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John Howard Sampson is an American neurosurgeon who was formerly chief of the department of neurosurgery at Duke University where he serves as a professor of surgery, biomedical engineering, immunology, and pathology. [1]
| This section of a biography of a living person does not include any references or sources .(November 2023) |
Sampson has written a variety of papers, including a paper in Nature on his clinical trial on the treatment of glioblastoma patients and another in how tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.
Newly diagnosed or recurrent primary or metastic brain tumors, including enrollment in clinical trials of new therapeutic agents (especially oncolytic poliovirus therapy, immunotherapy, vaccines and convection-enhanced delivery); posterior fossa tumors, such as acoustic neuromas or meningiomas; microsurgery for tic douloureux or trigeminal neuralgia, including microvascular decompression; microvascular decompression for hemifacial spasm, pituitary tumors, complex skull-base tumors; radiosurgery; evaluation and surgery for patients with the full spectrum of other neurosurgery pathologies.
Sampson has appeared on 60 Minutes and many other news networks for his work with glioblastoma cancer treatments.
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system.
Trigeminal neuralgia, also called Fothergill disease, tic douloureux, trifacial neuralgia, or suicide disease is a long-term pain disorder that affects the trigeminal nerve, the nerve responsible for sensation in the face and motor functions such as biting and chewing. It is a form of neuropathic pain. There are two main types: typical and atypical trigeminal neuralgia. The typical form results in episodes of severe, sudden, shock-like pain in one side of the face that lasts for seconds to a few minutes. Groups of these episodes can occur over a few hours. The atypical form results in a constant burning pain that is less severe. Episodes may be triggered by any touch to the face. Both forms may occur in the same person. It is regarded as one of the most painful disorders known to medicine, and often results in depression and suicide.
Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has very poor prognosis for survival. Initial signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke. Symptoms often worsen rapidly and may progress to unconsciousness.
Astrocytoma is a type of brain tumor. Astrocytomas originate from a specific kind of star-shaped glial cell in the cerebrum called an astrocyte. This type of tumor does not usually spread outside the brain and spinal cord and it does not usually affect other organs. After glioblastomas, astrocytomas are the second most common glioma and can occur in most parts of the brain and occasionally in the spinal cord.
Hemifacial spasm (HFS) is a rare neuromuscular disease characterized by irregular, involuntary muscle contractions (spasms) on one side (hemi-) of the face (-facial). The facial muscles are controlled by the facial nerve, which originates at the brainstem and exits the skull below the ear where it separates into five main branches.
The Duke University School of Medicine, commonly known as Duke Med, is the medical school of Duke University. It is located in the Collegiate Gothic-style West Campus of Duke University in Durham, North Carolina. The School of Medicine, along with the Duke University School of Nursing, Duke University Hospital, Duke Regional Hospital, Duke Children's Hospital, Duke Raleigh Hospital, and other affiliated hospitals, clinics, and laboratories, make up the Duke University Health System. Established in 1925 by James B. Duke, the School of Medicine has earned its reputation as an integral part of one of the world's foremost patient care and biomedical research institutions.
In 1916, the Daughters of Charity of Saint Vincent de Paul launched a Catholic hospital called St. Vincent's Medical Center Riverside. They provide full-service tertiary care at a capacity of 528 beds.
Decompressive craniectomy is a neurosurgical procedure in which part of the skull is removed to allow a swelling or herniating brain room to expand without being squeezed. It is performed on victims of traumatic brain injury, stroke, Chiari malformation, and other conditions associated with raised intracranial pressure. Use of this surgery is controversial.
Uppsala University Hospital in Uppsala, Sweden, is a teaching hospital for the Uppsala University Faculty of Medicine and the Nursing School. Uppsala University Hospital is owned and operated by the Uppsala County Council in cooperation with the university and serves, together with Enköping hospital in Enköping, as the primary hospitals for Uppsala County. It also fills the function of a tertiary referral hospital for the Uppsala/Örebro health care region and, for certain specialities, a tertiary referral hospital for the entire country of Sweden.
