GFRAL

GFRAL
Identifiers
Aliases	GFRAL , C6orf144, GRAL, UNQ9356, bA360D14.1, GDNF family receptor alpha like
External IDs	OMIM: 617837; MGI: 3607786; HomoloGene: 45748; GeneCards: GFRAL; OMA:GFRAL - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	55,402,493 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	76,120,939 bp
RNA expression pattern
	Top expressed in
	testicle; ; sural nerve; ; right lobe of liver; ; subcutaneous adipose tissue; ; body of pancreas; ; lactiferous gland;
	Top expressed in
	embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	signaling receptor activity ; protein binding ; glial cell-derived neurotrophic factor receptor activity ; receptor tyrosine kinase binding ;
Cellular component	integral component of membrane ; plasma membrane ; intracellular anatomical structure ; membrane ; external side of plasma membrane ; receptor complex ;
Biological process	negative regulation of neuron apoptotic process ; stress-activated protein kinase signaling cascade ; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ; reduction of food intake in response to dietary excess ; glial cell-derived neurotrophic factor receptor signaling pathway ; positive regulation of MAPK cascade ; positive regulation of protein kinase B signaling ; nervous system development ;
	Sources:Amigo / QuickGO
Orthologs
	389400
	404194
	ENSG00000187871
	ENSMUSG00000059383
	Q6UXV0
	Q6SJE0
	NM_207410
	NM_205844
	NP_997293
	NP_995316
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 04, 2024

GDNF family receptor alpha like is a protein that in humans is encoded by the GFRAL gene. ^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000187871 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059383 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: GDNF family receptor alpha like" . Retrieved 2017-09-04.

External links

Overview of all the structural information available in the PDB for UniProt : Q6UXV0 (GDNF family receptor alpha-like) at the PDBe-KB .

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000187871 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059383 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GDNF family receptor alpha like" . Retrieved 2017-09-04.

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GFRAL

Contents

See also

Related Research Articles

References

Further reading

External links