| Irritant contact dermatitis | |
|---|---|
| Specialty | Dermatology  |
Irritant contact dermatitis is a form of contact dermatitis that can be divided into forms caused by chemical irritants and those caused by physical irritants.
| Irritant contact dermatitis | |
|---|---|
| Specialty | Dermatology |
Irritant contact dermatitis is a form of contact dermatitis that can be divided into forms caused by chemical irritants and those caused by physical irritants.
Chemical irritant contact dermatitis is either acute or chronic, which is usually associated with strong and weak irritants respectively. [1] The following definition is provided by Mathias and Maibach (1978): [2] The mechanism of action varies. Detergents, surfactants, extremes of pH, and organic solvents all directly affect the barrier properties of the epidermis. These effects include removing fat emulsion, defatting of dermal lipids, inflicting cellular damage on the epithelium, and increasing the transepidermal water loss by damaging the horny layer water-binding mechanisms and damaging the DNA, which causes the layer to thin. Concentrated irritants have an acute effect, but this is not as common as the accumulative, chronic effect of irritants whose deleterious effects build up with subsequent doses (ESCD 2006).
Chemical irritants are often strong alkalis as found in drain cleaners and soap with lye residues. Many other chemical compounds can also cause contact dermatitis.
Physical irritant contact dermatitis is a less-researched form of irritant contact dermatitis [3] due to its various mechanisms of action and a lack of a test for its diagnosis.
A complete patient history combined with negative allergic patch testing is usually necessary to reach a correct diagnosis. [4] The simplest form of physical irritant contact dermatitis results from prolonged rubbing, although the diversity of implicated irritants is far wider. [5] Examples include paper friction, fiberglass, and scratchy clothing.
Low humidity from air conditioning was found to be the most common cause of physical irritant contact dermatitis. [3] To the lay person a definition of low humidity being a physical irritant can be confusing because low humidity is a deficit (or absence) of an elemental substance, whereas all other irritants implicated in contact dermatitis are in concentrations of relative abundance. So the irritant is actually a lack of water vapour. This confusion is further compounded with the use of the term contact implying 'touching' (as is the case with all other forms of physical irritant contact dermatitis) whereas in the case of low humidity physical irritant contact dermatitis there is an absence of contact with water vapour.
Many plants cause irritant contact dermatitis through their spines or irritant hairs. Some plants such as the buttercup, spurge, and daisy act by chemical means. The sap of these plants contains a number of alkaloids, glycosides, saponins, anthraquinones, and (in the case of plant bulbs) irritant calcium oxalate crystals - all of which can cause crystal irritant contact dermatitis.[ citation needed ]
Butternut squash and Acorn squash have been known to cause an allergic reaction in many individuals, especially in food preparation where the squash skin is cut and exposed to the epidermis.[ citation needed ] Food handlers and kitchen workers often take precautions to wear rubber or latex gloves when peeling butternut and acorn squash to avoid temporary Butternut squash (Cucurbita moschata) dermatitis [6] A contact dermatitis reaction to butternut or acorn squash may result in orange and cracked skin, a sensation of "tightness", "roughness" or "rawness".
A humidifier can be used to prevent low indoor humidity during winter (especially with indoor heating), and dry season.
Cucurbita is a genus of herbaceous fruits in the gourd family, Cucurbitaceae, native to the Andes and Mesoamerica. Five edible species are grown and consumed for their flesh and seeds. They are variously known as squash, pumpkin, or gourd, depending on species, variety, and local parlance. Other kinds of gourd, also called bottle-gourds, are native to Africa and belong to the genus Lagenaria, which is in the same family and subfamily as Cucurbita, but in a different tribe. These other gourds are used as utensils or vessels, and their young fruits are eaten much like those of the Cucurbita species.
Urushiol is an oily mixture of organic compounds with allergenic properties found in plants of the family Anacardiaceae, especially Toxicodendronspp., Comocladia spp. (maidenplums), Metopium spp. (poisonwood), and also in parts of the mango tree as well as the fruit of the cashew tree.
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are not contagious or life-threatening, but can be very uncomfortable.
Calabaza is the generic name in the Spanish language for any type of winter squash. Within an English-language context it specifically refers to the West Indian pumpkin, a winter squash typically grown in the West Indies, tropical America, and the Philippines. Calabaza is the common name for Cucurbita moschata in Cuba, Florida, Puerto Rico, and the Philippines. C. moschata is also known as auyama in Colombia, the Dominican Republic and Venezuela; ayote in Mexico and Central America; zapallo in certain countries of South America; and "pumpkin", "squash", or "calabash" in English-speaking islands.
A moisturizer, or emollient, is a cosmetic preparation used for protecting, moisturizing, and lubricating the skin. These functions are normally performed by sebum produced by healthy skin. The word "emollient" is derived from the Latin verb mollire, to soften.
An occupational disease or industrial disease is any chronic ailment that occurs as a result of work or occupational activity. It is an aspect of occupational safety and health. An occupational disease is typically identified when it is shown that it is more prevalent in a given body of workers than in the general population, or in other worker populations. The first such disease to be recognised, squamous-cell carcinoma of the scrotum, was identified in chimney sweep boys by Sir Percival Pott in 1775. Occupational hazards that are of a traumatic nature are not considered to be occupational diseases.
