A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic organic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of organic heterocycles.
Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH2)4NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most organic solvents. It has a characteristic odor that has been described as "ammoniacal, fishy, shellfish-like". In addition to pyrrolidine itself, many substituted pyrrolidines are known.
Pyrazole is an organic compound of azole group with the formula C3H3N2H. It is a heterocycle characterized by a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms, which are in ortho-substitution. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugate acid 2.49 at 25 °C). Pyrazoles are also a class of compounds that have the ring C3N2 with adjacent nitrogen atoms. Notable drugs containing a pyrazole ring are celecoxib (celebrex) and the anabolic steroid stanozolol.
Pyridazine is an aromatic, heterocyclic, organic compound with the molecular formula C4H4N2. It contains a six-membered ring with two adjacent nitrogen atoms. It is a colorless liquid with a boiling point of 208 °C. It is isomeric with two other diazine rings, pyrimidine and pyrazine.
Charles Wayne Rees CBE FRS FRSC was a British organic chemist.
Kojic acid is an organic compound with the formula HOCH2C5H2O2OH. It is a derivative of 4-pyrone that functions in nature as a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji. Kojic acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine. It is a mild inhibitor of the formation of pigment in plant and animal tissues, and is used in food and cosmetics to preserve or change colors of substances. It forms a bright red complex with ferric ions.
Abbas Shafiee was an Iranian pharmaceutical chemist. He was the president of faculty of pharmacy at Tehran University. He published more than 350 scientific articles in peer-reviewed international journals.
Heterocycles may refer to:
Coumestan is a heterocyclic organic compound. Coumestan forms the central core of a variety of natural compounds known collectively as coumestans. Coumestans are oxidation products of pterocarpan that are similar to coumarin. Coumestans, including coumestrol, a phytoestrogen, are found in a variety of plants. Food sources high in coumestans include split peas, pinto beans, lima beans, and especially alfalfa and clover sprouts.
1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colourless liquid that is used as a specialty solvent, a base, and as a precursor to some ionic liquids. It is a fundamental nitrogen heterocycle and as such mimics for various nucleoside bases as well as histidine and histamine.
IMes is an abbreviation for an organic compound that is a common ligand in organometallic chemistry. It is an N-heterocyclic carbene (NHC). The compound, a white solid, is often not isolated but instead is generated upon attachment to the metal centre.
ZooKeys is a peer-reviewed open access scientific journal covering zoological taxonomy, phylogeny, and biogeography. It was established in 2008 and the founding editor-in-chief was Terry Erwin until his death in 2020. In December 2023, Torsten Dikow was appointed the new editor-in-chief. It is published by Pensoft Publishers.
The Barton–Zard reaction is a route to pyrrole derivatives via the reaction of a nitroalkene with an α-isocyanide under basic conditions. It is named after Derek Barton and Samir Zard who first reported it in 1985.
Journal of Heterocyclic Chemistry is a peer-reviewed scientific journal summarizing progress in the field of heterocycle chemistry. It is a source for the ChemSpider database.
Thianthrene is a sulfur-containing heterocyclic chemical compound. It is a derivative of the parent heterocycle called dithiin. It is notable for its ease of oxidation.
The Minisci reaction is a named reaction in organic chemistry. It is a nucleophilic radical substitution to an electron deficient aromatic compound, most commonly the introduction of an alkyl group to a nitrogen containing heterocycle. The reaction was published in 1971 by F. Minisci. In the case of N-Heterocycles, the conditions must be acidic to ensure protonation of said heterocycle. A typical reaction is that between pyridine and pivalic acid with silver nitrate, sulfuric acid and ammonium persulfate to form 2-tert-butylpyridine. The reaction resembles Friedel-Crafts alkylation but with opposite reactivity and selectivity.
PeerJ is an open access peer-reviewed scientific mega journal covering research in the biological and medical sciences. It officially launched in June 2012, started accepting submissions on December 3, 2012, and published its first articles on February 12, 2013.
José Elguero Bertolini is a Spanish chemist best known for his contributions to heterocyclic chemistry. He is Honorary Research Professor at the Medicinal Chemistry Institute of the Spanish Council for Scientific Research (CSIC).
The Charles Rees Award is granted by the Royal Society of Chemistry to "reward excellence in the field of heterocyclic chemistry". It was established in 2008 and is awarded biennially. The winner receives £2000, a medal and a certificate, and delivers a lecture at the Lakeland Symposium, Grasmere, UK. Winners are chosen by the Heterocyclic and Synthesis Group, overseen by the Organic Division Awards Committee.
Alfred Hassner was an Israeli organic chemist.
