Jennifer Webster-Cyriaque

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Jennifer Webster-Cyriaque
Jennifer Webster-Cyriaque.jpg
Webster-Cyriaque in 2020
Alma mater University at Buffalo
University of North Carolina at Chapel Hill
Scientific career
FieldsOral microbiome, immunology, HIV
Institutions University of North Carolina
National Institute of Dental and Craniofacial Research
Thesis The role of Epstein-Barr virus in hairy leukoplakia and other AIDS associated oral mucosal lesions  (1998)
Doctoral advisor Nancy Raab-Traub

Jennifer Y. Webster-Cyriaque is an American dentist and immunologist specializing in the oral microbiome, salivary gland disease in patients with HIV, and cancer-causing viruses. She became the deputy director of the National Institute of Dental and Craniofacial Research in November 2020. Webster-Cyriaque was a faculty member at UNC Adams School of Dentistry and the UNC School of Medicine for 21 years.

Contents

Education

Webster-Cyriaque completed a B.A. in biology and social science in 1988 and a D.D.S. from University at Buffalo in 1992. She earned a doctorate in microbiology and immunology from the University of North Carolina at Chapel Hill (UNC) in 1998. [1] Her dissertation was titled The role of Epstein–Barr virus in hairy leukoplakia and other AIDS associated oral mucosal lesions. Nancy Raab-Traub  [ Wikidata ] was her doctoral advisor. [2]

Career

Webster-Cyriaque has been part of the UNC Adams School of Dentistry's and the UNC School of Medicine's faculty for over twenty years. [3] Webster-Cyriaque is one of the UNC's tenured full professors. She supported the UNC Hospital’s dental clinic and she investigated a potential cause for a salivary gland disease in HIV patients. She assessed the oral microbiome's implications for Oncoviruses, and its impact on the HIV patient's oral health. [1]

The "UNC Malawi project" is based at Kamuzu Central Hospital Kamuzu Central Hospital.jpg
The "UNC Malawi project" is based at Kamuzu Central Hospital

In 2004, she became responsible for the "UNC Malawi project". [3] The project is a partnership between the Malawi Ministry of Health (led by Khumbize Chiponda since 2020) and the UNC. [4] The UNC Malawi Project is based in the country's capital at the Kamuzu Central Hospital. [5] Webster-Cyriaque assisted in creating Malawi’s first dental school in 2019. [3] Webster-Cyriaque was the chair/vice chair of the Oral HIV/AIDS Research Alliance, the research director at the National Dental Association Foundation, and director of postdoctoral Clinical and Translational Science Award training. She is an active member of the American Association for Dental, Oral, and Craniofacial Research and the International Association for Dental Research. [3]

In March 2020 during the COVID-19 pandemic Webster-Cyriaque was involved with research at the Adams School of Dentistry at the UNC to see if mouthwash could be used to inactivate the Covid-19 virus. [6] Later that year she became the National Institute of Dental and Craniofacial Research's deputy director under the new Director Rena D’Souza. [3] [7] In 2022, Dr. Webster-Cyriaque received the International Association for Dental Research Distinguished Scientist Oral Pathology and Medicine Research Award.

Related Research Articles

<span class="mw-page-title-main">Mouthwash</span> Liquid rinse for oral hygiene

Mouthwash, mouth rinse, oral rinse, or mouth bath is a liquid which is held in the mouth passively or swilled around the mouth by contraction of the perioral muscles and/or movement of the head, and may be gargled, where the head is tilted back and the liquid bubbled at the back of the mouth.

<span class="mw-page-title-main">Oral candidiasis</span> Fungal infection

Oral candidiasis, also known as oral thrush among other names, is candidiasis that occurs in the mouth. That is, oral candidiasis is a mycosis of Candida species on the mucous membranes of the mouth.

<span class="mw-page-title-main">Leukoplakia</span> Medical condition

Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a white patch or plaque that develops in the oral cavity and is strongly associated with smoking. Leukoplakia is a firmly attached white patch on a mucous membrane which is associated with increased risk of cancer. The edges of the lesion are typically abrupt and the lesion changes with time. Advanced forms may develop red patches. There are generally no other symptoms. It usually occurs within the mouth, although sometimes mucosa in other parts of the gastrointestinal tract, urinary tract, or genitals may be affected.

Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised, especially those with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS). The white lesion, which cannot be scraped off, is benign and does not require any treatment, although its appearance may have diagnostic and prognostic implications for the underlying condition.

<span class="mw-page-title-main">National Institute of Dental and Craniofacial Research</span>

The National Institute of Dental and Craniofacial Research (NIDCR) is a branch of the U.S. National Institutes of Health. The institute aims to improve the oral, dental, and craniofacial health through research and the distribution of important health information to the American people.

An oral medicine or stomatology doctor/dentist has received additional specialized training and experience in the diagnosis and management of oral mucosal abnormalities including oral cancer, salivary gland disorders, temporomandibular disorders and facial pain, taste and smell disorders; and recognition of the oral manifestations of systemic and infectious diseases. It lies at the interface between medicine and dentistry. An oral medicine doctor is trained to diagnose and manage patients with disorders of the orofacial region, essentially as a "physician of the mouth".

Biodontics dentistry was founded by Dr. Edward Rossomando in 2001 as an area of oral health. Biodontics is funded by the United States National Institute of Dental and Craniofacial Research (NIDCR). The purpose of Biodontics is to expand the dental profession in its research capacity, skill sets, and entrepreneurship. An educational program known as the Biodontics Educational Program is held at the University of Connecticut School of Dental Medicine every July and assembles business leaders, entrepreneurs, management executives, scientists, architects, and dental manufacturers to give presentations and lectures to students from all dental schools.

<span class="mw-page-title-main">Creighton University School of Dentistry</span>

The Creighton University School of Dentistry is the dental school of Creighton University. It is located in the city of Omaha, Nebraska. It was one of the first dental schools in the United States, having been established in 1905.

The University of Washington School of Dentistry is the dental school of the University of Washington. It is located in Seattle, and is the only school of dentistry in the state of Washington. The school emphasizes research in anxiety, orofacial pain, tissue repair and regeneration, immune response to bacteria, and practice based research.

<span class="mw-page-title-main">UNC Adams School of Dentistry</span>

The UNC Claude A. Adams Jr. and Grace Phillips Adams School of Dentistry is the school of dentistry of the University of North Carolina. It is located in Chapel Hill, North Carolina, United States. It is currently ranked second among all dental schools in the U.S. and is consistently ranked among the best in the world according to two independent rankings. Founded in 1950 as the UNC School of Dentistry, it was the only dental school in North Carolina until 2011, when East Carolina University School of Dental Medicine became the second. In 2019, the school received its largest single donation of $27.68 million, resulting in a name change to honor Dr. Claude A. Adams Jr. and Grace Phillips Adams. Dr. Adams was a North Carolina dentist that practiced in Durham until his death in 2018.

<span class="mw-page-title-main">Salivary gland disease</span> Medical condition

Salivary gland diseases (SGDs) are multiple and varied in cause. There are three paired major salivary glands in humans: the parotid glands, the submandibular glands, and the sublingual glands. There are also about 800–1,000 minor salivary glands in the mucosa of the mouth. The parotid glands are in front of the ears, one on side, and secrete mostly serous saliva, via the parotid ducts, into the mouth, usually opening roughly opposite the second upper molars. The submandibular gland is medial to the angle of the mandible, and it drains its mixture of serous and mucous saliva via the submandibular duct into the mouth, usually opening in a punctum in the floor of mouth. The sublingual gland is below the tongue, on the floor of the mouth; it drains its mostly mucous saliva into the mouth via about 8–20 ducts, which open along the plica sublingualis, a fold of tissue under the tongue.

<span class="mw-page-title-main">Martha Somerman</span> American scientist

Martha J. Somerman is an internationally known researcher and educator in Medicine, focusing on defining the key regulators controlling development, maintenance, and regeneration of dental, oral, and craniofacial tissues. She is currently Chief Lab of Laboratory of Oral Connective Tissue Biology (LOCTB) at NIH's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and Director of the National Institute of Dental and Craniofacial Research (NIDCR), a part of the National Institutes of Health (NIH) located in Bethesda, Maryland, USA.

