Kristi S. Anseth | |
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Nationality | American |
Alma mater | University of North Dakota-Williston, Purdue University, University of Colorado |
Spouse | |
Scientific career | |
Fields | Chemical and Biological Engineering |
Institutions | University of Colorado |
Doctoral advisor | Chris Bowman |
Website | www |
External video | |
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“Bonfils Stanton Foundation 2015 Honoree: Kristi Anseth” | |
“NAS Research Briefings: Kristi S. Anseth - Biomaterials as Synthetic Extracellular Matrices“ |
Kristi S. Anseth (born 1969) is the Tisone Distinguished Professor of Chemical and Biological Engineering, an Associate Professor of Surgery, and a Howard Hughes Medical Investigator at the University of Colorado at Boulder. [1] [2] Her main research interests are the design of synthetic biomaterials using hydrogels, tissue engineering, and regenerative medicine.
Anseth was elected as a member into the National Academy of Engineering in 2009 for pioneering the rational design of biomaterials for tissue engineering, drug delivery, and biosensing applications.
Kristi Anseth grew up in Williston, North Dakota. She played on both the volleyball and basketball teams at the University of North Dakota-Williston, earning the honor of Academic All-American in her second year. [3]
Kristi Anseth transferred to Purdue University where she began her research career as an undergraduate student in the lab of Nicholas A. Peppas, receiving her Bachelor of Science in Chemical Engineering in 1992. [2] She obtained her PhD in 1994, working under Christopher N. Bowman, himself a former graduate student of Nicholas Peppas, at the University of Colorado. [3]
After post-doctoral work with Robert Langer at Massachusetts Institute of Technology and Thomas Cech, Anseth became an assistant professor at the Department of Chemical and Biological Engineering at the University of Colorado Boulder in 1996. [4] She currently leads the Anseth Research Group as the Tisone Distinguished Professor of Chemical and Biological Engineering. [5] She serves on Purdue's College of Engineering Advisory Council. [6]
Anseth is working at the intersection of materials science, chemistry and biology, [7] studying natural and synthetic hydrogels and using biomaterials to create an extracellular matrix to support three-dimensional cell enculturation. [8] [9]
Anseth is developing photopolymers that will change from soft to hard in response to cues such as ultraviolet light, and then degrade predictably over time. [10] Such materials could be used to for orthopedic repairs, functioning as a replacement for damaged areas of bone and then slowly being replaced by regrowth of natural material as the body heals. Her pioneering approach applies photopolymerization and photodegradation to enable precise control in space and time of hydrogels' structure and composition. This research involves fundamental investigations into the molecular dynamics of processes at the cell-biomaterial interface. [7]
Anseth is also working on the tissue engineering of biomaterials for the replacement of cartilage and heart valves. [8] By combining photopolymers and lab-grown cartilage her lab is creating living replacements for worn-out joints. The problem is more difficult than replacing bone because the cartilage in joints, unlike bone, does not have the ability to regrow. [10] [11]
She has published more than 250 papers and filed for at least 18 patents. [12] She has been involved in editorial activities of journals including Biomacromolecules , Journal of Biomedical Materials Research — Part A, Acta Biomaterialia , Progress in Materials Science , Biotechnology and Bioengineering [13] and Proceedings of the National Academy of Sciences of the United States of America. [14] In September 2014, she was elected the Vice President/President-Elect of the Materials Research Society (MRS), serving as Vice President in 2015 and President in 2016. [12]
In 1999, Anseth was named to the MIT Technology Review TR100 as one of the top 100 innovators in the world under the age of 35. [10]
Kristi Anseth was the first engineer, male or female, to be selected as a Howard Hughes Medical Investigator. [4] At age 40, she was the youngest member ever to be elected to both the National Academy of Engineering (2009) [15] and the Institute of Medicine (2009 [16] ). [2] In 2013, she was also elected to the National Academy of Sciences. [17] She shares the distinction of being a member of all three with chemical engineers Cato Laurencin, Robert S. Langer, Nicholas A. Peppas, Frances Arnold, and Rakesh K. Jain. As of 2015, she was also named to the National Academy of Inventors. [18] She was elected to the American Academy of Arts and Sciences in 2019. [19]
Other awards and honors include:
A hydrogel is a biphasic material, a mixture of porous, permeable solids and at least 10% by weight or volume of interstitial fluid composed completely or mainly by water. In hydrogels the porous permeable solid is a water insoluble three dimensional network of natural or synthetic polymers and a fluid, having absorbed a large amount of water or biological fluids. These properties underpin several applications, especially in the biomedical area. Many hydrogels are synthetic, but some are derived from nature. The term 'hydrogel' was coined in 1894.
Ali Khademhosseini is the director and CEO of the Terasaki Institute and former professor at the University of California-Los Angeles where he held a multi-departmental professorship in Bioengineering, Radiology, Chemical, and Biomolecular Engineering and the Director of Center for Minimally Invasive Therapeutics (C-MIT). From 2005 to 2017, he was a professor at Harvard Medical School, and the Wyss Institute for Biologically Inspired Engineering. His studies have been cited ~111,500 times. Khademhosseini is best known for developing hydrogels for tissue engineering and bioprinting.
Esmaiel Jabbari is a full professor of chemical engineering at the University of South Carolina.
Nicholas (Nikolaos) A. Peppas is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has provided seminal foundations based on the physics and mathematical theories of nanoscale, macromolecular processes and drug/protein transport and has led to numerous biomedical products or devices.
