Granuloma gluteale infantum

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Granuloma gluteale infantum
Specialty Dermatology

Granuloma gluteale infantum is a cutaneous condition that appears in the anogenital region of infants as a complication of diaper dermatitis. [1] According to some, no granulomas are found. [2]

Contents

Signs and symptoms

In cases of primary irritant contact dermatitis, the lesions manifest clinically as numerous asymptomatic erythematous papules and nodules in the diaper area. [3]

Causes

Granuloma gluteale infantum is an uncommon dermatosis of infancy with an unknown etiology. [4] Contributing factors include prolonged use of fluorinated steroids, [5] and benzocaine, [6] diaper occlusion in incontinent adults and infants, [7] candidiasis, [8] and irritant contact dermatitis. [9]

Diagnosis

The histological picture shows an underlying hyperplastic epidermis and parakeratosis, accompanied by a non-specific perivascular dermal infiltrate made up of neutrophilshistiocytes, lymphocytesplasma cells, and eosinophils. [10]

Treatment

In order to treat granuloma gluteale infantum, the diaper area needs to be kept dry and clean, and the irritant should be eliminated or lessened. It is recommended to use a barrier cream, such as zinc oxide. [11]

See also

Related Research Articles

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References

  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN   978-1-4160-2999-1.
  2. De Zeeuw R, Van Praag MC, Oranje AP (2000). "Granuloma gluteale infantum: a case report". Pediatr Dermatol. 17 (2): 141–3. doi:10.1046/j.1525-1470.2000.01734.x. hdl: 1765/56610 . PMID   10792807. S2CID   23487761.
  3. Leung, Alexander K. C.; Leong, Kin Fon; Lam, Joseph M. (June 7, 2021). "Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment". Case Reports in Pediatrics. Hindawi Limited. 2021: 1–5. doi: 10.1155/2021/9994067 . ISSN   2090-6811. PMC   8203409 . PMID   34194861.
  4. Konya, Joseph; Gow, Elizabeth (1996). "Granuloma gluteale infantum". Australasian Journal of Dermatology. Wiley. 37 (1): 57–58. doi:10.1111/j.1440-0960.1996.tb00999.x. ISSN   0004-8380. S2CID   29839550.
  5. Pons, S (1976). "[Granuloma gluteale infantum]". Medicina Cutanea Ibero-latino-americana. 4 (5): 359–364. PMID   1035390.
  6. Dytoc, Marlene T.; Fiorillo, Loretta; Liao, Janice; Krol, Alfons L. (June 1, 2002). "Granuloma Gluteale Adultorum Associated with Use of Topical Benzocaine Preparations: Case Report and Literature Review". Journal of Cutaneous Medicine and Surgery: Incorporating Medical and Surgical Dermatology. SAGE Publications. 6 (3): 221–225. doi:10.1007/s10227-001-0042-9. ISSN   1203-4754. PMID   12001002.
  7. Mostafa, Wedad Z.; Abahussein, Abdulaziz A.; Alzayer, Ahmed A. (1992). "Diaper Area Granuloma of Incontinence". The Journal of Dermatology. Wiley. 19 (5): 319–322. doi:10.1111/j.1346-8138.1992.tb03232.x. ISSN   0385-2407. PMID   1644958. S2CID   32495128.
  8. De Zeeuw, Raymond; Van Praag, Marinus C. G.; Oranje, Arnold P. (2000). "Granuloma Gluteale Infantum: A Case Report". Pediatric Dermatology. Wiley. 17 (2): 141–143. doi:10.1046/j.1525-1470.2000.01734.x. ISSN   0736-8046. PMID   10792807. S2CID   23487761.
  9. Walsh, S S; Robson, W J (June 1, 1988). "Granuloma gluteale infantum: an unusual complication of napkin dermatitis". Emergency Medicine Journal. BMJ. 5 (2): 113–115. doi:10.1136/emj.5.2.113. ISSN   1472-0205. PMC   1285498 . PMID   3408529.
  10. Al-Natour, SaharH; Al-Faraidy, NadyaA (2010). "A forgotten complication of diaper dermatitis: Granuloma gluteale infantum". Journal of Family and Community Medicine. Medknow. 17 (2): 107. doi: 10.4103/1319-1683.71994 . ISSN   2230-8229. PMID   21359035.
  11. Ingersoll, Zachary; Garza-Chapa, Juana Irma; Pham, Ryan; Malouf, Peter; Susa, Joseph; Weis, Stephen (August 23, 2018). "Recurrent Granuloma Gluteale Infantum Secondary to Fecal Overflow Incontinence". Case Reports in Dermatology. S. Karger AG. 10 (2): 203–207. doi:10.1159/000492270. ISSN   1662-6567. PMC   6167654 . PMID   30283312.

Further reading