Jan van Hest

Last updated
Jan van Hest
Born (1968-09-27) 27 September 1968 (age 54)
Tilburg, The Netherlands
NationalityDutch
Alma mater Eindhoven University of Technology
Known for Polymersomes, Artificial cells and organelles, Nanomedicine, Self-assembly
Awards2020 Spinoza Prize
Scientific career
Fields Organic Chemistry
Polymer Chemistry
Materials Science
Nanotechnology
Institutions Eindhoven University of Technology, 2016–present
Radboud University Nijmegen, 2000-present
DSM Research, 1997-2000
Thesis New molecular architectures based on dendrimers  (1996)
Doctoral advisor Bert Meijer, Roeland Nolte
Website https://www.tue.nl/en/research/researchers/jan-van-hest/

Jan Cornelis Maria van Hest (born 28 September 1968) is a Dutch scientist of organic chemistry, best known for his research regarding polymersomes and nanoreactors. He currently holds the position of professor of bioorganic chemistry at Eindhoven University of Technology and is scientific director at the Institute of Complex Molecular Systems. Among the awards he has received, he was one of the recipients of the 2020 Spinoza Prize. [1]

Contents

Biography

Van Hest received his MSc degree in Chemical Engineering with distinction from the Eindhoven University of Technology in 1991. He subsequently obtained his PhD in macro-organic chemistry from the same university in 1996 under the supervision of Bert Meijer. [2] His doctoral thesis 'New molecular architectures based on dendrimers' was awarded the DSM Science and Technology award and the SNS Bank Prijs for best thesis in fundamental engineering sciences. In 1996, van Hest received a NWO Talent stipend for a post-doc position on polypeptide engineering at University of Massachusetts Amherst where he collaborated with professor David Tirrell. He returned to the Netherlands to work at DSM Research in 1997 as researcher and later as group leader. Van Hest was appointed as full professor to set up a group in bioorganic chemistry at Radboud University Nijmegen in 2000. His early career focused on developing self-assembling biohybrid block copolymers. [3] In 2010 he was awarded a VICI grant for research on artificial organelles, [4] and in 2016 he obtained an ERC Advanced grant on artificial endosymbiosis. [5] Van Hest moved to Eindhoven University of Technology in 2016, to chair the bioorganic chemistry group at the departments of Chemical Engineering and Biomedical Technology. [6] He was appointed scientific director of the Institute for Complex Molecular Systems (ICMS) at Eindhoven University of Technology in 2018. [7]

To date, van Hest has published over 250 peer reviewed scientific articles, cited more than 15,000 times and has an h-index of 57. [8]

Honors and awards

Van Hest was elected member of the Royal Netherlands Academy of Arts and Sciences in 2019. [9] He was member of The Young Academy of the Royal Netherlands Academy of Arts and Sciences from 2005 to 2011. Additionally, van Hest is an elected Fellow of the Royal Society of Chemistry (FRSC), a visiting fellow of the Chinese Academy of Science, a member of the American Chemical Society, the American Association for the Advancement of Science and the Royal Netherlands Chemical Society.

Listed are some of the prizes awarded to van Hest:

Professional activities

Van Hest served as vice-dean at the Faculty of Science in Nijmegen from 2006 to 2010. [12] He is chairman at the Dutch national postgraduate research school Polymer Technology Netherlands. [13] Van Hest serves as associate editor of Bioconjugate Chemistry. [14] He is furthermore an advisory board member of Macromolecular Bioscience, [15] Journal of Materials Chemistry, [16] and Chemical Science. [17]

Van Hest is a co-founder of the companies, Noviotech, Encapson and Future Chemistry and serves on the scientific board at GATT Tech, [18] Euronol Chemical Technology Center.

Related Research Articles

<span class="mw-page-title-main">Ewine van Dishoeck</span> Dutch astronomer and chemist

Ewine Fleur van Dishoeck is a Dutch astronomer and chemist. She is Professor of Molecular Astrophysics at Leiden Observatory, and served as the President of the International Astronomical Union (2018–2021) and a co-editor of the Annual Review of Astronomy and Astrophysics (2012–present). She is one of the pioneers of astrochemistry, and her research is aimed at determination of the structure of cosmic objects using their molecular spectra.