Human immunodeficiency virus salivary gland disease, is swelling of the salivary glands and/or xerostomia in individuals infected with human immunodeficiency virus.

Oral manifestations of systematic disease are signs and symptoms of disease occurring elsewhere in the body detected in the oral cavity and oral secretions. High blood sugar can be detected by sampling saliva. Saliva sampling may be a non-invasive way to detect changes in the gut microbiome and changes in systemic disease. Another example is tertiary syphilis, where changes to teeth can occur. Syphilis infection can be associated with longitudinal furrows of the tongue.

<span class="mw-page-title-main">Stephen J. Challacombe</span>

Stephen James Challacombe FRC(Path), FDSRCS, FMedSci, is professor of oral medicine at King's College in London, best known for research in oromucosal immunology and for developing the Challacombe scale for measuring the extent of dryness of the mouth. He led the team that laid out research challenges of global health inequalities and oral health, particularly relating to the oral manifestations of HIV.

John S. Greenspan, was an academic dentist/scientist and university administrator. His degrees and diplomas include BSc, BDS, PhD, FRCPath, FDSRCS (Eng). He was the Director-Emeritus of the AIDS Research Institute at the University of California, San Francisco (UCSF). He was also the founding Director of the UCSF AIDS Specimen Bank (1982-2017) and of the UCSF Oral AIDS Center (1986–2005).

<span class="mw-page-title-main">Niki Moutsopoulos</span> Greek periodontist and immunologist

Niki M. Moutsopoulos is a Greek periodontist and immunologist. She is a senior investigator in the oral immunity and infection section at the National Institute of Dental and Craniofacial Research. Moutsopoulos specializes in oral immunology and periodontitis. Her research program focuses on host-microbial interactions that can drive chronic inflammatory responses and tissue destruction in the oral cavity.

<span class="mw-page-title-main">Rena D'Souza</span> Clinician-scientist

Rena D'Souza is a clinician-scientist and the Director of the National Institute of Dental and Craniofacial Research. She was formerly the assistant vice president for academic affairs and education for health sciences at the University of Utah where she was also a Professor of Dentistry in the School of Dentistry and a Professor of Neurobiology and Anatomy in the School of Medicine.

<span class="mw-page-title-main">Isabel Garcia (dentist)</span>

A. Isabel Garcia is an American dentist and academic administrator serving as dean of the University of Florida College of Dentistry since 2015. She was deputy director of the National Institute of Dental and Craniofacial Research (NIDCR) from 2007 to 2014. Garcia was the acting NIDCR director from 2010 to 2011. She was a Rear Admiral Lower Half in the U.S. Public Health Service Commissioned Corps.

Cecile Arlene Feldman-Zohn is an American dental scientist who is a professor and Dean of the School of Dental Medicine at the Rutgers University. Her research considers dental informatics and health services research. She was elected Fellow of the American Association for the Advancement of Science in 2020.

References

  1. 1 2 "Jennifer Webster-Cyriaque, DDS, PhD". NIH. Retrieved February 6, 2022.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  2. Webster-Cyriaque, Jennifer (1998). The role of Epstein-Barr virus in hairy leukoplakia and other AIDS associated oral mucosal lesions (Ph.D. thesis). University of North Carolina at Chapel Hill. OCLC   47672170.
  3. 1 2 3 4 5 "NIDCR taps Webster-Cyriaque as deputy director". DrBicuspid.com. November 22, 2021. Retrieved February 17, 2022.
  4. "UNC Project-Malawi". globalhealth.unc.edu. Retrieved February 17, 2022.
  5. "UNC Project Partners | UNC Project-Malawi". globalhealth.unc.edu. Retrieved February 17, 2022.
  6. Jaramillo-Plata, Nayeli (March 23, 2021). "A tool to kill COVID-19 might be in your medicine cabinet: mouthwash". The Daily Tar Heel. Retrieved February 18, 2022.
  7. "Webster-Cyriaque Selected as Deputy Director, NIDCR". NIH. November 21, 2021. Retrieved February 6, 2022.PD-icon.svg This article incorporates text from this source, which is in the public domain .
PD-icon.svg This article incorporates public domain material from websites or documents of the National Institutes of Health.