Joshua B. Bederson is an American neurosurgeon, Leonard I. Malis, MD/Corinne and Joseph Graber Professor of Neurosurgery, and System Chair of Neurosurgery at the Mount Sinai Health System in New York City. He is a Fellow of the American College of Surgeons, and an attending neurosurgeon at The Mount Sinai Hospital.
Dong-A University Hospital (동아대학교의료원) is a major general hospital affiliated with Dong-A University in Busan, South Korea.
Griffith Rutherford Harsh IV is an American neurosurgeon. In 2018, he became the chair of the department of neurological surgery at UC Davis Health.
The University of Miami Division of Surgical Neurooncology is the neurological surgery center at the University of Miami's Leonard M. Miller School of Medicine and one of the largest and most comprehensive programs for brain tumor treatment in the United States. It is located in Miami.
Barrow Neurological Institute is the world's largest neurological disease treatment and research institution, and is consistently ranked as one of the best neurosurgical training centers in the United States. Founded in 1962, the main campus is located at 350 W. Thomas Road, Phoenix, Arizona.
The Mischer Neuroscience Institute is a combined research and education effort between the Vivian L. Smith Department of Neurosurgery and the Department of Neurology at McGovern Medical School at UTHealth Houston and Memorial Hermann Hospital. Located in Houston, the Institute draws patients from around the world for specialized treatment of diseases of the brain and spine. It was the first center in Texas and one of only a few institutions in the country to fully integrate neurology, neurosurgery, neuroradiology, neuro-oncology, spine surgery, pain medicine and neurorehabilitation.
Dr. Matthias Gromeier is a Professor in the Department of Neurosurgery at Duke University Medical Center, who has developed a way to re-engineer a poliovirus to inspire the human immune system to kill cancer cells in a specific set of cancers. The re-engineered virus, called PVSRIPO, cannot replicate itself in normal cells, but can replicate itself in cancer cells that have an overabundance of the protein marker that the poliovirus targets.
Günther C. Feigl is an Austrian neurosurgeon. Feigl is an internationally renowned expert in minimally invasive neurosurgery. His main areas of expertise are skull base surgery and neurooncology. He specializes in the surgery of gliomas, minimally invasive endoscopy-assisted microvascular decompression in trigeminal neuralgia and facial hemispasm as well as the surgery of acoustic neuromas, tumors of the pineal gland and meningiomas of the skull base. Furthermore, his specialties comprise treatment of pituitary adenomas, spinal cord tumours and metastases as well as the area of pediatric neurosurgery.
Peter Edward Fecci is an American neurosurgeon, professor and researcher. He is an Associate Professor of Neurosurgery, Pathology and Immunology at Duke University School of Medicine. He also serves as Director of the Duke Center for Brain and Spine Metastasis, Director of the Brain Tumor Immunotherapy Program, Residency Program Director, and Associate Deputy Director of the Preston Robert Tisch Brain Tumor Center at Duke.
Duane A. Mitchell is an American physician-scientist and university professor. He is currently employed at the University of Florida College of Medicine, in Gainesville, Florida as the Assistant Vice President for Research, Associate Dean for Translational Science and Clinical Research, and Director of the University of Florida (UF) Clinical and Translational Science Institute. He is the Phyllis Kottler Friedman Professor in the Lillian S. Wells Department of Neurosurgery. and co-director of the Preston A. Wells Jr. Center for Brain Tumor Therapy. Mitchell is also the founder, President, and Chairman of iOncologi, Inc., a biotechnology company in Gainesville, FL specializing in immuno-oncology.
Linda M. Liau is an American neurosurgeon, neuroscientist, and the W. Eugene Stern Chair of the Department of Neurosurgery at the David Geffen School of Medicine at UCLA. Liau was elected to the Society of Neurological Surgeons in 2013 and the National Academy of Medicine in 2018. She has published over 230 research articles and a textbook, Brain Tumor Immunotherapy. She served as editor-in-chief of the Journal of Neuro-Oncology from 2007 to 2017.