<span class="mw-page-title-main">Spinoza Prize</span> Dutch scientific award

The Spinoza Prize is an annual award of 2.5 million euro prize money, to be spent on new research given by the Dutch Research Council (NWO). The award is the highest scientific award in the Netherlands. It is named after the philosopher Baruch de Spinoza.

<span class="mw-page-title-main">Bert Meijer</span> Dutch organic chemist

Egbert (Bert) Willem Meijer is a Dutch organic chemist, known for his work in the fields of supramolecular chemistry, materials chemistry and polymer chemistry. Meijer, who is distinguished professor of Molecular Sciences at Eindhoven University of Technology (TU/e) and Academy Professor of the Royal Netherlands Academy of Arts and Sciences, is considered one of the founders of the field of supramolecular polymer chemistry. Meijer is a prolific author, sought-after academic lecturer and recipient of multiple awards in the fields of organic and polymer chemistry.

<span class="mw-page-title-main">Piet Gros</span> Dutch chemist (born 1962)

Piet Gros is a Dutch chemist and professor biomacromolecular crystallography at Utrecht University. In 2010 he received the NWO Spinoza Prize for the elucidation of the three-dimensional structure of the C3 protein, which plays a central role in the complement system and contributes to innate immunity.

The Bijvoet Centre for Biomolecular Research is a research institute at Utrecht University. The Bijvoet Centre performs research on the relation between the structure and function of biomolecules, including proteins and lipids, which play a role in biological processes such as regulation, interaction and recognition. The Bijvoet Centre houses advanced infrastructures for the analysis of proteins and other biomolecules using NMR, X-ray crystallography, electron microscopy and mass spectrometry. The institute is named after famous Dutch chemist Johannes Martin Bijvoet, who worked at Utrecht University.

<span class="mw-page-title-main">Albert van den Berg (physicist)</span> Dutch physicist

Albert van den Berg is a Dutch physicist who works on nanotechnology-miniaturization in physics, chemistry, biology and biotechnology.

<span class="mw-page-title-main">René Janssen</span>

René A.J. Janssen is a Dutch University Professor of the Moleculair Materials and Nanosystems group within the department of Chemical engineering and Chemistry at Eindhoven University of Technology.

<span class="mw-page-title-main">Bert Weckhuysen</span> Belgian chemist

Bert Marc Weckhuysen FRSC is a professor of inorganic chemistry and catalysis at Utrecht University, originally from Belgian descent. Weckhuysen is best known for his developments in operando (micro)spectroscopy; imaging catalysis at macro, meso and micro scales, from the reactor down to interactions between single atoms and molecules. He was a winner of the 2013 Spinoza Prize, and was knighted in the Order of the Netherlands Lion in 2015.

<span class="mw-page-title-main">Mike Jetten</span>

Mike Jetten is a Dutch professor of Microbiology at the Radboud University Nijmegen. He was a winner of the 2012 Spinoza Prize.

<span class="mw-page-title-main">Anna Akhmanova</span> Russian cell biologist

Anna Sergeevna Akhmanova is a Russian-born professor of Cell Biology at Utrecht University in the Netherlands. She is best known for her research regarding microtubules and the proteins, called TIPs, that stabilize one specific end of the tubules. Among the awards she has won, she was one of the recipients of the 2018 Spinoza Prize, the highest honor for Dutch scientists.

<span class="mw-page-title-main">Theo Rasing</span>

Theodorus "Theo" Henricus Maria Rasing is a Dutch professor of experimental physics at Radboud University Nijmegen. His expertise lies in the field of magneto-optics. He was a winner of the 2008 Spinoza Prize.

<span class="mw-page-title-main">Bas van Bavel</span> Dutch historian

Balthassar Jozef Paul "Bas" van Bavel is a Dutch historian. He has held the chair of Transitions of Economy and Society at Utrecht University since 2011, and has been professor of Economic and Social History since 2007. His research has mostly focused on pre-industrial Northwestern Europe. He was one of the winners of the 2019 Spinoza Prize, the highest award in Dutch science.

<span class="mw-page-title-main">Marileen Dogterom</span> Dutch biophysicist

Marileen Dogterom is a Dutch biophysicist and professor at the Kavli Institute of Nanoscience at Delft University of Technology. She published in Science, Cell, and Nature and is notable for her research of the cell cytoskeleton. For this research, she was awarded the 2018 Spinoza Prize.

<span class="mw-page-title-main">Sijbren Otto</span>

Sybren Otto is Professor of Systems chemistry at the Stratingh Institute for Chemistry, University of Groningen.

