Flonicamid

Flonicamid
Names
	Preferred IUPAC name N-(Cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide
Identifiers
CAS Number	158062-67-0 ;
3D model (JSmol)	Interactive image ;
ChemSpider	8010234 ;
ECHA InfoCard	100.119.736
PubChem CID	9834513 ;
UNII	9500W2Z53J ;
CompTox Dashboard (EPA)	DTXSID8034611 ;
	InChI InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) Key: RLQJEEJISHYWON-UHFFFAOYSA-N;
	SMILES C1=CN=CC(=C1C(F)(F)F)C(=O)NCC#N;
Properties
Chemical formula	C9H6F3N3O
Molar mass	229.162 g/mol
Appearance	White crystalline powder
Odor	none
Density	1.531 at 25 °C
Melting point	157.5 °C (315.5 °F; 430.6 K)
Solubility in water	5.2 g/L at 20 °C
Acidity (pKa)	11.6
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated September 03, 2025

Flonicamid is a pyridine organic compound used as an insecticide against aphids, whiteflies, and thrips.^[1]^[2] It disrupts insect chordotonal organs that can affect hearing, balance, movement to cause cessation of feeding, by inhibiting nicotinamidase.^[3] It is in IRAC group 29.^[4] It is typically sold as wettable granules that are mixed with water before spraying.^[1]

References

1 2 "Flonicamid". sitem.herts.ac.uk. University of Hertfordshire. Retrieved 27 February 2018.
↑ Jeschke, Peter; Witschel, Matthias; Krämer, Wolfgang; Schirmer, Ulrich (25 January 2019). "33.6 Selective Feeding Blockers: Pymetrozine, Flonicamid, and Pyrifluquinazon". Modern Crop Protection Compounds (3rd ed.). Wiley‐VCH. pp. 1501–1526. ISBN 9783527699261.
↑ Qiao, Xiaomu; Zhang, Xiaoyu; Zhou, Zhendong; Guo, Lei (25 November 2022). "An insecticide target in mechanoreceptor neurons". Science Advances. 8 (47): eabq3132. doi:10.1126/sciadv.abq3132. PMC 9683716 . PMID 36417522.{{cite journal}}: CS1 maint: article number as page number (link)
↑ "Modes of Action (MoA) Classification | IRAC". www.irac-online.org. Retrieved 27 February 2018.

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[Hertsfordshire-1] 1 2 "Flonicamid". sitem.herts.ac.uk. University of Hertfordshire. Retrieved 27 February 2018.

[:0-2] Jeschke, Peter; Witschel, Matthias; Krämer, Wolfgang; Schirmer, Ulrich (25 January 2019). "33.6 Selective Feeding Blockers: Pymetrozine, Flonicamid, and Pyrifluquinazon". Modern Crop Protection Compounds (3rd ed.). Wiley‐VCH. pp. 1501–1526. ISBN 9783527699261.

[3] Qiao, Xiaomu; Zhang, Xiaoyu; Zhou, Zhendong; Guo, Lei (25 November 2022). "An insecticide target in mechanoreceptor neurons". Science Advances. 8 (47): eabq3132. doi:10.1126/sciadv.abq3132. PMC 9683716 . PMID 36417522.{{cite journal}}: CS1 maint: article number as page number (link)

[4] "Modes of Action (MoA) Classification | IRAC". www.irac-online.org. Retrieved 27 February 2018.

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Names


Preferred IUPAC name N-(Cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide
Identifiers
CAS Number	158062-67-0 ^Y
3D model (JSmol)	Interactive image
ChemSpider	8010234
ECHA InfoCard	100.119.736
PubChem CID	9834513
UNII	9500W2Z53J ^Y
CompTox Dashboard (EPA)	DTXSID8034611
InChI InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) Key: RLQJEEJISHYWON-UHFFFAOYSA-N
SMILES C1=CN=CC(=C1C(F)(F)F)C(=O)NCC#N
Properties
Chemical formula	C₉H₆F₃N₃O
Molar mass	229.162 g/mol
Appearance	White crystalline powder
Odor	none
Density	1.531 at 25 °C
Melting point	157.5 °C (315.5 °F; 430.6 K)
Solubility in water	5.2 g/L at 20 °C
Acidity (pK_a)	11.6
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references