Marc Tessier-Lavigne | |
---|---|
11th President of Stanford University | |
In office September 1, 2016 –August 31, 2023 | |
Preceded by | John L. Hennessy |
Succeeded by | Richard Saller |
10th President of Rockefeller University | |
In office 2011–2016 | |
Preceded by | Paul Nurse |
Succeeded by | Richard P. Lifton |
Personal details | |
Born | Marc Trevor Tessier-Lavigne December 18,1959 Trenton,Ontario,Canada |
Nationality | Canada United States |
Children | 3 |
Education | McGill University (BS) New College,Oxford (BA) University College London (PhD) |
Scientific career | |
Fields | Neuroscience |
Institutions | University of California,San Francisco Genentech Rockefeller University Stanford University |
Thesis | Processing of Signals and Noise in the Outer Retina of the Salamander (1987) |
Doctoral advisor | David Attwell |
Other academic advisors | Thomas Jessell |
Marc Trevor Tessier-Lavigne OC FRS FRSC FMedSci (born December 18,1959) is a Canadian-American neuroscientist who was the eleventh president of Stanford University. [1] [2]
Previously,he was a professor at the University of California,San Francisco and then president of Rockefeller University in New York City. He was formerly executive vice president for research and chief scientific officer at Genentech. [3] As of 2021,he is on the boards of directors of Denali Therapeutics and Regeneron Pharmaceuticals,as well as the scientific advisory boards of Denali Therapeutics and Agios Pharmaceuticals. [4] [5] [6]
In 2022,the Stanford board of trustees opened an investigation into allegations that Tessier-Lavigne might have been involved in fabricating results in articles published between 2001 and 2008,when he was working at Genentech. [7] [8] [9] [10] [11] In July 2023,the trustees' report was released,finding that in several papers he co-authored "there was apparent manipulation of research data by others." Tessier-Lavigne then announced that he would be stepping down as president of Stanford,effective August 31,2023. [12] On April 23,2024,it was announced that Tessier-Lavigne would take the role of CEO of a new AI biotech drug discovery startup,Xaira Therapeutics. [13] [14]
Tessier-Lavigne was born in Trenton,Ontario,Canada. He grew up in Europe from ages 7 to 17,where his father was serving with NATO as part of the Canadian Armed Forces. [15] He was the first in his family to attend university. [16]
Tessier-Lavigne received a Bachelor of Science with a major in physics from McGill University in 1980,a Bachelor of Arts with a major in philosophy and physiology from New College,Oxford,in 1982,and a Doctor of Philosophy in physiology from University College London in 1987. [17]
Tessier-Lavigne attended New College,Oxford on a Rhodes Scholarship,where he "first encountered the nervous system and fell in love with it," graduating with first-class honors. [3] [18] [17] His doctoral advisor at University College London was David Attwell. He did postdoctoral research at the MRC Developmental Neurobiology Unit at University College London in 1987 and at the Center for Neurobiology and Behavior at Columbia University with Thomas Jessell from 1987 to 1991. [19] [17]
Tessier-Lavigne started his career at the University of California,San Francisco,from 1991 to 2001. He was a professor of biological sciences at Stanford University from 2001 to 2003. [20] Genentech hired him in 2003 as its senior vice president of Research Drug Discovery. He cited the firm's "potential to create breakthrough therapies for unmet medical needs" as his reason for leaving academia. [3] [21] His research on the development of the brain has uncovered details of how Alzheimer's disease is triggered. [3]
In 2011 Tessier-Lavigne joined Rockefeller University as its 10th president,succeeding Paul Nurse,who returned to Britain to take over as president of the Royal Society. [3] Rockefeller University called Tessier-Lavigne,who supervised a team of 1,400 researchers,the "Board's unanimous first choice for the position". [18] He would be the first high-ranking science employee to leave Genentech following its acquisition by Roche in March 2009. The departure of Tessier-Lavigne from Genentech raised concerns that the company —described by The New York Times as being "among the most innovative and successful biotechnology companies in the world" —would see a negative effect on its scientific culture. Tessier-Lavigne stated that his choice to leave Genentech was unrelated to the Roche merger and that "this is probably the only job that could have lured me away from Genentech." Russell L. Carson,chairman of the board of trustees at Rockefeller University,said that he had "literally called him cold" to offer him the position and that Tessier-Lavigne had the strong scientific background needed to oversee the 70 independent laboratories that operate within the university and whose heads report directly to the president. Richard Scheller,Tessier-Lavigne's superior,called the move "part of the tradition of exchange between academia and Genentech." [3] While it was too early to discuss specific goals,Tessier-Lavigne said that he hoped to work on transforming basic science into treatments for disease. [3]
Tessier-Lavigne is also a member of the Xconomists,an ad hoc team of editorial advisors for the tech news and media company,Xconomy. [22]
On February 4,2016,Stanford University announced that Tessier-Lavigne would become Stanford's 11th president,succeeding John L. Hennessy. [23] As president he presided over the opening of the Stanford Doerr School of Sustainability,the first new school at Stanford since 1948. [24] In November 2020 he was appointed an Officer of the Order of Canada,one of that nation's highest honors,"for his groundbreaking contributions to developmental neuroscience,and his renowned academic leadership and strong advocacy of science." [25]
