plate Award of the American Academy of Achievement.
John Zachary Young FRS, generally known as "JZ" or "JZY", was an English zoologist and neurophysiologist, described as "one of the most influential biologists of the 20th century".
Vernon Benjamin Mountcastle was an American neurophysiologist and Professor Emeritus of Neuroscience at Johns Hopkins University. He discovered and characterized the columnar organization of the cerebral cortex in the 1950s. This discovery was a turning point in investigations of the cerebral cortex, as nearly all cortical studies of sensory function after Mountcastle's 1957 paper, on the somatosensory cortex, used columnar organization as their basis.
Sir Colin Blakemore,, Hon was a British neurobiologist, specialising in vision and the development of the brain. He was Yeung Kin Man Professor of Neuroscience and senior fellow of the Hong Kong Institute for Advanced Study at City University of Hong Kong. He was a distinguished senior fellow in the Institute of Philosophy, School of Advanced Study, University of London and Emeritus Professor of Neuroscience at the University of Oxford and a past Chief Executive of the British Medical Research Council (MRC). He was best known to the public as a communicator of science but also as the target of a long-running animal rights campaign. According to The Observer, he was both "one of the most powerful scientists in the UK" and "a hate figure for the animal rights movement".
Retinotopy is the mapping of visual input from the retina to neurons, particularly those neurons within the visual stream. For clarity, 'retinotopy' can be replaced with 'retinal mapping', and 'retinotopic' with 'retinally mapped'.
Stephen William Kuffler was a Hungarian-American neurophysiologist. He is often referred to as the "Father of Modern Neuroscience". Kuffler, alongside noted Nobel Laureates Sir John Eccles and Sir Bernard Katz gave research lectures at the University of Sydney, strongly influencing its intellectual environment while working at Sydney Hospital. He founded the Harvard neurobiology department in 1966, and made numerous seminal contributions to our understanding of vision, neural coding, and the neural implementation of behavior. He is known for his research on neuromuscular junctions in frogs, presynaptic inhibition, and the neurotransmitter GABA. In 1972, he was awarded the Louisa Gross Horwitz Prize from Columbia University.
Pasko Rakic is a Yugoslav-born American neuroscientist, who presently works in the Yale School of Medicine Department of Neuroscience in New Haven, Connecticut. His main research interest is in the development and evolution of the human brain. He was the founder and served as Chairman of the Department of Neurobiology at Yale, and was founder and Director of the Kavli Institute for Neuroscience. He is best known for elucidating the mechanisms involved in development and evolution of the cerebral cortex. In 2008, Rakic shared the inaugural Kavli Prize in Neuroscience. He is currently the Dorys McConell Duberg Professor of Neuroscience, leads an active research laboratory, and serves on Advisory Boards and Scientific Councils of a number of Institutions and Research Foundations.
Geoffrey Burnstock was a neurobiologist and President of the Autonomic Neuroscience Centre of the UCL Medical School. He is best known for coining the term purinergic signalling, which he discovered in the 1970s. He retired in October 2017 at the age of 88.
Andrew Gino Lumsden is an English neurobiologist, Emeritus Professor of the University of London and founder in 2000 of the Medical Research Council Centre for Developmental Neurobiology at King's College London.
Christine Elizabeth Holt is a British developmental neuroscientist.
Daniel Mark Wolpert FRS FMedSci is a British medical doctor, neuroscientist and engineer, who has made important contributions in computational biology. He was Professor of Engineering at the University of Cambridge from 2005, and also became the Royal Society Noreen Murray Research Professorship in Neurobiology from 2013. He is now Professor of Neurobiology at Columbia University.
John Graham Nicholls FRS was a British, American and Swiss physiologist and neuroscientist.
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