A patch test is a diagnostic method used to determine which specific substances cause allergic inflammation of a patient's skin.
Butternut squash, known in Australia and New Zealand as butternut pumpkin or gramma, is a type of winter squash that grows on a vine. It has a sweet, nutty taste similar to that of a pumpkin. It has tan-yellow skin and orange fleshy pulp with a compartment of seeds in the blossom end. When ripe, it turns increasingly deep orange, and becomes sweeter and richer. It is a good source of fiber, vitamin C, magnesium, and potassium; and it is a source of vitamin A.
Cocamidopropyl betaine (CAPB) is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine. CAPB is available as a viscous pale yellow solution and it is used as a surfactant in personal care products and animal husbandry. The name reflects that the major part of the molecule, the lauric acid group, is derived from coconut oil. Cocamidopropyl betaine to a significant degree has replaced cocamide DEA.
Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD).
Cucurbita moschata is a species originating in either Central America or northern South America. It includes cultivars known as squash or pumpkin. C. moschata cultivars are generally more tolerant of hot, humid weather than cultivars of C. maxima or C. pepo. They also generally display a greater resistance to disease and insects, especially to the squash vine borer. Commercially made pumpkin pie mix is most often made from varieties of C. moschata. The ancestral species of the genus Cucurbita were present in the Americas before the arrival of humans. No species within the genus is fully genetically isolated from all the other species. C. moschata can be hybridized with all other species. It has been suggested that this shows that the species of Cucurbita have diversified more recently than those of related genera such as Cucumis and Citrullus.
Winter squash is an annual fruit representing several squash species within the genus Cucurbita. Late-growing, less symmetrical, odd-shaped, rough or warty varieties, small to medium in size, but with long-keeping qualities and hard rinds, are usually called winter squash. They differ from summer squash in that they are harvested and eaten in the mature stage when their seeds within have matured fully and their skin has hardened into a tough rind. At this stage, most varieties of this vegetable can be stored for use during the winter. Winter squash is generally cooked before being eaten, and the skin or rind is not usually eaten as it is with summer squash.
Eyelid dermatitis is commonly related to atopic dermatitis or allergic contact dermatitis. Volatile substances, tosylamide, epoxy hardeners, insect sprays, and lemon peel oil may be implicated, with many cases of eyelid contact dermatitis being caused by substances transferred by the hands to the eyelids.
A barrier cream is a topical formulation used in industrial applications and as a cosmetic to place a physical barrier between the skin and contaminants that may irritate the skin. There are many other terms for creams designed to protect skin from harmful substances, including skin protective creams, pre-work creams, antisolvent gels, protective ointments, and shielding lotions. Three classes of barrier creams are used: water repellent creams, water-soluble creams, and creams designed for special applications. Barrier creams may contain substances such as zinc oxide, talc or kaolin to layer over the skin. For hand care they are designed to protect against the harm from detergents and other irritants.
Defatting is the chemical dissolving of dermal lipids, from the skin, on contact with defatting agents. This can result in water loss from the affected area and cause the whitening and drying of the skin which may result in cracking, secondary infection and chemical irritant contact dermatitis.
Garlic allergy or allergic contact dermatitis to garlic is a common inflammatory skin condition caused by contact with garlic oil or dust. It mostly affects people who cut and handle fresh garlic, such as chefs, and presents on the tips of the thumb, index and middle fingers of the non-dominant hand. The affected fingertips show an asymmetrical pattern of fissure as well as thickening and shedding of the outer skin layers, which may progress to second- or third-degree burn of injured skin.
Occupational skin diseases are ranked among the top five occupational diseases in many countries.
Nickel allergy is any of several allergic conditions provoked by exposure to the chemical element nickel. Nickel allergy often takes the form of nickel allergic contact dermatitis (Ni-ACD), a form of allergic contact dermatitis (ACD). Ni-ACD typically causes a rash that is red and itchy and that may be bumpy or scaly. The main treatment for it is avoiding contact with nickel-releasing metals, such as inexpensive jewelry. Another form of nickel allergy is a systemic form: systemic nickel allergy syndrome (SNAS) can mimic some of the symptoms of irritable bowel syndrome (IBS) and also has a dermatologic component.
Lip licker's dermatitis is a type of skin inflammation around the lips due to damage by saliva from repetitive lip licking and is classified as a subtype of irritant contact cheilitis. The resulting scaling, redness, chapping, and crusting makes a well-defined ring around the lips. The rash may extend as far as the tongue can reach and usually does not occur at the corners of the mouth. It commonly occurs during winter months but some people can have it year-round if lip licking is a chronic habit.
Honeynut squash is an interspecific hybrid winter squash cultivar bred from butternut and buttercup squash. It has dark tan to orange skin with orange fleshy pulp. When ripe, it turns from green to a deep orange and becomes sweeter and richer. Honeynut squash has a similar shape and flavor to butternut squash but averages about half the size and is sweeter. It has two to three times more beta-carotene than butternut squash. Honeynut squash can be roasted, sautéed, puréed, added to soups, stews, and braises, and has enough sugar content for desserts.