In November 2022,Stanford announced that its Board of Trustees would oversee an examination of Tessier-Lavigne's publications,"over allegations that neurobiology papers that he co-authored contain multiple manipulated images". Scientific integrity consultant Elisabeth Bik had raised concerns about four papers (in such journals as Science and Nature ) that were co-authored by Tessier-Lavigne,findings which were confirmed by The Stanford Daily . [8] [9] [10] Tessier-Lavigne vehemently denied allegations of any falsification of data,saying "This is a breathtakingly outrageous set of claims that are completely and utterly false." [26] Tessier-Lavigne had notified the journal Science after he was initially informed about the errors in 2015,but the Editor-in-Chief admitted that due to an error they failed to publish the corrections. [27]
On July 19,2023,after the examination report was released,Tessier-Lavigne announced his resignation as president,effective August 31,and the retraction or correction of five scientific papers. [28] While there was no evidence of data manipulation by Tessier-Lavigne directly,the review committee concluded that "in at least four of the five papers,there was apparent manipulation of research data by others." [29] [30] He stated that he chose to step down "for the good of the University" and that the report refuted allegations of fraud and misconduct against him. [12] [31]
Tessier-Lavigne met his wife,Mary Hynes,while he was a postdoctoral fellow at Columbia University. They have three children. [39]
John Leroy Hennessy is an American computer scientist who is chairman of Alphabet Inc. (Google). Hennessy is one of the founders of MIPS Technologies and Atheros,and also the tenth President of Stanford University. Hennessy announced that he would step down in the summer of 2016. He was succeeded as president by Marc Tessier-Lavigne. Marc Andreessen called him "the godfather of Silicon Valley."
The Stanford Daily is the student-run,independent daily newspaper serving Stanford University. The Daily is distributed throughout campus and the surrounding community of Palo Alto,California,United States. It has published since the university was founded in 1892.
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Jonathan David Levin is an American economist and the 13th President of Stanford University. He was previously the 10th Dean of the Stanford Graduate School of Business.
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George D. Yancopoulos is a Greek-American biomedical scientist who is the co-founder,president and chief scientific officer of Regeneron Pharmaceuticals.
Marc D. Hauser is an American evolutionary biologist and a researcher in primate behavior,animal cognition and human behavior and neuroscience. Hauser was a professor of psychology at Harvard University from 1998 to 2011. In 2010 Harvard found him guilty of research misconduct,specifically fabricating and falsifying data,after which he resigned. Because Hauser's research was financed by government grants,the Office of Research Integrity of the Health and Human Services Department also investigated,finding in 2012 that Hauser had fabricated data,manipulated experimental results,and published falsified findings.
Sir John Irving Bell is a Canadian-British immunologist and geneticist. From 2006 to 2011,he was President of the United Kingdom's Academy of Medical Sciences,and since 2002 he has held the Regius Chair of Medicine at the University of Oxford. He was since 2006 Chairman of the Office for Strategic Coordination of Health Research (OSCHR) but in 2020 became a normal member. Bell was selected to the Vaccine Taskforce sometime before 1 July 2020. Bell is also on the board of directors of the SOE quango Genomics England.
Aviv Regev is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member at the Broad Institute of MIT and Harvard and professor at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project,together with Sarah Teichmann.
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Richard H. Scheller is the former chief science officer and head of therapeutics at 23andMe and the former executive vice president of research and early development at Genentech. He was a professor at Stanford University from 1982 to 2001 before joining Genentech. He has been awarded the Alan T. Waterman Award in 1989,the W. Alden Spencer Award in 1993 and the NAS Award in Molecular Biology in 1997,won the 2010 Kavli Prize in Neuroscience with Thomas C. Südhof and James E. Rothman,and won the 2013 Albert Lasker Award for Basic Medical Research with Thomas Südhof. He was also given the Life Sciences Distinguished Alumni Award from University of Wisconsin–Madison. He is a Fellow of the American Academy of Arts and Sciences and a Member of the National Academy of Sciences.
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Theo Baker is an American investigative journalist for The Stanford Daily,the student newspaper of Stanford University. In 2023,he became the youngest recipient of the George Polk Award for his reporting that led to the resignation of Stanford president Marc Tessier-Lavigne.
Richard Paul Saller is an American classicist. He is the former provost of the University of Chicago and the former dean of the School of Humanities and Sciences at Stanford University. He served as president of Stanford from September 2023 to July 2024.