Linda Gay Griffith is an American biological engineer, and Professor of Biological Engineering and Mechanical Engineering at Massachusetts Institute of Technology, where she also directs the Center for Gynepathology Research.
Gordana Vunjak-NovakovicFRSC is a Serbian American biomedical engineer and university professor. She is a University Professor at Columbia University, as well as the Mikati Foundation Professor of Biomedical Engineering and Medical Sciences. She also heads the laboratory for Stem Cells and Tissue Engineering at Columbia University. She is part of the faculty at the Irving Comprehensive Cancer Center and the Center for Human Development, both found at Columbia University. She is also an honorary professor at the Faculty of Technology and Metallurgy at the University of Belgrade, an honorary professor at the University of Novi Sad, and an adjunct professor at the Department of Biomedical Engineering at Tufts University.
Edward Wilson Merrill was an American biomaterials scientist. He was one of the founders of bioengineering, and specifically the biomedical engineering field it developed from chemical engineering. Merrill was born to Edward Clifton Merrill (1881–1949), a chemical engineer and chief chemist of the United Drug Company (Rexall) and Gertrude Wilson (1895–1978).
Joanna Aizenberg is a professor of chemistry and chemical biology at Harvard University. She is the Amy Smith Berylson Professor of Materials Science at Harvard's School of Engineering and Applied Sciences, the co-director of the Kavli Institute for Bionano Science and Technology and a core faculty member of the Wyss Institute for Biologically Inspired Engineering. She is a prominent figure in the field of biologically inspired materials science, having authored 90 publications and holding 25 patents.
Molly S. Shoichet, is a Canadian science professor, specializing in chemistry, biomaterials and biomedical engineering. She was Ontario's first Chief Scientist. Shoichet is a biomedical engineer known for her work in tissue engineering, and is the only person to be a fellow of the three National Academies in Canada.
Christopher N. Bowman is an American chemical engineer, and the James and Catherine Patten Endowed Chair at University of Colorado Boulder.
Antonios Georgios Mikos is a Greek-American biomedical engineer who is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at Rice University. He specialises in biomaterials, drug delivery, and tissue engineering.
Jennifer Hartt Elisseeff is an American biomedical engineer, ophthalmologist and academic. She is the Morton Goldberg Professor and Director of the Translational Tissue Engineering Center at Johns Hopkins Department of Biomedical Engineering and the Wilmer Eye Institute with appointments in Chemical Engineering, Biomedical Engineering, Materials Science and Orthopedic Surgery. Elisseeff's research is in the fields of regenerative medicine and immunoengineering. She was elected a Fellow of the American Institute for Medical and Biological Engineering, the National Academy of Inventors, and a Young Global Leader by the World Economic Forum. In 2018, she was elected to the National Academy of Engineering for "development and commercial translation of injectable biomaterials for regenerative therapies." That same year, she was also elected to the National Academy of Medicine, and in 2019 she received the NIH Director's Pioneer Award. Her research has been cited over 23,000 times and she has an h-index over 75.
Julie Elizabeth Gough is a Professor of Biomaterials and Tissue Engineering at The University of Manchester. She specializes on controlling cellular responses at the cell-biomaterial interface by engineering defined surfaces for mechanically sensitive connective tissues.
Kristi Lynn Kiick is the Blue and Gold Distinguished Professor of Materials Science and Engineering at the University of Delaware. She studies polymers, biomaterials and hydrogels for drug delivery and regenerative medicine. She is a Fellow of the American Chemical Society, the American Institute for Medical and Biological Engineering, and of the National Academy of Inventors. She served for nearly eight years as the deputy dean of the college of engineering at the University of Delaware.
Milica Radisic is a Serbian Canadian tissue engineer, academic and researcher. She is a professor at the University of Toronto’s Institute of Biomaterials and Biomedical Engineering, and the Department of Chemical Engineering and Applied Chemistry. She co-founded TARA Biosystems and is a senior scientist at the Toronto General Hospital Research Institute.
Christine E. Schmidt is an American biomedical engineer. As a professor at the University of Florida, Schmidt was inducted into the Florida Inventors Hall of Fame for her creation of the Avance Nerve Graft which has "improved the lives of numerous patients suffering from peripheral nerve damage."
Elizabeth Cosgriff-Hernandez is an American biomedical engineer who is a professor at the University of Texas at Austin. Her work involves the development of polymeric biomaterials for medical devices and tissue regeneration. She also serves on the scientific advisory board of ECM Biosurgery and as a consultant to several companies on biostability evaluation of medical devices. Cosgriff-Hernandez is an associate editor of the Journal of Materials Chemistry B and Fellow of the International Union of Societies for Biomaterials Science and Engineering, Biomedical Engineering Society, Royal Society of Chemistry, and the American Institute for Medical and Biological Engineering.
Surita Bhatia is an American chemist who is professor and vice provost of faculty affairs at Stony Brook University. Her work considers the structure of soft materials, including polymeric hydrogels and colloidal glasses. She was elected Fellow of the American Institute of Chemical Engineers, the American Institute for Medical and Biological Engineering and the Society of Rheology in 2020.
Tatiana Segura is an American biomedical engineer who is a professor at Duke University. Her research considers biomedical engineering solutions to promote cell growth. She was elected Fellow of the American Institute for Medical and Biological Engineering in 2017 and awarded the Acta Biomaterialia Silver Medal in 2021.
Kristyn Simcha Masters is an American bioengineer who is professor and Chair of the Department of Bioengineering at the University of Colorado Denver. She works as Director of the Anschutz Medical Campus Center. Her research looks to create tissue-engineered models of disease, with a focus on cancer and cardiac disease.