<span class="mw-page-title-main">Mihai Netea</span>

Mihai G. Netea is a Romanian Dutch physician and professor at Radboud University Nijmegen, specialized in infectious disease, immunology, and global health.

<span class="mw-page-title-main">Roeland Nolte</span> Dutch chemist, emeritus Royal Netherlands of Arts and Sciences professor

Roeland J. M. Nolte is a Dutch chemist, known for his work in the fields of organic chemistry, biochemistry, polymer chemistry, and supramolecular chemistry. He is an emeritus Royal Netherlands of Arts and Sciences professor and an emeritus professor of Organic Chemistry at Radboud University in Nijmegen, The Netherlands. Currently, he holds a special chair, i.e. professor of Molecular Nanotechnology, at this university. Nolte is considered to be one of the pioneers of the field of supramolecular chemistry, which encompasses the design and synthesis of new chemical structures from low molecular weight compounds and biopolymers using so-called non-covalent interactions. He published many studies on supramolecular assembly and biomimetic catalysts, which find applications in the field of nanomaterials and medicine.

<span class="mw-page-title-main">Katja Loos</span> Dutch polymer chemist (born 1971)

Katja Loos is professor at the Zernike Institute for Advanced Materials of the University of Groningen, The Netherlands holding the chair of Macromolecular Chemistry and New Polymeric Materials.

<span class="mw-page-title-main">Emiel J.M. Hensen</span>

Emiel Jan Maria Hensen is a Dutch chemist and professor of Inorganic Materials and Catalysis at Eindhoven University of Technology. Hensen's research has focused on developing novel heterogeneous catalysts, kinetics and mechanism, and energy conversion. He leads a team of over 50 researchers working to improve "clean and sustainable chemical conversion processes for the production of fuels and chemicals."

<span class="mw-page-title-main">Jan Hoeijmakers</span> Dutch biologist, biochemist and geneticist

Jan Hendrik Jozef Hoeijmakers is a Dutch molecular biologist, biochemist, and molecular geneticist.

Reuven Agami is a Dutch cancer researcher. He is a professor of Oncogenomics at Erasmus University Rotterdam and head of the section of Oncogenomics at the Netherlands Cancer Institute-Antoni van Leeuwenhoekziekenhuis.

References

  1. "Spinoza Laureate Prof. Jan van Hest". www.nwo.nl/en. Retrieved 2020-06-20.
  2. van Hest, Jan Cornelis Maria (1996). "New molecular architectures based on dendrimers" (PDF).{{cite journal}}: Cite journal requires |journal= (help)
  3. Ayres, L.; Adams, H.P.; Löwik, D.W.P.M.; Hest, J.C.M. van (2005-10-31). "Peptide–polymer vesicles prepared by atom transfer radical polymerization". J. Polym. Sci. A Polym. Chem. 43 (24): 6355–6366. Bibcode:2005JPoSA..43.6355A. doi:10.1002/pola.21107. S2CID   20067098.
  4. "Vici awards 2010" . Retrieved 2020-06-20.
  5. "ERC Advanced Grants for Jan van Hest and John van Opstal/" . Retrieved 2020-06-20.
  6. "TU/e appoints Jan van Hest as head of new research group" . Retrieved 2020-06-20.
  7. "Jan van Hest named the new scientific director of ICMS" . Retrieved 2020-06-20.
  8. "Personal profile Jan C.M. van Hest on TU/e website" . Retrieved 2020-06-20.
  9. "Jan van Hest". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 25 June 2020.
  10. "Radboud Education Awards" . Retrieved 2020-06-20.
  11. "Professor Jan C.M. van Hest" . Retrieved 2020-06-20.
  12. "Nieuwe vicedecaan" (in Dutch). Retrieved 2020-06-20.
  13. "Board of the National Dutch Research School PTN". 24 May 2019. Retrieved 2020-06-20.
  14. "Bioconjugate Chemistry Editorial Board" . Retrieved 2020-06-20.
  15. "Macromolecular Bioscience Editorial Board" . Retrieved 2020-06-20.
  16. "Journal of Materials Chemistry Editorial Board" . Retrieved 2020-06-20.
  17. "Chemical Science Editorial Board" . Retrieved 2020-06-20.
  18. "GATT Tech Scientific board" . Retrieved 2020-06-20.