Jan Poleszczuk

Last updated
Jan Poleszczuk
Born (1986-10-19) October 19, 1986 (age 38)
Poland
Alma mater
AwardsLaureate of the POLITYKA Scientific Awards(2017) [1]
Scientific career
Fields Mathematics, biocybernetics and biomedical engineering
InstitutionsInstitute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Maria Sklodowska-Curie National Research Institute of Oncology
Thesis
  • "Exploring potential tumor growth modulating mechanisms in cells having different status of TP53 gene"(PhD in Mathematics) 17 December 2015
  • "Mathematical modeling of cancer cell response to therapy induced stress" (Ph.D. in Biocybernetics and Biomedical Engineering) February 2014
 (2014, 2015)
Doctoral advisor Maria Wideł and Urszula Alicja Foryś
Website www.jpoleszczuk.pl

Jan Poleszczuk (born 19 October 1986) is a Polish mathematician and biologist known for his contributions in mathematical biology. [2] [3]

Contents

Early life and education

Poleszczuk was born on 19 October 1986. [4] In June 2010, he graduated from Warsaw University's Faculty of Mathematics, Informatics and Mechanics with a Master of Science in mathematical methods in biology and social sciences based on the thesis "Modeling of tumor angiogenesis and antiangiogenic therapy on the basis of Hahnfeldt et al. mode".

Academic career

Under supervision of Maria Wideł and coadvisor Urszula Alicja Foryś, [5] [6] Jan Poleszczuk defended the Ph.D. in Biocybernetics and Biomedical Engineering at Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, based on dissertation: "Mathematical modeling of cancer cell response to therapy induced stress" [7] February 2014, Next, under supervision of Urszula Alicja Foryś with coadvisor Maria Wideł, he defended the Ph.D. in Mathematics at Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, based on thesis ""Exploring potential tumor growth modulating mechanisms in cells having different status of TP53 gene"" [8] [9] in December 2015.

Since February 2012, he has been a research fellow at the Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. [10]

On 2020-06-26, his dissertation Mathematical modeling in the study of evolution and treatment of cancer with radio and immunotherapy was presented to the scientific council of the Maciej Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. He was habilitated in the field of engineering sciences, discipline of biomedical engineering, receiving the degree of doctor of science.

Contributions

His publications are listed in various data bases. [11] The author and co-author of more than 60 scientific articles. [12] [13] [2] Most of the works are interdisciplinary. The most cited works are in the area of mathematical modeling of gene expression Stochastic models of gene expression with delayed degradation, [14] immune reaction Mathematical modelling of immune reaction against gliomas: sensitivity analysis and influence of delays. [15]

As a mathematician working in the field of oncology, he supports biologists, medical doctors, physicists and chemists. [16] His aim is to understand how gene mutations interact and how they affect cancer growth. His work is focused on increasing the effectiveness of existing therapies (radiotherapy and chemotherapy), which may improve the situation of many more patients more quickly than with new targeted drug therapies with limited effects. In radiotherapy, he created a model aimed at selecting, from among many metastases, this tumor in the patient's body, the irradiation of which will maximize the overall effectiveness of the therapy. He also used mathematical and computer methods to calculate and propose radiation therapy plans to harm the cancer as much as possible but preserve healthy tissues and organs. He is currently working on improving the dosage of chemotherapy so that it does not result in tumor resistance to treatment in relapses. [17] He is member of Polish Mathematical Society (Treasurer for years 2017–2020), [18] Polish Radiation Research Society, Society for Mathematical Biology [19] and American Association for Cancer Research. [20]

References

  1. ↑ "Laureate of the "POLITYKA" Scientific Awards 2017" . Retrieved September 20, 2020.
  2. 1 2 US US9990715B2,Heiko Enderling&Kimberly A. Luddy and Eduardo G. Moros,"Radiotherapy targeted to promote a systemic abscopal effect",published June 5, 2018, assigned to H Lee Moffitt Cancer Center and Research Institute Inc
  3. ↑ "Jan Poleszczuk ResearchGate" . Retrieved 2020-12-30.
  4. ↑ Foryś, Urszula (2012). "Jan Poleszczuk – the Winner of the Polish Mathematical Society's Prize". Mathematica Applicanda . 40 (2012): 127–130. doi:10.14708/ma.v40i1.289. ISSN   2299-4009.
  5. ↑ "Urszula Alicja Foryś in Genealogy Project" . Retrieved September 20, 2020.]
  6. ↑ "Urszula Alicja Foryś". Nowa Nauka Polska (in Polish). National Information Processing Institute. Retrieved 20 December 2020.
  7. ↑ "Scientific degrees and titles at the Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology". Archived from the original on February 25, 2014. Retrieved September 20, 2020.
  8. ↑ Jan Poleszczuk at the Mathematics Genealogy Project
  9. ↑ "Ludzie Nauki". ludzie.nauka.gov.pl. Retrieved 2025-01-23.
  10. ↑ Poleszczuk, Jan. "Nowa Nauka Polska" (in Polish). National Information Processing Institute. Retrieved 20 September 2020.
  11. ↑ Poleszczuk, Jan. "ORCID". orcid.org. Retrieved 2025-01-23.
  12. ↑ "Jan Poleszczuk papers in Mathematical Reviews". MathSciNet . American Mathematical Society . Retrieved 2020-02-03.
  13. ↑ "Jan Poleszczuk papers". Zentralblatt MATH . Springer Science+Business Media . Retrieved 2019-03-13.
  14. ↑ Miȩkisz, Jacek; Poleszczuk, Jan; Bodnar, Marek; Foryś, Urszula (2011-09-01). "Stochastic Models of Gene Expression with Delayed Degradation". Bulletin of Mathematical Biology. 73 (9): 2231–2247. doi: 10.1007/s11538-010-9622-4 . ISSN   1522-9602. PMID   21210242.
  15. ↑ Piotrowska, Monika Joanna; Bodnar, Marek; Poleszczuk, Jan; Foryś, Urszula (2013-06-01). "Mathematical modelling of immune reaction against gliomas: Sensitivity analysis and influence of delays". Nonlinear Analysis: Real World Applications. 14 (3): 1601–1620. doi:10.1016/j.nonrwa.2012.10.020. ISSN   1468-1218.
  16. ↑ Poleszczuk, Jan (2025), Profile on Linkedin , retrieved 2025-01-20
  17. ↑ "Jan Poleszczuk in MedLine". National Center for Biotechnology Information . National Library of Medicine . Retrieved 2020-12-30.
  18. ↑ "Jan Poleszczuk in PTM". Polish Mathematical Society . Retrieved 2020-12-30.
  19. ↑ "About Me – Jan Poleszczuk, Ph.D." Retrieved 2025-01-23.
  20. ↑ "Jan Poleszczuk - Akademia Młodych Uczonych". Akademia Młodych Uczonych. Archived from the original on 2022-07-24. Retrieved 2025-01-23.
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