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| Names | |
|---|---|
| Preferred IUPAC name 5-Methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzene-1,3-diol | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider | |
PubChem CID | |
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| Properties | |
| C22H32O2 | |
| Molar mass | 328.496 g·mol−1 |
| Melting point | 41 °C (106 °F; 314 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Grifolin is an isolate of the mushroom Albatrellus confluens which upregulates DAPK1 in vitro . [1]
Luo Ben, better known by his courtesy name Guanzhong, was a Chinese writer who lived during the Ming Dynasty. He was also known by his pseudonym Huhai Sanren. Luo was attributed with writing Romance of the Three Kingdoms and editing Water Margin, the first two of the Four Great Classical Novels of Chinese literature.
CP 55,940 is a synthetic cannabinoid which mimics the effects of naturally occurring THC. CP 55,940 was created by Pfizer in 1974 but was never marketed. It is currently used to study the endocannabinoid system.
Luo Xuejuan is a female Chinese swimmer, who competed mostly in the breaststroke. She is a former world record holder in the 50-meter breastroke.
In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. The complementary process that involves increases of such components is called upregulation.
The dozen Luo, Lwo or Lwoian languages are spoken by the Luo peoples in an area ranging from southern Sudan to southern Kenya, with Dholuo extending into northern Tanzania and Alur into the Democratic Republic of the Congo. They form one of the two branches of the Western Nilotic family, the other being the Dinka–Nuer. The Southern Luo varieties are mutually intelligible, and apart from ethnic identity they might be considered a single language.
The Luo of Kenya and Tanzania are a Nilotic ethnic group native to western Kenya and the Mara Region of northern Tanzania in East Africa. The Luo are the fourth-largest ethnic group (10.65%) in Kenya, after the Kikuyu (17.13%), the Luhya (14.35%) and the Kalenjin (13.37%). The Tanzanian Luo population was estimated at 1.1 million in 2001 and 1.9 million in 2010. They are part of a larger group of related Luo peoples who inhabit an area ranging from South Sudan, southwestern Ethiopia, northern and eastern Uganda, northeastern Congo-Kinshasa, southwestern Kenya and northern Tanzania.
The Dholuo dialect or Nilotic Kavirondo, is a dialect of the Luo group of Nilotic languages, spoken by about 4.2 million Luo people of Kenya and Tanzania, who occupy parts of the eastern shore of Lake Victoria and areas to the south. It is used for broadcasts on KBC.
Ataxin 7 (ATXN7) is a protein of the SCA7 gene, which contains 892 amino acids with an expandable poly(Q) region close to the N-terminus. The expandable poly(Q) motif region in the protein contributes crucially to spinocerebellar ataxia (SCA) pathogenesis by the induction of intranuclear inclusion bodies. ATXN7 is associated with both olivopontocerebellar atrophy type 3 (OPCA3) and spinocerebellar ataxia type 7 (SCA7).
Leukotriene C4 (LTC4) is a leukotriene. LTC4 has been extensively studied in the context of allergy and asthma. In cells of myeloid origin such as mast cells, its biosynthesis is orchestrated by translocation to the nuclear envelope along with co-localization of cytosolic phospholipase A2 (cPLA2), Arachidonate 5-lipoxygenase (5-LO), 5-lipoxygenase-activating protein (FLAP) and LTC4 synthase (LTC4S), which couples glutathione to an LTA4 intermediate. The MRP1 transporter then secretes cytosolic LTC4 and cell surface proteases further metabolize it by sequential cleavage of the γ-glutamyl and glycine residues off its glutathione segment, generating the more stable products LTD4 and LTE4. All three leukotrienes then bind at different affinities to two G-protein coupled receptors: CYSLTR1 and CYSLTR2, triggering pulmonary vasoconstriction and bronchoconstriction.
Death-associated protein kinase 1 is an enzyme that in humans is encoded by the DAPK1 gene.
Death-associated protein kinase 3 is an enzyme that in humans is encoded by the DAPK3 gene.
Metastasis-associated protein MTA3 is a protein that in humans is encoded by the MTA3 gene. MTA3 protein localizes in the nucleus as well as in other cellular compartments MTA3 is a component of the nucleosome remodeling and deacetylate (NuRD) complex and participates in gene expression. The expression pattern of MTA3 is opposite to that of MTA1 and MTA2 during mammary gland tumorigenesis. However, MTA3 is also overexpressed in a variety of human cancers.
Death-associated protein kinase 2 is an enzyme that in humans is encoded by the DAPK2 gene.
Trechnotheria is a group of mammals that includes the therians and some fossil mammals from the Mesozoic Era. In the Jurassic through Cretaceous periods, the group was endemic to what would be Asia and Africa.
G protein-coupled receptor 137B also known as GPR137B is a G protein-coupled receptor which in humans is encoded by the GPR137B gene. The expression of GPR137B is upregulated during kidney development.
In molecular biology, mir-433 is a short non-coding RNA molecule. MicroRNAs (miRNAs) function as posttranscriptional regulators of expression levels of other genes by several mechanisms. They play roles in development, metabolism and carcinogenesis.
Southern Luo is a dialect cluster of Uganda and neighboring countries. Although Southern Luo dialects are mutually intelligible, there are six ethnically and culturally distinct varieties which are considered to be separate languages socially.
Luodao or Luoism (罗教), originally Wuweiism (无为教), refers to a Chinese folk religious tradition, a wide range of sect organisations flourishing over the last five hundred years, which trace their origins back to the mystic and preacher Luo Menghong (1443-1527), the Patriarch Luo and the revelation contained in his major scripture, the Wǔbùliùcè, which official title is The Scroll of Apprehending the Way through Hard Work and that marked the beginning of the precious scrolls' tradition.
The Luo alphabet was invented by Kefa Ombewa and Paul Sidandi between 2009 and 2012 to write Luo languages, specifically Dholuo of Kenya, in a unique way. The script is a left-to-right alphabet, with 33 letters connected to each other by a line running along the bottom.
The Legend of Luo Xiaohei (罗小黑战记) is a flash animation and webtoon developed by Chinese artist MTJJ. It derives from an animated series that was mainly broadcast online in March 2011. The franchise has also been extended to become a social media sticker series on WeChat. As of August 28, 2019, 28 episodes of "The Legend of Luo Xiaohei" are available alongside 3 extra videos, "Exam Day", "Sh…", and "Goodnight Meow". A feature-length prequel film named "The Legend of Hei" was released in Chinese and Japanese theaters in September, 2019.
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